This year, the Microsymposium is a two-day international conference that brings together young scientists, junior and senior group leaders from all over the world to present and discuss their latest findings in the exciting field of small RNAs and other RNA biology related topics. The Microsymposium was founded in 2005 and has established itself as the major small RNA meeting in Europe. It is organized by the four research institutions GMI, IMBA, IMP, and Max Perutz Labs, as well as by the RNA community of the Vienna BioCenter.
The Microsymposium is a registration-free meeting for all its participants!
Centrioles are surrounded by a dense meshwork of proteins called the pericentriolar material (PCM), which together form centrosomes, the main microtubule-organizing centers of the cell. Alexander Dammermann’s group has discovered that centrosomes persist without centrioles in post-mitotic neurons of C. elegans. Key components of the PCM are expressed and incorporated into these centrosomes independent of centrioles and known mitotic regulators. The study, published in Current Biology, suggests that the assembly and maintenance of mitotic and non-mitotic centrosomes may be different.
The Austrian Science Fund has granted a doc.fund to a group of researchers from the Max Perutz Labs, the Faculty of Physics of the University of Vienna, the IMP and the IMBA. The grant is endowed with 1,6 Million Euros and will fund eight PhD positions over four years. Students will be recruited via the Vienna BioCenter PhD Program, and will receive multidisciplinary training to tackle fundamental questions in the field of liquid-liquid phase separation in biology. The doc.fund expects to start recruiting in fall 2021, and is coordinated by Bojan Zagrovic, a computational biologist at the Max Perutz Labs.
Lamins are structural proteins found at the nuclear periphery, where they regulate the mechanical properties of the nucleus and the organization of genetic material within the nucleus. However, they also play a poorly understood role in the nucleoplasm. New work from the lab of Roland Foisner and their collaborators from the Bar Ilan University (Israel) now shows that binding of A-type lamins in the nuclear interior to a protein called LAP2α regulates their mobility and that of surrounding chromatin. The study is published in e-life.
Pluripotent stem cells can give rise to all the different types of specialized cells in the adult organism. Scientists led by Martin Leeb have identified hundreds of genes involved in the exit from naïve pluripotency and show that their activity is largely confined to five key signaling pathways. Their study, published in the EMBO Journal, provides a comprehensive map of the genetic circuits that gate this fundamental cell state transition.
The Max Perutz Labs have established a new doctoral fellowship program that will reward the most ambitious and innovative PhD students at the institute. The program is supported by the University of Vienna and the Medical University of Vienna and covers three fully funded positions per year.
The Max Perutz Labs are rebuilding key parts of the institute. The opening of the new entrance, reception, and study space for students marks a first milestone of a major project.