piRNA processing by a trimeric Schlafen-domain nuclease.
Podvalnaya, Nadezda; Bronkhorst, Alfred W; Lichtenberger, Raffael; Hellmann, Svenja; Nischwitz, Emily; Falk, Torben; Karaulanov, Emil; Butter, Falk; Falk, Sebastian; Ketting, René F
A modified TurboID approach identifies tissue-specific centriolar components in C. elegans.
Holzer, Elisabeth; Rumpf-Kienzl, Cornelia; Falk, Sebastian; Dammermann, Alexander
Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry.
Baudrimont, Antoine; Paouneskou, Dimitra; Mohammad, Ariz; Lichtenberger, Raffael; Blundon, Joshua; Kim, Yumi; Hartl, Markus; Falk, Sebastian; Schedl, Tim; Jantsch, Verena
Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans
Perez-Borrajero, Cecilia; Podvalnaya, Nadezda; Holleis, Kay; Lichtenberger, Raffael; Karaulanov, Emil; Simon, Bernd; Basquin, Jérôme; Hennig, Janosch; Ketting, René F; Falk, Sebastian
A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA.
Cánovas-Márquez, José Tomás; Falk, Sebastian; Nicolás, Francisco E; Padmanabhan, Subramanian; Zapata-Pérez, Rubén; Sánchez-Ferrer, Álvaro; Navarro, Eusebio; Garre, Victoriano
In-depth interrogation of protein thermal unfolding data with MoltenProt.
Kotov, Vadim; Mlynek, Georg; Vesper, Oliver; Pletzer, Marina; Wald, Jiri; Teixeira-Duarte, Celso M; Celia, Herve; Garcia-Alai, Maria; Nussberger, Stephan; Buchanan, Susan K; Morais-Cabral, João H; Loew, Christian; Djinovic-Carugo, Kristina; Marlovits, Thomas C
Structural and antigenic investigation of Usutu virus envelope protein domain III.
Schoenenwald, Amelie; Pletzer, Marina; Skern, Tim
To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome.
Lingaraju, Mahesh; Schuller, Jan M; Falk, Sebastian; Gerlach, Piotr; Bonneau, Fabien; Basquin, Jérôme; Benda, Christian; Conti, Elena
Purification and Reconstitution of the S. cerevisiae TRAMP and Ski Complexes for Biochemical and Structural Studies.
Keidel, Achim; Conti, Elena; Falk, Sebastian
The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
Lingaraju, Mahesh; Johnsen, Dennis; Schlundt, Andreas; Langer, Lukas M.; Basquin, Jérôme; Sattler, Michael; Jensen, Torben Heick; Falk, Sebastian; Conti, Elena
Distinct and evolutionary conserved structural features of the human nuclear exosome complex.
Gerlach, Piotr; Schuller, Jan M; Bonneau, Fabien; Basquin, Jérôme; Reichelt, Peter; Falk, Sebastian; Conti, Elena
Structure of the nuclear exosome captured on a maturing preribosome.
Schuller, Jan Michael; Falk, Sebastian; Fromm, Lisa; Hurt, Ed; Conti, Elena
Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome.
Fromm, Lisa; Falk, Sebastian; Flemming, Dirk; Schuller, Jan Michael; Thoms, Matthias; Conti, Elena; Hurt, Ed
Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
Falk, Sebastian; Tants, Jan-Niklas; Basquin, Jerôme; Thoms, Matthias; Hurt, Ed; Sattler, Michael; Conti, Elena
Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.
Falk, Sebastian; Bonneau, Fabien; Ebert, Judith; Kögel, Alexander; Conti, Elena
Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Falk, Sebastian; Finogenova, Ksenia; Melko, Mireille; Benda, Christian; Lykke-Andersen, Søren; Jensen, Torben Heick; Conti, Elena
The conformational plasticity of eukaryotic RNA-dependent ATPases.
Ozgur, Sevim; Buchwald, Gretel; Falk, Sebastian; Chakrabarti, Sutapa; Prabu, Jesuraj Rajan; Conti, Elena
The RNA helicase FRH is an ATP-dependent regulator of CK1a in the circadian clock of Neurospora crassa.
Lauinger, Linda; Diernfellner, Axel; Falk, Sebastian; Brunner, Michael
The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.
Schuch, Benjamin; Feigenbutz, Monika; Makino, Debora L; Falk, Sebastian; Basquin, Claire; Mitchell, Phil; Conti, Elena
The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities.
Falk, Sebastian; Weir, John R; Hentschel, Jendrik; Reichelt, Peter; Bonneau, Fabien; Conti, Elena
The evolution and development of mollusc shells
Unraveling the Complexity of Crossover Regulation in C. elegans
Dynamics of 3D Genome Structure and Function
How superworms can help to solve our plastic waste crisis
Title to be announced
New players in an old pathway: biology of methanogens of the TACK superphylum
Targeting a gerozyme to reverse muscle aging and increase healthspan
Shaping morphogen gradients: from molecules to tissues and back
Title to be announced
Studying stressed cells by in situ structural biology
The role of non-canonical double strand break repair pathways in genome stability and diversity
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Arbuscular mycorrhiza development and function
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
The unanticipated roles of PICIs and phages in bacterial evolution
Chemical targeting of subcellular protein localization
Origin and diversification of gut-derived organs in chordates
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Connections between carbon and nitrogen cycling in the ocean
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
A mechanism for protein complex regulation at the mitochondrial surface
Striking physiology and cell biology of (marine) environmental microorganisms
Mechanisms controlling maintenance of cohesin dependent loops
Title to be announced