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Unnatural selection
Aug 04, 2025
Hospital-acquired fungal infections, which pose a serious risk to immunocompromised patients, are a growing global health challenge. In a new study published in Cell Reports, first author Trinh Phan-Canh, a PhD student at Perutz, discovered that a morphogenetic switch between White and Brown phenotypes in the human pathogen Candida auris correlates with virulence, pathogenicity, and drug resistance, with implications for the treatment of systemic Candida infections.