Understanding biological processes requires a combination of cell biology and biochemistry to see molecular functions in a cellular context. After an era dominated by sequencing, uncovering protein functions will now be critical in order to understand biology also at a systems level. I am aiming at providing practical knowledge to address molecular functions in a cellular context, e.g. in the regulation metabolism or in organelles. I am teaching general Biochemistry (3h) as well as Plant Biochemistry and Metabolism and Cellular Organization in Molecular Plant Biology and Molecular Plant Physiology, an advanced Biochemistry seminar, and literature- and project planning seminars as well as the basic biochemistry laboratory course.
My lab investigates molecular mechanisms of cellular acclimation to environmental changes in plants and algae, particularly protein kinase- and calcium-mediated signalling pathways to stress. We study calcium-signalling and regulation of metabolism and the role of calcium-dependent protein kinases (CDPKs) in stress acclimation at various levels ranging from regulation of membrane proteins (Mehlmer et al., 2010; Latz et al., 2013), soluble enzymes (Lambeck et al., 2010; Rietz et al., 2010) to metabolic adjustment by regulation of transcription (Mair et al., 2015; Pedrotti et al., 2018). More recently also organellar signalling came into focus of our work (Stael et al., 2012; Wurzinger et al., 2018).
Studies of Chemistry at the University of Hannover (DE), 1995 PhD in Biochemistry on regulation of Calvin-cycle enzymes (IPK Gatersleben, DE), 1995-1996 Humboldt fellow at UT Southwestern (Dallas, TX, USA), 1998-2000 Marie Curie fellow at the University of Vienna, 2000-2004 Senior postdoc on MAP kinase signalling and stress responses in plants, 2002 Habilitation in Biochemistry, since 2004 self-funded group leader at the University of Vienna with projects on Ca2+ dependent protein kinases and organellar signalling.
orcid.org/0000-0001-7204-1379 ResearcherID: R-6443-2016
Systematic identification and functional characterization of transcriptional regulators
The mineralosphere as microhabitat for microbe, mineral and organic matter interaction in soils
Activation and regulation of plant immunity by secreted signaling peptides
Transcription start site selection is environmentally controlled to diversify the proteome in eukaryotes
How evolutionary interplay between sexes can help us define phenotypes and develop drugs
Mining for protein-protein interactions with AlphaFold: Lessons from Genome Maintenance
Title to be announced
The magical Martian Methane mystery and other stories about life on Mars
Probing life at the nanoscale - one molecule at a time
The Underworld of Deep-Sea Hydrothermal Vents
Epigenetic regulation of germline development
Sister chromatid cohesion is mediated by individual cohesin complexes
Origin and evolution of a defensive symbiosis in tortoise leaf beetles
Capturing conformational transitions in the ubiquitin conjugation cascade
18th Microsymposium on RNA Biology
The „Microsymposium on RNA Biology“ is an international conference that brings together young scientists, junior and senior group leaders, and company representatives from all over the world to present and discuss their latest findings in the exciting field of small RNAs and beyond. The Microsymposium was founded in 2005 and has established itself as the major small RNA meeting in Europe. It is organized by the four research institutions IMBA, IMP, GMI and the Max Perutz Labs as well as by the RNA community of the Vienna BioCenter.
Transformation Reactions of Organic Contaminants and Oxygen: From Field Sites to Reaction Mechanisms
Title to be announced
Multiscale plant bioimaging using advanced microscopy
Evading ageing: Mitochondrial and proteostatic adaptations in oocytes
Parthenogenesis, cryptobiosis, and the survival in extreme environmental conditions
Ubiquitin & Friends Symposium 2024
The Ubiquitin & Friends Symposium is an annual international meeting taking place in the beautiful capital of Austria, aiming to bring together scholars from various fields studying ubiquitin/Ubl biology and protein degradation in a personal, family-like atmosphere, as suggested by the name.
Genomes in Rhodnius prolixus symbiotic system
Stem cells, immune evasion and metastasis in colorectal cancer
The evolution and development of mollusc shells
Unraveling the Complexity of Crossover Regulation in C. elegans
Dynamics of 3D Genome Structure and Function
How superworms can help to solve our plastic waste crisis
New players in an old pathway: biology of methanogens of the TACK superphylum
Shaping morphogen gradients: from molecules to tissues and back
Studying stressed cells by in situ structural biology
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
The unanticipated roles of PICIs and phages in bacterial evolution
Origin and diversification of gut-derived organs in chordates
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Connections between carbon and nitrogen cycling in the ocean
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
Striking physiology and cell biology of (marine) environmental microorganisms
Mechanisms controlling maintenance of cohesin dependent loops
Title to be announced