The instructions that make us who we are translate into a diverse array of complex and highly regulated processes that occur precisely and on time in every single cell. Mistakes in these processes can lead to disease. Scientists at the Max Perutz Labs study fundamental cellular and developmental processes at a mechanistic level.
Genetic information is encoded in genes, embedded in chromatin, and organized in chromosomes. Its implementation is dynamically regulated at different levels from DNA to RNA. At the Max Perutz Labs, scientists focus on fundamental processes of inheritance, nuclear architecture, genome organization, and RNA biology from bacteria to humans.
Biological processes are driven by the coordinated interaction of molecules within cells and tissues. The Max Perutz Labs studies how structure is related to function, the dynamics and energetics of the macromolecules that are at the heart of these processes, and the networks in which they operate. We aim to elucidate the mechanisms that shape our normal physiology and rationalize the role of aberrant macromolecules in disease.
Hans Tuppy (1924-2024)
After completing his studies in chemistry at the University of Vienna, Hans Tuppy ventured to Cambridge on the recommendation of future Nobel laureate Max Perutz. There, he contributed to pioneering research on the structure of insulin.
Throughout his distinguished career, Hans Tuppy's scientific work spanned a broad range of field - including hormones, nucleic acids, and viruses. His contributions to blood group chemistry, peptide science, and protein biochemistry are reflected in a wealth of influential publications.
Beyond his achievements in the laboratory, Hans Tuppy played a key role in shaping Austrian academia and scientific policy, leaving a lasting legacy on both fronts. Even in his later years, he remained active and deeply committed to science. From his office at the Max Perutz Labs, he continued his work with unwavering dedication - often arriving earlier and leaving later than many of his younger colleagues. He is fondly remembered as a brilliant scientist, a generous mentor, and a valued companion whose presence was a constant source of inspiration.
