an enthusiastic scientist at the postdoctoral level who will join our team to investigate molecular mechanisms leading to age-linked cardiovascular disease in HGPS. In order to address this medically highly relevant question our lab has generated a new mouse model expressing the HGPS-linked lamin mutant in vascular endothelial cells. Our data show that an “aged” endothelium in HGPS causes perivascular fibrosis, diastolic cardiac dysfunction and premature death (J Clinic. Invest., 2019). Within the context of a European Network project involving partners from Stockholm, Munich, and Milan, you will investigate the role of non-coding RNAs, particularly miRNAs, in establishing pro-fibrotic signaling and test the possibility of miRNA-neutralizing reagents for new therapeutic approaches in pre-clinical settings.
a talented and motivated scientist with a PhD degree and documented research accomplishments in Molecular and Cell Biology (first author papers or preprints). The ideal candidate will have experience in studying vascular cells in vivo and in vitro, will be able to work independently and as part of a team, and will have strong organizational, written and verbal communication skills.
The great quality of science and great quality of life in Vienna ‐ Our lab is part of the Vienna BioCenter Campus, one of the main research hubs in Europe, providing also cutting edge technology services.
Send a curriculum vitae detailing current research interests, previous educational and research experience and contact details for two references to firstname.lastname@example.org. The position is available initially for up to two years starting October, 2021.