Shotaro Otsuka did his PhD at Kyoto University in Japan with a major in biophysics. For his postdoctoral research he moved to the European Molecular Biology Laboratory EMBL in Heidelberg. In April 2019 he joined the Max Perutz Labs as a junior group leader.
PhD students Henry Thomas and Claudia Pachinger have been awarded the uni:docs Fellowships. Congratulations also to Katharina Siess and Michael Feichtinger on their DOC Fellowships. The prestigious early career programmes are awarded by the University of Vienna and the Austrian Academy of Sciences, providing funding to highly qualified doctoral candidates. The research projects of the awardees will provide insights into biological processes from embryonic stem cell differentiation to the regulation of signalling enzymes.
The Medical University of Vienna has nominated Anete Romanauska as Researcher of the Month. Born in Latvia, she studied Biology in Riga and later in Vienna. She joined Alwin Köhler’s Lab in 2016 as a PhD student. In her research she is interested in the role of lipid metabolism at the nuclear envelope.
Protein Kinase D (PKD) is an enzyme at the heart of many cellular functions. By modifying other proteins, it controls the trafficking of essential cargo in the sorting center of the cell, the Golgi apparatus. During his PhD in Thomas Leonard’s lab, Daniel Elsner has identified a ubiquitin-like domain in PKD that plays a crucial role in its activation. The findings, published in the Journal of Biological Chemistry, revise our understanding of how the “on-switch” of PKD is wired in the cell.
The enzyme CDK8 and its paralog CDK19 are essential modules of the Mediator, a large protein complex that coordinates several key steps in transcription. CDK8 and CDK19 are highly similar and were thought to be functionally redundant. The group of Pavel Kovarik now discovered that CDK8/CDK19 are actually mechanistically distinct and activate different sets of genes in the interferon-induced anti-viral response. The results revise our understanding of anti-viral immunity and could help develop novel therapies of immune disorders. The findings are published in Molecular Cell.
Sebastian Falk has joined the Max Perutz Labs as group leader in March 2019. He is interested in the mechanisms of gene silencing and the regulation of gene expression by small RNAs. A biochemist and structural biologist by training, he received his PhD from Heidelberg University, where he worked on the targeting of membrane proteins. During his Postdoc at the MPI of Biochemistry in Munich he studied eukaroyotic RNA degradation.
The Max Perutz Labs are embedded in the Vienna Biocenter, providing access to outstanding core facilities shared by all members of the campus in addition to facilities unique to our institute.
With a strong molecular focus and a diversity of model organisms, we aim to bridge basic research with biomedicine.
Cells communicate at every level and molecular misunderstandings must be avoided.
Cracking the genetic code and understanding how it can be corrupted.
Making sense of big data to drive hypothesis-based research.
Visualising the biochemistry of macromolecules in health and disease.
To honour an extraordinary teacher and scientist, the Max Perutz Labs were named after Max Ferdinand Perutz, who, together with John C. Kendrew, was awarded the 1962 Nobel Prize in Chemistry for his studies on the structure of globular proteins ...
The Max Perutz Labs seek to educate students to think critically and analytically, challenge them to set ambitious goals, and instill in them both broad horizons and deep understanding. In doing so, we aspire to furnish them with the necessary knowledge and skills to push forward the frontiers of 21st century biomedical science.