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Harnessing plant-soil-microbiome synergy for resilient desert restoration.

2025 iScience;28(11):113748.
PMID:  41234769

Elhady Ahmed, Hirt Heribert

Multimodal learning enables chat-based exploration of single-cell data.

2025 Nature biotechnology
PMID:  41219484

Schaefer Moritz, Peneder Peter, Malzl Daniel, Lombardo Salvo Danilo, Peycheva Mihaela, Burton Jake, Hakobyan Anna, Sharma Varun, Krausgruber Thomas, Sin Celine, Menche Jörg, Tomazou Eleni M, Bock Christoph

A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis.

2025 Science (New York, N.Y.):eadv4257.
PMID:  41196952

Nguyen Tuan-Anh, Lin Jung-Ming G, Marques Anne-Sophie M C, Fottner Maximilian, Bauer Ludwig G, Reicher Andreas, Daum Diana, Scrofani Lorenzo, Liu Yusi, Cheng Carol, D'Angelo L D D Luna, Sanchez Juan, Bueschl Christoph, Marella Nara, Buphamalai Pisanu, Traversi Florian, Bereš Maša, Moll Herwig P, Siklos Marton, Genger Jakob-Wendelin, Hofstaetter Gerald, Villanti Ludovica, Malik Monika, Klimek Christoph, Runggatscher Kathrin, Guertl Bettina, Hansen Jesper S, Dobner Sarah, Babosova Olga, Becirovic Tina, de Rooij Laura P M H, Casanova Emilio, Koren Anna, Froese D Sean, Rosenblatt David S, Klavins Kristaps, Bergthaler Andreas, Menche Jörg, Hannich J Thomas, Abele Miriam, Sdelci Sara, Lang Kathrin, Huber Kilian V M, Kubicek Stefan

Mechanism of autophagy initiation by transmembrane selective autophagy receptors.

2025 The EMBO journal
PMID:  41168463

Adriaenssens Elias, Martens Sascha

A nuclear TRiC/CCT chaperonin assembles meiotic HORMAD proteins into chromosome axes competent for crossing over.

2025 Nature communications;16(1):9411.
PMID:  41136395

Zetka Monique, Pezeshki Amirhossein, Dawson Ryan, Huis In 't Veld Pim J, Jones Steven J M, Silva Nicola

A Comparative Analysis: Molecular Mechanisms of Carbon Catabolite Repression in Bacteria.

2025 Annual review of microbiology;79(1):241, 262, 241-262.
PMID:  41130915

Sonnleitner Elisabeth

Bloom helicase contributes to successful crossover formation with both catalytic and structural roles in Caenorhabditis elegans meiosis.

2025 Nucleic acids research;53(19)
PMID:  41123207

Geetha Sowmya Sivakumar, Čavka Ivana, Dello Stritto Maria Rosaria, Graf Angela, Macha Tomas, Krakolinig Hannah, Köhler Simone, Jantsch Verena

New rhinovirus uncoating intermediate reveals how sodium versus potassium ions influence RNA release.

2025 Scientific reports;15(1):36768.
PMID:  41120457

Real-Hohn Antonio, Blaas Dieter

Visualization of Trypanosoma brucei flagellar pocket collar biogenesis identifies two new cytoskeletal structures.

2025 PLoS biology;23(10):e3003429.
PMID:  41066504

Zelená Marie, Casas Elina, Lambert Chloé, Landrein Nicolas, Dacheux Denis, Bertiaux Eloïse, Abesamis Kim Ivan, Dong Gang, Varga Vladimir, Robinson Derrick Roy, Bonhivers Mélanie

Protein Target Highlights in CASP16: Insights From the Structure Providers.

2025 Proteins
PMID:  41065010

Alexander Leila T, Follonier Océane M, Kryshtafovych Andriy, Abesamis Kim, Bibi-Triki Sabrina, Box Henry G, Breyton Cécile, Bringel Françoise, Carrique Loic, d'Acapito Alessio, Dong Gang, DuBois Rebecca, Fass Deborah, Fiesco Juliana Martinez, Fox Daniel R, Grimes Jonathan M, Grinter Rhys, Jenkins Matthew, Kamyshinsky Roman, Keown Jeremy R, Lackner Gerald, Lammers Michael, Liu Shiheng, Lovering Andrew L, Malinauskas Tomas, Masquida Benoît, Palm Gottfried J, Siebold Christian, Su Tiantian, Zhang Ping, Zhou Z Hong, Fidelis Krzysztof, Topf Maya, Moult John, Schwede Torsten

The distinct roles of genome, methylation, transcription, and translation on protein expression in Arabidopsis thaliana resolve the Central Dogma's information flow.

2025 Genome biology(1)
PMID:  41024265

Zhong Ziming, Bailey Mark, Kim Yong-In, Afsharyan Nazanin P, Parker Briony, Arathoon Louise, Li Xiaowei, Rundle Chelsea A, Behrens Andrew, Nedialkova Danny, Slavov Gancho, Hassani-Pak Keywan, Lilley Kathryn S, Theodoulou Frederica L, Mott Richard

A Novel HMBC-CC-HMQC NMR Strategy for Methyl Assignment Using Triple-C-Labeled α-Ketoisovalerate Integrated with UCBShift 2.0.

2025 Journal of molecular biology:169465.
PMID:  41016549

Knödlstorfer Sonja, Toscano Giorgia, Ptaszek Aleksandra L, Kontaxis Georg, Napoli Federico, Schneider Jakob, Maier Katharina, Kapitonova Anna, Lichtenecker Roman J, Schanda Paul, Konrat Robert

Hxk1 influences expression of metabolic- and virulence-related genes.

2025 mSphere:e0039525.
PMID:  40996045

Wijnants Stefanie, Sofras Dimitrios, Van Genechten Wouter, Vergauwen Rudy, Valle Arevalo Ashley, Gunasekaran Deepika, Ennis Craig L, Jenull Sabrina, Kuchler Karl, Nobile Clarissa J, Van Dijck Patrick

Collective homeostasis of condensation-prone proteins via their mRNAs.

2025 Nature
PMID:  40993389

Faraway Rupert, Costello Heaven Neve, Digby Holly, Kuret Hodnik Klara, Rebselj Jure, Wilkins Oscar G, Chakrabarti Anob M, Iosub Ira A, Vadnjal Neža, Dore Rhys, Knez Lea, Ameres Stefan L, Plaschka Clemens, Ule Jernej

Holliday junction-ZMM protein feedback enables meiotic crossover assurance.

2025 Nature
PMID:  40993383

Henggeler Adrian, Orlić Lucija, Velikov Daniel, Matos Joao

In-depth single molecule localization microscopy using adaptive optics and single objective light-sheet microscopy.

2025 Nature communications;16(1):8362.
PMID:  40993142

Cabillic Marine, Forriere Hisham, Bettarel Laetitia, Butler Corey, Neuhaus Abdelghani, Idrissi Ihssane, Sambrano-Lopez Miguel Edouardo, Rossbroich Julian, Müller Lucas-Raphael, Ries Jonas, Grenci Gianluca, Viasnoff Virgile, Levet Florian, Sibarita Jean-Baptiste, Galland Rémi

Separable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance.

2025 bioRxiv : the preprint server for biology
PMID:  40964333

Shang Renfu, Popitsch Niko, Lee Seungjae, Ameres Stefan L, Lai Eric C

Artificial Intelligence and Network Medicine: Path to Precision Medicine.

2025 NEJM AI;2(9)
PMID:  40918693

Altucci Lucia, Badimon Lina, Balligand Jean-Luc, Baumbach Jan, Catapano Alberico L, Cheng Feixong, DeMeo Dawn, Gupta Rajat, Hacker Marcus, Liu Yang-Yu, Loscalzo Joseph, Maniscalco Sabrina, Menche Jörg, Menichetti Giulia, Parini Paolo, Schmidt Harald H H W, Zitnik Marinka

Translon: a single term for translated regions.

2025 Nature methods
PMID:  40890551

Świrski Michał I, Tierney Jack A S, Albà M Mar, Andreev Dmitry E, Aspden Julie L, Atkins John F, Bassani-Sternberg Michal, Berry Marla J, Biffo Stefano, Boris-Lawrie Kathleen, Borodovsky Mark, Brierley Ian, Brook Matthew, Brunet Marie A, Bujnicki Janusz M, Caliskan Neva, Calviello Lorenzo, Carvunis Anne-Ruxandra, Cate Jamie H D, Cenik Can, Chang Kung Yao, Chen Yiwen, Chothani Sonia, Choudhary Jyoti S, Clark Patricia L, Clauwaert Jim, Cooley Lynn, Dassi Erik, Dean Kellie, Diaz Jean-Jacques, Dieterich Christoph, Dikstein Rivka, Dinman Jonathan D, Dmitriev Sergey E, Dontsova Olga A, Dunham Christine M, Eswarappa Sandeep M, Farabaugh Philip J, Faridi Pouya, Fierro-Monti Ivo, Firth Andrew E, Gatfield David, Gebauer Fátima, Gelfand Mikhail S, Gray Nicola K, Green Rachel, Hill Chris H, Hou Ya-Ming, Hübner Norbert, Ignatova Zoya, Ivanov Pavel, Iwasaki Shintaro, Johnson Rory, Jomaa Ahmad, Jovanovic Marko, Jungreis Irwin, Kellis Manolis, Kieft Jeffrey S, Kochetov Alex V, Koonin Eugene V, Korostelev Andrei A, Kufel Joanna, Kulakovskiy Ivan V, Kurian Leo, Lafontaine Denis L J, Larsson Ola, Loughran Gary, Lukeš Julius, Mariotti Marco, Martens-Uzunova Elena S, Martinez Thomas F, Matsumoto Akinobu, McManus Joel, Medenbach Jan, Melnikov Sergey V, Menschaert Gerben, Merchante Catharina, Mikl Martin, Miller W Allen, Mühlemann Oliver, Namy Olivier, Nedialkova Danny D, Nosek Jozef, Orchard Sandra, Ozretić Petar, Pertea Mihaela, Pervouchine Dmitri D, Romão Luísa, Ron David, Roucou Xavier, Rubtsova Maria P, Ruiz-Orera Jorge, Saghatelian Alan, Salzberg Steven L, Seale Lucia A, Seoighe Cathal, Sergiev Petr V, Shah Premal, Shirokikh Nikolay, Slavoff Sarah A, Sonenberg Nahum, Stasevich Timothy J, Szczesny Roman J, Tamm Tiina, Tchórzewski Marek, Topisirovic Ivan, Tremblay Michel L, Tuller Tamir, Ulitsky Igor, Valášek Leoš Shivaya, Van Damme Petra, Viero Gabriella, Vizcaino Juan Antonio, Vogel Christine, Wallace Edward W J, Weissman Jonathan S, Westhof Eric, Whiffin Nicola, Wilson Daniel N, Xie Zhi, Yewdell Jonathan W, Yordanova Martina M, Yu Chien-Hung, Yurchenko Vyacheslav, Zagrovic Bojan, Valen Eivind, Baranov Pavel V

A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles.

2025 Cell
PMID:  40876457

Grabarczyk Daniel B, Aird Eric J, Reznikow Vanessa, Kirchgatterer Paul C, Ehrmann Julian F, Kurzbauer Robert, Bell Lillie E, Kellner Max J, Aggarwal Ritika, Schleiffer Alexander, Faas Victoria, Deszcz Luiza, Meinhart Anton, Versteeg Gijs A, Penninger Josef M, Stelzl Lukas S, Gaidt Moritz M, Tessmer Ingrid, Corn Jacob E, Clausen Tim

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