The EMC32 will take place at the University of Vienna from 18th to 23rd August 2019. The meeting is co-organized by Max Perutz Labs group leader Kristina Djinovic-Carugo. Talks by international experts will cover the latest technological advances and trends in crystallography and related sciences.
Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists led by Alexander Dammermann at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, now examine how centrioles contribute to this process. The findings, published in “Developmental Cell”, help to elucidate the function of these tiny cellular structures in mitosis.
Upon infection cells manage to quickly switch from normal operation to immune reaction in a matter of minutes. This innate immunity requires a cellular signal cascade that activates antimicrobial or antiviral gene expression. Scientists led by Thomas Decker at the Max Perutz Labs have discovered that an alternative version of the activator of antimicrobial gene expression is constantly present on DNA. A molecular switch between the alternative and the regular version enables a quick onset of the immune response. The findings are published in the journal “Nature Communications”.
The Max Perutz Labs / VDS PhD call opens on July 1st 2019, recruiting students in the fields of RNA Biology, Cell Signalling, or Immunity & Infection. The deadline for application is September 8th, 2019.
Originally from Turkey, Elif Karagöz’s scientific journey brought her to Germany to do her Master’s and to the Netherlands for her PhD at Utrecht University. She then moved to the US where she held a PostDoc position at the University of California at San Francisco. She joined the Max Perutz Labs as a group leader in January 2019 to study stress responses in cells.
Nucleic acids and proteins can be described on different structural levels, but all depend on the most basic - the primary structure. It describes the exact sequence of amino acids or nucleotides – the smallest molecular units that form proteins or RNA and DNA. These units have certain physical and chemical properties, like charge or propensity to interact with water, which ultimately determine the property and, therefore, the function of the whole molecule.
The Max Perutz Labs are embedded in the Vienna Biocenter, providing access to outstanding core facilities shared by all members of the campus in addition to facilities unique to our institute.
With a strong molecular focus and a diversity of model organisms, we aim to bridge basic research with biomedicine.
Cells communicate at every level and molecular misunderstandings must be avoided.
Cracking the genetic code and understanding how it can be corrupted.
Making sense of big data to drive hypothesis-based research.
Visualising the biochemistry of macromolecules in health and disease.
To honour an extraordinary teacher and scientist, the Max Perutz Labs were named after Max Ferdinand Perutz, who, together with John C. Kendrew, was awarded the 1962 Nobel Prize in Chemistry for his studies on the structure of globular proteins ...
The Max Perutz Labs seek to educate students to think critically and analytically, challenge them to set ambitious goals, and instill in them both broad horizons and deep understanding. In doing so, we aspire to furnish them with the necessary knowledge and skills to push forward the frontiers of 21st century biomedical science.