Monday Seminar (Internal)
Speaker: MILETIC Sean (Marlovits), CABRERA QUIO Luis Enrique (Pauli), Moritz STALTNER (Ameres)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Understanding RNA-based regulatory processes in plants
Speaker: Xuemei Chen
Institute: University of California, Riverside
Host: Magnus Nordborg
Identification of novel regulators of H3K9 heterochromatin mediated gene silencing in mammals
Speaker: Karin Stecher
Institute: IMBA - Bell Group
How do proteins and small molecules function in the crowded cellular milieu
Speaker: Gideon Schreiber
Institute: Weizmann Institute of Science
Host: Kirstina Djinovic-Carugo
Solving protein structures and understanding genotype-phenotype maps using deep mutagenesis
Speaker: Ben Lehner
Institute: Center for Genomic Regulation, Barcelona
Host: Fred Berger
Quantitative profiling of chromatin dynamics reveals unique features of stem cells
Speaker: Simon Elsässer
Institute: Karolinska Institutet
Host: Frederic Berger
Cellular drivers of injury response and regeneration in the zebrafish heart
Speaker: Jan Philipp Junker
Institute: Max-Delbrück-Center for molecular medicine
Host: Andi Pauli
Monday Seminar (Internal)
Speaker: CHIA Kong Sam (Djamei), VAINORIUS Gintautas (Elling), PINTER Theresa (Busslinger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Understanding human brain development: from embryos to organoids
Speaker: Paola Arlotta
Institute: Harvard University
Host: Jürgen Knoblich
Phase transitions in early zebrafish development
Speaker: Carl-Philipp Heisenberg
Institute: IST Austria
Host: Elly Tanaka
Title to be announced
Speaker: Andrea Mair
Institute: Stanford University
Host: Yasin Dagdas, Markus Teige
Monday Seminar (Internal)
Speaker: ANDRIONE Mara (Zimmer), ALMEIDA Bernardo (Stark), SAVOVA Adriana (Martens)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Dynamic sumoylation and phosphorylation control meiotic chromosome segregation in C. elegans
Speaker: Federico Pelisch
Institute: School of Life Sciences, University of Dundee
Host: Verena Jantsch
Title to be announced
Speaker: Martin Polz
Institute: University of Vienna
Host: Magnus Nordborg
Maintenance of nucleolar homeostasis during development: The role of non-coding RNAs
Speaker: Eliezer Calo
Institute: MIT Department of Biology
Host: DK RNA Biology
Title to be announced
Speaker: Oliver Stork
Institute: Otto-von-Guericke University Magdeburg
Host: Wulf Haubensak
Controlling transposon mobility in a lake
Speaker: Eric Miska
Institute: Gurdon Institute, University of Cambridge
Host: DK RNA Biology
Monday Seminar (Internal)
Speaker: SGROMO Annamaria (Ameres), SCHNABL Jakob (Brennecke), HINTERNDORFER Matthias (Zuber)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Melina Schuh
Institute: MPI for Biophyical Chemistry
Host: Andi Pauli
Small RNA biology in the nematode C. elegans
Speaker: Rene Ketting
Institute: IMB Mainz
Host: DK RNA Biology
Non-conventional RNA processing mechanisms to cope with cellular stress
Speaker: Elif Karagöz
Institute: Max Perutz Labs
Host: DK RNA Biology
Monday Seminar (Internal)
Speaker: TURCO Eleonora (Martens), PHILLIPS Alexander William (Keays), NOGALES MORAL Adrian (Köhler)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
How to make of a photosynthetic animal? - a model systems' approach to coral-algal endosymbiosis
Speaker: Annika Guse
Institute: Centre for Organismal Studies Heidelberg (COS)
Host: Andi Pauli
Monday Seminar (Internal)
Speaker: STEPINAC Emma (Dong), REITER Franziska (Stark), HANDLER Dominik (Brennecke)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Ken Zaret
Institute: University of Pennsylvania
Host: Kikue Tachibana
Monday Seminar (Internal)
Speaker: KIM Jihoon (Koo), SIMS Jason (Schloegelhofer), KLAUS Loni (Stark)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Jose Jimenez-Gomez
Institute: INRA
Host: Daniele Filiault
Monday Seminar (Internal)
Speaker: PETRZILEK Jan (Ameres), SALAZAR THULA Oriana Ylida (Zimmer), BENTE Heinrich (Mittelsten Scheid)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Ton Schumacher
Institute: The Netherlands Cancer Institute
Host: Meinrad Busslinger
DK Chromosome Biology PhD Symposium: Chromopalooza - A festival to celebrate chromosome biology
Monday Seminar (Internal)
Speaker: BAUMGARTNER Lisa Christine (Brennecke), MERAI Zsuzsanna (Mittelsten Scheid), DAO Pauline (Tessmar)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Eileen Furlong
Institute: EMBL Heidelberg
Host: Alexander Stark
Title to be announced
Speaker: Harmit Malik
Institute: Fred Hutchinson Cancer Research Center
Host: Andi Pauli
Title to be announced
Speaker: Nicolas Plachta
Institute: Perelman School of Medicine, Philadelphia
Host: Alex Dammermann
Monday Seminar (Internal)
Speaker: KORDIC Darja (Clausen), HOFBAUER Pablo-Andres (Mendjan), DUKIC Dejan (Nordborg)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Dirk Goerlich
Institute: MPI Biophysical Chemistry
Host: Shamba Saha
Monday Seminar (Internal)
Speaker: BRADAMANTE Gabriele (Mittelsten Scheid), ELEWAUT Anais (Obenauf), PACHINGER Claudia (Dammermann)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: KNOCH Eva (Becker), EHRMANN Julian Friedrich (Clausen), HOFFMANN David (Penninger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: NAGASAKA Kota (Peters), LIU Grace Jie (Busslinger), SCHÄFER Markus (Zuber)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Genevieve Almouzni
Institute: Institute Curie
Host: Fred Berger
Monday Seminar (Internal)
Speaker: STEPHANI Madlen (Dagdas), ELLIS Thomas (Nordborg), HOI David Mario (Clausen)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Doug Higgs
Institute: MRC Weatherall Institute of Medicine
Host: Rushad Pavri
Title to be announced
Speaker: Petra Bulankova
Institute: VIB Gent
Host: Ortrun Mittelsten Scheid
Title to be announced
Speaker: Ian Henderson
Institute: University of Cambridge
Host: Magnus Nordborg
Title to be announced
Speaker: Karin De Visser
Institute: NKI
Host: Anna Obenauf
Monday Seminar (Internal)
Speaker: PFLUG Florian (Von Haesseler), GASSLER Johanna (Tachibana), MONTGOMERY Sean (Berger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Richard Henderson
Institute: MRC Laboratory of Molecular Biology
Host: Clemens Plaschka
Title to be announced
Speaker: Karen Oegema
Institute: UCSF
Host: Alex Dammermann
Title to be announced
Speaker: Silvia Ramunda
Institute: UCSF
Host: Yasin Dagdas
Monday Seminar (Internal)
Speaker: TRASSER Marieke (Mari-Ordinez), MITTER Michael (Gerlich), HAAS Lisa (Obenauf)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SERRA Nuria (Becker), DE ALMEIDA Melanie Talata (Zuber), PARYS Katarzyna (Belkhadir)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Paul Neve
Institute: Rothamsted Research, Harpenden
Host: Claude Becker
Monday Seminar (Internal)
Speaker: OSAKABE Akihisa (Berger), CRONIN Shona Mary (Obenauf), WU Szu-Hsien (Koo)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Andrea Schietinger
Institute: Memorial Sloan Kettering Cancer Center
Host: Elly Tanaka
Monday Seminar (Internal)
Speaker: HENDY Oliver James (Stark), PARINOV Anton (Zimmer), MORREALE Francesca (Clausen)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: BRIEDIS Krista Rene (Pauli), HISANAGA Tetsuya (Berger), GRÜNBACHER Sarah (Busslinger
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Julia Mahamid
Institute: Shambaditya Saha
Host: European Molecular Biology Laboratory
Monday Seminar (Internal)
Speaker: SHANMUGANATHAN Reshi (Becker), PETROVIC Mina (Gerlich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LEE Ji-Hyun (Koo), BELACIC Katarina (Haselbach), UMKEHRER Christian (Obenauf)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Alistair Boettiger
Institute: Stanford University
Host: Christa Bücker, Daniel Gerlich
Monday Seminar (Internal)
Speaker: LEESCH Katrin Friederike (Pauli), BYKOV Aleksandr (Cochella), LEE Ho-Seok (Belkhadir)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Valter Longo
Institute: USC Leonard David School of Gerontology
Host: Noelia Urban
Monday Seminar (Internal)
Speaker: NEUMAYR Christoph (Stark), CRESPO ENRIQUEZ Ivan (Urban), MARSONER Theodor (Campbell)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Eva Nogales
Institute: Lawrence Berkeley National Lab
Host: David Haselbach
Title to be announced
Speaker: Rahul Satija
Institute: New York Genome Center
Host: Andi Pauli
Title to be announced
Speaker: John Wherry
Institute: University of Pennsylvania
Host: Johannes Zuber
Monday Seminar (Internal)
Speaker: HOLSTEIN Felix (Obenauf), CUSHION Thomas David (Keays)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Gunnar Rätsch
Institute: ETH Zurich
Host: Alex Stark
Monday Seminar (Internal)
Speaker: JAEGLE Benjamin (Nordborg), RIESER Sarah Christine (Zuber), KOLESNIKOVA Sofia (Gerlich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: HAJDUSITS Bence (Clausen), HOHMANN Urlich (Brennecke/Plaschka), JAMGE Bhagyshree (Berger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: ROMANAUSKA Anete (Koehler), VOGT Vivien (Zuber), TREPTE Philipp (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SEREBRENI Leonid (Stark), GARBRECHT Joachim (Dammermann), VALLEBUENO Miguel (Swarts)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LEODOLTER Julia (Clausen), JELENIC Stela (Saha), SCHMUECKER Anne (Berger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: ZHAO Jierui (Dagdas), KOBAYASHI Wataru (Tachibana), TARDIVO Pietro (Tanaka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Jef Boeke
Institute: NYU Langone Health
Host: Luisa Cochella
Monday Seminar (Internal)
Speaker: ROSS James Julian (Brennecke), GUTIERREZ PEREZ Paula (Cochella), VALLOT Antoine (Tachibana)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Joanna Wysocka
Institute: Stanford University
Host: Christa Bücker, Kikue Tachibana
Monday Seminar (Internal)
Speaker: LUST Katharina (Tanaka), NAGUMO WONG Sakurako (Knoblich), CLAVEL Marion (Dagdas)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: MEREITER Stefan (Penninger), TIKANOVA Polina (Burga), CTORTECKA Claudia (Mendjan)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Eran Segal
Institute: Weizmann Institute
Host: Ortrun Mittelsten Scheid
Monday Seminar (Internal)
Speaker: BOSONE Camilla (Knoblich), BLAHA Andreas (Pauli)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Richard Youle
Institute: NIH
Host: Sascha Martens
Title to be announced
Speaker: Stefanie Sprunck
Institute: Regensburg University
Host: Andi Pauli/Ortrun Mittelsten Scheid
Monday Seminar (Internal)
Speaker: BENNABI Isma (Gerlich), DIMITROVA Mariya (Peters), MASSELINK Wouter (Tanaka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: FALCON CHAVEZ Francisco Javier (Tanaka), CALDERON DOMINGUEZ Lesly (Busslinger), ANDREEV Veselin Ivanov (Brennecke)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: ASANOVIC Igor (Martinez), TAVERNINI Katherina (Urban), GUTIERREZ PEREZ Irene (Peters)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Andrew Dillin
Institute: University of California, Berkeley
Host: Yasin Dagdas
Title to be announced
Speaker: Fay-Wie Li
Institute: Cornell University
Host: Fred Berger
Monday Seminar (Internal)
Speaker: REY Ulises (Zimmer), UIJTTEWAAL Esther (Elling), SCHNEIDER Maximilian (Gerlich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Jennifer Lippincott-Schwartz
Institute: Janelia Farm
Host: Kristina Djinovic Carugo
Monday Seminar (Internal)
Speaker: STOCK Jessica (Pauli), PICCHIANTI Lorenzo (Dagdas), SIDHAYE Jaydeep (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: GABARRO SOLANAS Rut (Urban), KAGAWA Harunobu (Rivron), BECERRIL PEREZ Fernando (Tanaka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: HOFBAUER Lorena (Stark), DEYETT Alison Ann (Mendjan), VUNJAK Milica (Versteeg)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Steve Jackson
Institute: Gurdon Research Institute
Host: Rushad Pavri
Monday Seminar (Internal)
Speaker: SCHENK Robyn (Busslinger), LEE Joonsun (Elling), RODRIGUES VIANA Angela Maria (Ameres)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Valentina Greco
Institute: Yale University School of Medicine
Host: Noelia Urban
Monday Seminar (Internal)
Speaker: MILJKOVIC Frane (Köhler), STOCKINGER Alexander (Raible), SUGIURA Takuji (Tanaka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Naama Barkai
Institute: Weizmann Institute of Science
Host: Luisa Cochella
Monday Seminar (Internal)
Speaker: DA CUNHA E SILVA MARTINS COSTA Catarina (Knoblich), VAN DER LELIJ Petra (Peters), FAHRENBERGER Martin (Von Haeseler)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: John Marioni
Institute: EMBL-EBI
Host: Arndt von Haeseler
Monday Seminar (Internal)
Speaker: DUXBURY Zane (Becker), VOLKOVA Ksenia (Köhler), RAUSCHMEIER Rene (Busslinger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Christopher Vakoc
Institute: Cold Spring Harbor Laboratory
Host: Johannes Zuber
Monday Seminar (Internal)
Speaker: ANISIMOVA Aleksandra (Karagöz), LIN Tzi-Yang (Tanaka),
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: KHANDEKAR Ameya (Martinez), LOUBIERE Vincent (Stark), NGUYEN Vu (Mittelsten Scheid)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LANDLER Lukas (Keays), CLARKE Amy (Zagrovic)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Clifford Brangwynne
Institute: Princeton University
Host: Daniel Gelrich
Monday Seminar (Internal)
Speaker: HAENDELER Simon (Von Haeseler), KRAMMER Teresa (Tanaka), DENEKE Victoria (Pauli)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LEITNER Marie-Christin (Mendjan), YU Changwei (Brennecke), MANDLBAUER Ariane (Cochella)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LORENZO ORTS Laura (Pauli), HORN Sabrina (Peters), SEONG Jinwoo (Rivron)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SAAD RODRIGUES Carolina (Schloegelhofer), OTSUKI Leo (Tanaka), SCHMIDT Clara (Mendjan)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LÖFKE Christian (Dagdas), SANTILLAN Emilio Manuel (Cochella), TAKACS Zsuzsanna (Gerlich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: BATTY Paul Daniel (Gerlich), JACOBS Jelle (Stark)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: David Sabatini
Institute: MIT, Whitehead Institute
Host: Yasin Dagdas
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What determines the complexity of higher organisms? No correlation has been found to DNA content and gene number and therefore studies in the field are now focusing on post-transcriptional processes and the impact of the dynamic transcriptome on gene expression. We are focussing on the questions , how alternative splicing influences protein diversity and mRNA isoform transcript levels in the model plant Arabidopsis thaliana and how these specifics are regulated by developmental and environmental cues.
In plants, the significance of alternative splicing was long underestimated, but we and others have shown that it greatly impacts on development and response to the environment. We therefore are using high through-put RNAseq techniques to define the rules and targets of alternative splicing. In addition, we are investigating SR (Ser/Arg) proteins, an important family of splicing factors, and several regulatory proteins like SRPK kinases, helicases and cyclophilins that are essential to drive and regulate the splicing process. To elucidate their mechanisms of action some of the plant SR proteins and cyclophilins are currently characterized in greater detail in terms of their RNA targets, interacting proteins and their impact on alternative splicing and gene expression, in particular during flowering and UV-stress response. Importantly, light signalling pathways and the regulation of alternative splicing events by light are under investigation as they are key in plant development.
Exitrons are exon-like introns located within protein-coding exons. Removal or retention of exitrons through alternative splicing increases proteome complexity and thus adds to phenotypic diversity. Exitron abundance and characteristics are conserved between Arabidopsis and humans. Exitron splicing occurs in many important human protein-coding genes including those involved in cancer.
Alternative splicing may cause retention of complete introns (IR). IR often results in transcripts with signatures for Non-sense Mediated Decay (NMD), however our analyses have shown that they are not degraded by NMD. By using molecular beacons with confocal laser scanning microscopy we show that these IR transcripts stay in the nucleus therefore avoiding NMD in the cytoplasm.
In plants light influences many adaptation processes. Our work shows that light/dark conditions affect alternative splicing of several genes. This requires functional chloroplasts and is also observed in roots when signaling through the photosynthetic tissue is not interrupted. We show that the reduced pool of plastoquinones initiates retrograde signaling regulating nuclear alternative splicing.
In rare cases cyclophilins (peptidyl-prolyl cis/trans isomerases; PPIase) possess an RNA binding domain. Previously, we have identified Cyp59 as a regulator of transcription, changing phosphorylation of Pol II. Here we identify the RNA binding motif of Cyp59 which is highly conserved and present in 70 % of mRNAs. Binding of the RNA motif inhibits PPIase activity in vitro, suggesting an important function in transcription regulation.
A chloroplast retrograde signal regulates nuclear alternative splicing.
Petrillo, Ezequiel; Herz, Micaela A Godoy; Fuchs, Armin; Reifer, Dominik; Fuller, John; Yanovsky, Marcelo J; Simpson, Craig; Brown, John W S; Barta, Andrea; Kalyna, Maria; Kornblihtt, Alberto R
Localization and dynamics of plant splicing regulators
A.S.N. Reddy,Irene S. Day, Janett Göhring and Andrea Barta
Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis.
Kalyna, Maria; Simpson, Craig G; Syed, Naeem H; Lewandowska, Dominika; Marquez, Yamile; Kusenda, Branislav; Marshall, Jacqueline; Fuller, John; Cardle, Linda; McNicol, Jim; Dihn, Huy Q; Barta, Andrea; Brown, John W S
Andrea Barta is scientific supervisor of the FWF funded Doctoral Program "RNA Biology".
The Group Barta participates in the Special Research Program (SFB) "RNA-Reg - RNA regulation of the transcriptome" funded by the Austrian Science Fund FWF. SFB's are peer-reviewed, highly interactive research networks, established to foster long-term, interdisciplinary co-operation of local research groups working on the frontiers of their thematic areas.
Member and Vice-Chair of the Senate of the Christian Doppler Society a funding agency for translational research.