Konstantina Georgiou, Sara Scinicariello, and Ameya Rakesh Khandekar have been awarded DOC fellowships by the Austrian Academy of Sciences (ÖAW) that will support their PhD projects, which focus on genome organization, protein degradation, and RNA biology respectively.
The proposed function of the centriolar protein Cep97 has to be revised, a new study from the Dammerman lab shows. Rather than just limiting centriole elongation, Cep97 forms a protective roof that ensures that centrioles maintain their correct size once the proper length is reached. The findings are published in “Current Biology” and could help explain how centrioles maintain their size and stability through multiple cell divisions, often throughout the entire lifetime of an organism.
Researchers from the lab of Florian Raible at the Max Perutz Labs and their collaborators have developed an improved tissue clearing and depigmentation method that will help scientists to apply advanced microscopy methods to larger model organisms. The approach, termed “DEEP-Clear” and published in the journal Science Advances, is expected to improve scientists’ ability to study and visualize the whole nervous systems of many different species.
Birthdays should be celebrated, even in challenging times. Last year marked the inaugural celebration of the birthday of Max Perutz, the man who gave the Perutz Labs its name. Unfortunately, preparations for this year´s Max Perutz Day on May 19th were put on ice due to COVID-19. Nevertheless, we did not want this day to pass without celebrating a “virtual Max Perutz Day 2020” online with an outstanding keynote speaker: Jan Löwe, director of the MRC Laboratory of Molecular Biology (LMB) in Cambridge. Jan shared his personal memories of Max Perutz and talked about his own research in the field of structural biology.
Scientists from Sascha Martens Lab at the Max Perutz Labs and their colleagues from the University of Berkeley (USA) have reconstituted the activity of key proteins involved in the growth of autophagosome precursors, a process essential for encapsulating cellular components targeted for degradation and recycling. Their results reveal a previously unknown positive feedback loop and activation mechanism that help explain how the autophagy machinery rapidly generates the autophagosomal membrane. The study is published in the Journal of Cell Biology.
The Max Perutz Labs are embedded in the Vienna Biocenter, providing access to outstanding core facilities shared by all members of the campus in addition to facilities unique to our institute.
With a strong molecular focus and a diversity of model organisms, we aim to bridge basic research with biomedicine.
Cells communicate at every level and molecular misunderstandings must be avoided.
Cracking the genetic code and understanding how it can be corrupted.
Making sense of big data to drive hypothesis-based research.
Visualising the biochemistry of macromolecules in health and disease.
To honour an extraordinary teacher and scientist, the Max Perutz Labs were named after Max Ferdinand Perutz, who, together with John C. Kendrew, was awarded the 1962 Nobel Prize in Chemistry for his studies on the structure of globular proteins ...
The Max Perutz Labs seek to educate students to think critically and analytically, challenge them to set ambitious goals, and instill in them both broad horizons and deep understanding. In doing so, we aspire to furnish them with the necessary knowledge and skills to push forward the frontiers of 21st century biomedical science.