The candidate shall support ongoing research projects of the group but may also pursue an individual (sub)project. Therefore, a high level of independence and good organizational skills are required.
The work will involve diverse methods including cultivation of bacteria, genetic engineering, protein purification, techniques for detection of RNA and protein (e.g. Northern/Western blotting), methods addressing interaction of biomolecules (pull-down, two-hybrid system) and others. Experience in working with bacteria and prior knowledge in Microbiology are highly appreciated but not a prerequisite to fill the position. As we are located at an international institute, good English skills are required.
Infection diseases caused by viruses and bacteria represent major threats for human health, livestock and agriculture. Gram-negative bacteria of the family Enterobacteriaceae including pathogenic E. coli strains are of particular concern as resistances against currently used antibiotics are rapidly emerging, demanding for novel therapies. These bacteria are protected by a cell wall sandwiched between an inner and an outer membrane, which forms an effective barrier limiting the efficacy of several antibiotics.
The cell envelope is crucial in sensing the external environment, activating intracellular signaling pathways through which the bacteria adapt to changing conditions. When they are exposed to antibiotics or other stresses that target the envelope, they activate multiple stress response systems to protect themselves. In our projects, we want to understand how these regulatory networks respond to envelope perturbation and achieve protection and repair.
Our laboratory is located at the Max Perutz labs – a joint venture Institute for Molecular Biology of the University of Vienna and the Medical University of Vienna on the Vienna BioCenter Campus. The laboratory is fully equipped and the campus offers access to multiple research facilities. Additional information on the Görke lab.
A technician position in an excellent research institute that is highly dynamic and international. The work will be non-routine and allows to develop creativity and independent thinking. Working times can be organized in a flexible manner depending on the organisational skills and independence of the candidate.
The employment contract (40 h/week) will be according to the standard salary for CTA positions funded by the FWF (https://www.fwf.ac.at/en/research-funding/personnel-costs/). The position is first limited to 3 years.
Depending on the interests and achievements of the candidate, the position may develop into a PhD project provided that the criteria for joining the doctoral school are met (for more information, please see: https://www.viennabiocenter.org/education/).
Please send your application documents to firstname.lastname@example.org. Suitable candidates will be invited for interview. The position can be filled immediately. Applications will be considered until the position is filled.