Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma.
Breitenecker, Kristina; Hedrich, Viola; Pupp, Franziska; Chen, Doris; ?ezní?ková, Eva; Ortmayr, Gregor; Huber, Heidemarie; Weber, Gerhard; Balcar, Lorenz; Pinter, Matthias; Mikulits, Wolfgang
SORORIN is an evolutionary conserved antagonist of WAPL
Ignacio Prusén Mota, Marta Galova, Alexander Schleiffer, Tan-Trung Nguyen, Ines Kovacikova, Tomoko Nishiyama, Juraj Gregan, Jan-Michael Peters, View ORCID ProfilePeter Schlögelhofer
Spo11 generates gaps through concerted cuts at sites of topological stress.
Prieler, Silvia; Chen, Doris; Huang, Lingzhi; Mayrhofer, Elisa; Zsótér, Soma; Vesely, Magdalena; Mbogning, Jean; Klein, Franz
Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation.
Sanchez, Aurore; Adam, Céline; Rauh, Felix; Duroc, Yann; Ranjha, Lepakshi; Lombard, Bérangère; Mu, Xiaojing; Wintrebert, Mélody; Loew, Damarys; Guarné, Alba; Gnan, Stefano; Chen, Chun-Long; Keeney, Scott; Cejka, Petr; Guérois, Raphaël; Klein, Franz; Charbonnier, Jean-Baptiste; Borde, Valérie
RNA polymerase II-binding aptamers in human ACRO1 satellites disrupt transcription in cis
Boots, Jennifer L; von Pelchrzim, Frederike; Weiss, Adam; Zimmermann, Bob; Friesacher, Theres; Radtke, Maximilian; Zywicki, Marek; Chen, Doris; Matylla-Kuli?ska, Katarzyna; Zagrovic, Bojan; Schroeder, Renée
Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation.
Challa, Kiran; Fajish V, Ghanim; Shinohara, Miki; Klein, Franz; Gasser, Susan M; Shinohara, Akira
Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation.
Karányi, Zsolt; Halász, László; Acquaviva, Laurent; Jónás, Dávid; Hetey, Szabolcs; Boros-Oláh, Beáta; Peng, Feng; Chen, Doris; Klein, Franz; Géli, Vincent; Székvölgyi, Lóránt
Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation.
Polakova, Silvia; Molnarova, Lucia; Hyppa, Randy W; Benko, Zsigmond; Misova, Ivana; Schleiffer, Alexander; Smith, Gerald R; Gregan, Juraj
Molecular characterization of HIV-1 genome in fission yeast Schizosaccharomyces pombe.
Nkeze, Joseph; Li, Lin; Benko, Zsigmond; Li, Ge; Zhao, Richard Y
Transcription dynamically patterns the meiotic chromosome-axis interface.
Sun, Xiaoji; Huang, Lingzhi; Markowitz, Tovah E; Blitzblau, Hannah G; Chen, Doris; Klein, Franz; Hochwagen, Andreas
Mal3, the Schizosaccharomyces pombe homolog of EB1, is required for karyogamy and for promoting oscillatory nuclear movement during meiosis.
Polakova, Silvia; Benko, Zsigmond; Zhang, Lijuan; Gregan, Juraj
Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis.
Martin Xaver, Lingzhi Huang, Doris Chen and Franz Klein
Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery.
Carballo, Jesús A; Panizza, Silvia; Serrentino, Maria Elisabetta; Johnson, Anthony L; Geymonat, Marco; Borde, Valérie; Klein, Franz; Cha, Rita S
Ubc9 sumoylation controls SUMO chain formation and meiotic synapsis in Saccharomyces cerevisiae.
Klug, Helene; Xaver, Martin; Chaugule, Viduth K; Koidl, Stefanie; Mittler, Gerhard; Klein, Franz; Pichler, Andrea
Spo11-accessory proteins link double-strand break sites to the chromosome axis in early meiotic recombination.
Panizza, Silvia; Mendoza, Marco A; Berlinger, Marc; Huang, Lingzhi; Nicolas, Alain; Shirahige, Katsuhiko; Klein, Franz
Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.
Baudrimont, Antoine; Penkner, Alexandra; Woglar, Alexander; Machacek, Thomas; Wegrostek, Christina; Gloggnitzer, Jiradet; Fridkin, Alexandra; Klein, Franz; Gruenbaum, Yosef; Pasierbek, Pawel; Jantsch, Verena
Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity.
Mendoza-Ferri, Maria G; Hartinger, Christian G; Mendoza, Marco A; Groessl, Michael; Egger, Alexander E; Eichinger, Rene E; Mangrum, John B; Farrell, Nicholas P; Maruszak, Magdalena; Bednarski, Patrick J; Klein, Franz; Jakupec, Michael A; Nazarov, Alexey A; Severin, Kay; Keppler, Bernhard K
Separation of roles of Zip1 in meiosis revealed in heterozygous mutants of Saccharomyces cerevisiae.
Klutstein, Michael; Xaver, Martin; Shemesh, Ronen; Zenvirth, Drora; Klein, Franz; Simchen, Giora
Novel roles for selected genes in meiotic DNA processing.
Jordan, Philip W; Klein, Franz; Leach, David R F
A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene.
Uanschou, Clemens; Siwiec, Tanja; Pedrosa-Harand, Andrea; Kerzendorfer, Claudia; Sanchez-Moran, Eugenio; Novatchkova, Maria; Akimcheva, Svetlana; Woglar, Alexander; Klein, Franz; Schlögelhofer, Peter
Voyage of the Starships: giant transposons as crucibles of evolution
Parthenogenesis, cryptobiosis, and the survival in extreme environmental conditions
Evading ageing: Mitochondrial and proteostatic adaptations in oocytes
Genomes in Rhodnius prolixus symbiotic system
Stem cells, immune evasion and metastasis in colorectal cancer
Ubiquitin & Friends Symposium 2024
The Ubiquitin & Friends Symposium is an annual international meeting taking place in the beautiful capital of Austria, aiming to bring together scholars from various fields studying ubiquitin/Ubl biology and protein degradation in a personal, family-like atmosphere, as suggested by the name.
The evolution and development of mollusc shells
Unraveling the Complexity of Crossover Regulation in C. elegans
Dynamics of 3D Genome Structure and Function
How superworms can help to solve our plastic waste crisis
Title to be announced
New players in an old pathway: biology of methanogens of the TACK superphylum
Shaping morphogen gradients: from molecules to tissues and back
Title to be announced
Studying stressed cells by in situ structural biology
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Arbuscular mycorrhiza development and function
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
The unanticipated roles of PICIs and phages in bacterial evolution
Chemical targeting of subcellular protein localization
Origin and diversification of gut-derived organs in chordates
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Connections between carbon and nitrogen cycling in the ocean
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
Striking physiology and cell biology of (marine) environmental microorganisms
Mechanisms controlling maintenance of cohesin dependent loops
Title to be announced