Timing is of the essence
Important biological processes, including feeding and reproduction, rely on accurate timing. Many organisms therefore possess internal clocks that enable them to coordinate their activities with the environment. Adaptation of the organism’s clock, or clocks, is key to survival. A team of Max Perutz Labs scientists, led by Kristin Teßmar-Raible, has identified genes relevant for this adaptation. Intriguingly, a signaling protein that is highly abundant in the brain, calcium/calmodulin-dependent kinase, appears to be the main effector of this adaptation. The results of the study, published in the journal Nature, offer a glimpse into potential molecular candidates for calibrating an organism’s internal clock.