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A conformation-specific ON-switch for controlling CAR T cells with an orally available drug.

2020 Proceedings of the National Academy of Sciences of the United States of America;117(26):14926, 14935, 14926-14935.
PMID:  32554495

Zajc Charlotte U, Dobersberger Markus, Schaffner Irene, Mlynek Georg, Pühringer Dominic, Salzer Benjamin, Djinović-Carugo Kristina, Steinberger Peter, De Sousa Linhares Annika, Yang Nicole J, Obinger Christian, Holter Wolfgang, Traxlmayr Michael W, Lehner Manfred

Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C.

2020 Communications biology;3(1):253.
PMID:  32444788

Reimann Lena, Schwäble Anja N, Fricke Anna L, Mühlhäuser Wignand W D, Leber Yvonne, Lohanadan Keerthika, Puchinger Martin G, Schäuble Sascha, Faessler Erik, Wiese Heike, Reichenbach Christa, Knapp Bettina, Peikert Christian D, Drepper Friedel, Hahn Udo, Kreutz Clemens, van der Ven Peter F M, Radziwill Gerald, Djinović-Carugo Kristina, Fürst Dieter O, Warscheid Bettina

Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation.

2020 ACS catalysis;10(10):5405, 5418, 5405-5418.
PMID:  32440366

Michlits Hanna, Lier Bettina, Pfanzagl Vera, Djinović-Carugo Kristina, Furtmüller Paul G, Oostenbrink Chris, Obinger Christian, Hofbauer Stefan

Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.

2020 Proceedings of the National Academy of Sciences of the United States of America;117(1):317, 327, 317-327.
PMID:  31852826

Trstenjak Nikolina, Milić Dalibor, Graewert Melissa A, Rouha Harald, Svergun Dmitri, Djinović-Carugo Kristina, Nagy Eszter, Badarau Adriana

Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase.

2020 The FEBS journal;287(13):2779, 2796, 2779-2796.
PMID:  31794133

Hofbauer Stefan, Helm Johannes, Obinger Christian, Djinović-Carugo Kristina, Furtmüller Paul G

Redox Cofactor Rotates during Its Stepwise Decarboxylation: Molecular Mechanism of Conversion of Coproheme to Heme .

2019 ACS catalysis;9(8):6766, 6782, 6766-6782.
PMID:  31423350

Milazzo Lisa, Gabler Thomas, Pühringer Dominic, Jandova Zuzana, Maresch Daniel, Michlits Hanna, Pfanzagl Vera, Djinović-Carugo Kristina, Oostenbrink Chris, Furtmüller Paul G, Obinger Christian, Smulevich Giulietta, Hofbauer Stefan

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C.

2019 Science advances;5(5):eaav8421.
PMID:  31131323

Collier Miranda P, Alderson T Reid, de Villiers Carin P, Nicholls Daisy, Gastall Heidi Y, Allison Timothy M, Degiacomi Matteo T, Jiang He, Mlynek Georg, Fürst Dieter O, van der Ven Peter F M, Djinovic-Carugo Kristina, Baldwin Andrew J, Watkins Hugh, Gehmlich Katja, Benesch Justin L P

Protective properties of the cultured stem cell proteome studied in an animal model of acetaminophen-induced acute liver failure.

2019 Molecular biology reports;46(3):3101, 3112, 3101-3112.
PMID:  30977085

Temnov Andrey Alexandrovich, Rogov Konstantin Arkadevich, Sklifas Alla Nikolaevna, Klychnikova Elena Valerievna, Hartl Markus, Djinovic-Carugo Kristina, Charnagalov Alexej

Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage.

2018 The Journal of biological chemistry;293(38):14823, 14838, 14823-14838.
PMID:  30072383

Pfanzagl Vera, Nys Kevin, Bellei Marzia, Michlits Hanna, Mlynek Georg, Battistuzzi Gianantonio, Djinovic-Carugo Kristina, Van Doorslaer Sabine, Furtmüller Paul G, Hofbauer Stefan, Obinger Christian

Secreted heme peroxidase from : Insights into catalysis, structure, and biological role.

2018 The Journal of biological chemistry;293(4):1330, 1345, 1330-1345.
PMID:  29242189

Nicolussi Andrea, Dunn Joe Dan, Mlynek Georg, Bellei Marzia, Zamocky Marcel, Battistuzzi Gianantonio, Djinović-Carugo Kristina, Furtmüller Paul G, Soldati Thierry, Obinger Christian

Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies.

2017 ACS catalysis;7(11):7962, 7976, 7962-7976.
PMID:  29142780

Schaffner Irene, Mlynek Georg, Flego Nicola, Pühringer Dominic, Libiseller-Egger Julian, Coates Leighton, Hofbauer Stefan, Bellei Marzia, Furtmüller Paul G, Battistuzzi Gianantonio, Smulevich Giulietta, Djinović-Carugo Kristina, Obinger Christian

A novel non-canonical PIP-box mediates PARG interaction with PCNA.

2017 Nucleic acids research;45(16):9741, 9759, 9741-9759.
PMID:  28934471

Kaufmann Tanja, Grishkovskaya Irina, Polyansky Anton A, Kostrhon Sebastian, Kukolj Eva, Olek Karin M, Herbert Sebastien, Beltzung Etienne, Mechtler Karl, Peterbauer Thomas, Gotzmann Josef, Zhang Lijuan, Hartl Markus, Zagrovic Bojan, Elsayad Kareem, Djinovic-Carugo Kristina, Slade Dea

Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 Å crystal structure of the complex.

2017 mAbs;9(7):1088, 1104, 1088-1104.
PMID:  28816592

Lobner Elisabeth, Humm Anne-Sophie, Mlynek Georg, Kubinger Konstantin, Kitzmüller Michael, Traxlmayr Michael W, Djinović-Carugo Kristina, Obinger Christian

Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains.

2017 Scientific reports;7(1):3993.
PMID:  28638118

Puž Vid, Pavšič Miha, Lenarčič Brigita, Djinović-Carugo Kristina

Bacterial protease uses distinct thermodynamic signatures for substrate recognition.

2017 Scientific reports;7(1):2848.
PMID:  28588213

Bezerra Gustavo Arruda, Ohara-Nemoto Yuko, Cornaciu Irina, Fedosyuk Sofiya, Hoffmann Guillaume, Round Adam, Márquez José A, Nemoto Takayuki K, Djinović-Carugo Kristina

Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies.

2017 Structure (London, England : 1993);25(6):878, 889.e5, 878-889.e5.
PMID:  28528777

Lobner Elisabeth, Humm Anne-Sophie, Göritzer Kathrin, Mlynek Georg, Puchinger Martin G, Hasenhindl Christoph, Rüker Florian, Traxlmayr Michael W, Djinović-Carugo Kristina, Obinger Christian

Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation.

2017 The Journal of biological chemistry;292(20):8244, 8261, 8244-8261.
PMID:  28348079

Grishkovskaya Irina, Paumann-Page Martina, Tscheliessnig Rupert, Stampler Johanna, Hofbauer Stefan, Soudi Monika, Sevcnikar Benjamin, Oostenbrink Chris, Furtmüller Paul G, Djinović-Carugo Kristina, Nauseef William M, Obinger Christian

Deciphering the BAR code of membrane modulators.

2017 Cellular and molecular life sciences : CMLS;74(13):2413, 2438, 2413-2438.
PMID:  28243699

Salzer Ulrich, Kostan Julius, Djinović-Carugo Kristina

α-Actinin/titin interaction: A dynamic and mechanically stable cluster of bonds in the muscle Z-disk.

2017 Proceedings of the National Academy of Sciences of the United States of America;114(5):1015, 1020, 1015-1020.
PMID:  28096424

Grison Marco, Merkel Ulrich, Kostan Julius, Djinović-Carugo Kristina, Rief Matthias

Human cytomegalovirus phosphoproteins are hypophosphorylated and intrinsically disordered.

2017 The Journal of general virology;98(3):471, 485, 471-485.
PMID:  27959783

Rieder Franz J J, Kastner Marie-Theres, Hartl Markus, Puchinger Martin G, Schneider Martina, Majdic Otto, Britt William J, Djinović-Carugo Kristina, Steininger Christoph

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