A Ca2+-Mediated Switch of Epiplakin from a Diffuse to Keratin-Bound State Affects Keratin Dynamics
Ratajczyk, Sonia; Drexler, Corinne; Windoffer, Reinhard; Leube, Rudolf E; Fuchs, Peter
Retinal regions shape human and murine Müller cell proteome profile and functionality.
Kaplan, Lew; Drexler, Corinne; Pfaller, Anna M; Brenna, Santra; Wunderlich, Kirsten A; Dimitracopoulos, Andrea; Merl-Pham, Juliane; Perez, Maria-Theresa; Schlötzer-Schrehardt, Ursula; Enzmann, Volker; Samardzija, Marijana; Puig, Berta; Fuchs, Peter; Franze, Kristian; Hauck, Stefanie M; Grosche, Antje
Comparative genomics reveals evolutionary loss of epiplakin in cetaceans.
Fuchs, Peter; Drexler, Corinne; Ratajczyk, Sonia; Eckhart, Leopold
Functional and Genetic Analysis of Epiplakin in Epithelial Cells
Sandra Szabo, Karl L. Wögenstein, Peter Fuchs
Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.
Szabo, Sandra; Wögenstein, Karl L; Österreicher, Christoph H; Guldiken, Nurdan; Chen, Yu; Doler, Carina; Wiche, Gerhard; Boor, Peter; Haybaeck, Johannes; Strnad, Pavel; Fuchs, Peter
Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.
Wögenstein, Karl L; Szabo, Sandra; Lunova, Mariia; Wiche, Gerhard; Haybaeck, Johannes; Strnad, Pavel; Boor, Peter; Wagner, Martin; Fuchs, Peter
Intermediate filament linker proteins: Plectin and BPAG1.
Fuchs, P. and Wiche, G.
Targeted Proteolysis of Plectin Isoform 1a Accounts for Hemidesmosome Dysfunction in Mice Mimicking the Dominant Skin Blistering Disease EBS-Ogna.
Walko, Gernot; Vukasinovic, Nevena; Gross, Karin; Fischer, Irmgard; Sibitz, Sabrina; Fuchs, Peter; Reipert, Siegfried; Jungwirth, Ute; Berger, Walter; Salzer, Ulrich; Carugo, Oliviero; Castañón, Maria J; Wiche, Gerhard
Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity.
Fuchs, Peter; Zörer, Michael; Reipert, Siegfried; Rezniczek, Günther A; Propst, Friedrich; Walko, Gernot; Fischer, Irmgard; Bauer, Jan; Leschnik, Michael W; Lüscher, Bernhard; Thalhammer, Johann G; Lassmann, Hans; Wiche, Gerhard
Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption.
Spazierer, Daniel; Raberger, Julia; Gross, Karin; Fuchs, Peter; Wiche, Gerhard
Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms.
Konieczny, Patryk; Fuchs, Peter; Reipert, Siegfried; Kunz, Wolfram S; Zeöld, Anikó; Fischer, Irmgard; Paulin, Denise; Schröder, Rolf; Wiche, Gerhard
Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
Naetar, Nana; Korbei, Barbara; Kozlov, Serguei; Kerenyi, Marc A; Dorner, Daniela; Kral, Rosana; Gotic, Ivana; Fuchs, Peter; Cohen, Tatiana V; Bittner, Reginald; Stewart, Colin L; Foisner, Roland
Conditional targeting of plectin in prenatal and adult mouse stratified epithelia causes keratinocyte fragility and lesional epidermal barrier defects.
Ackerl, Reinhard; Walko, Gernot; Fuchs, Peter; Fischer, Irmgard; Schmuth, Matthias; Wiche, Gerhard
Plectin scaffolds recruit energy-controlling AMP-activated protein kinase (AMPK) in differentiated myofibres.
Gregor, Martin; Zeöld, Aniko; Oehler, Susanne; Marobela, Kerstin Andrä; Fuchs, Peter; Weigel, Günter; Hardie, D Graham; Wiche, Gerhard
Epiplakin is dispensable for skin barrier function and for integrity of keratin network cytoarchitecture in simple and stratified epithelia.
Spazierer, Daniel; Fuchs, Peter; Reipert, Siegfried; Fischer, Irmgard; Schmuth, Matthias; Lassmann, Hans; Wiche, Gerhard
Voyage of the Starships: giant transposons as crucibles of evolution
Parthenogenesis, cryptobiosis, and the survival in extreme environmental conditions
Evading ageing: Mitochondrial and proteostatic adaptations in oocytes
Genomes in Rhodnius prolixus symbiotic system
Stem cells, immune evasion and metastasis in colorectal cancer
Ubiquitin & Friends Symposium 2024
The Ubiquitin & Friends Symposium is an annual international meeting taking place in the beautiful capital of Austria, aiming to bring together scholars from various fields studying ubiquitin/Ubl biology and protein degradation in a personal, family-like atmosphere, as suggested by the name.
The evolution and development of mollusc shells
Unraveling the Complexity of Crossover Regulation in C. elegans
Dynamics of 3D Genome Structure and Function
How superworms can help to solve our plastic waste crisis
Title to be announced
New players in an old pathway: biology of methanogens of the TACK superphylum
Shaping morphogen gradients: from molecules to tissues and back
Title to be announced
Studying stressed cells by in situ structural biology
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Arbuscular mycorrhiza development and function
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
The unanticipated roles of PICIs and phages in bacterial evolution
Chemical targeting of subcellular protein localization
Origin and diversification of gut-derived organs in chordates
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Connections between carbon and nitrogen cycling in the ocean
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
Striking physiology and cell biology of (marine) environmental microorganisms
Mechanisms controlling maintenance of cohesin dependent loops
Title to be announced