Neurodegenerative diseases like Parkinson’s Disease (PD) pose a major challenge to our aging society. At the Hallacli Lab, we study how toxic protein aggregates, especially alpha-synuclein (α-syn), contribute to disease progression. Our recent work has uncovered a novel connection between α-syn and Processing bodies (P-bodies)—RNA granules that play key roles in RNA metabolism (Hallacli et.al, Cell, 2022). Our goal is to understand how these ancient structures contribute to α-syn-induced toxicity in neurons and how α-syn modulates RNA metabolism in the cell.
The successful candidate will manage day-to-day operations of the lab (ordering, resource management, cell culture organization) but will also assist projects in the lab (iPSC maintenance, routine human neuronal differentiations, etc.). Training and support will be provided for specialized techniques as needed. The balance between organizational responsibilities and experimental work will be adapted based on the candidate’s experience/interests and career goals. The initial contract will be for a year however, a long-term perspective for the position, subject to performance and funding availability, is envisioned. The compensation will be in accordance with the FWF guidelines (Full time is 40 hours/week and minimum CTA level).
Both junior and senior levels of expertise are welcome. The level of independence will depend on prior experience, with increasing responsibility over time. The candidate must have exceptional organizational skills and be a strong communicator and team player. Applicants should have solid theoretical knowledge and practical experience in fundamental molecular and cell biology techniques (molecular cloning, western blotting, fluorescence microscopy etc.). Mammalian cell culture experience is highly encouraged. In the Hallacli Lab, the working language is English, yet command in German language is a plus.
Are you interested? Send your detailed CV showcasing your experimental skills and your lab experience. Please include a motivation letter explaining your background, your interests and your career goals. Include contact details of at least two references. Please write “Lab-Manager 2026” in the subject title and email to erinc.hallacli@maxperutzlabs.ac.at.