Molecular insights into the premature aging disease progeria.
Vidak Sandra, Foisner Roland
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Gesson Kevin, Rescheneder Philipp, Skoruppa Michael P, von Haeseler Arndt, Dechat Thomas, Foisner Roland
Degradation-mediated protein quality control at the inner nuclear membrane.
Boban Mirta, Foisner Roland
Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes.
Loi Manuela, Cenni Vittoria, Duchi Serena, Squarzoni Stefano, Lopez-Otin Carlos, Foisner Roland, Lattanzi Giovanna, Capanni Cristina
Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins.
Vidak Sandra, Kubben Nard, Dechat Thomas, Foisner Roland
Loss of lamin A function increases chromatin dynamics in the nuclear interior.
Bronshtein I, Kepten E, Kanter I, Berezin S, Lindner M, Redwood Abena B, Mai S, Gonzalo S, Foisner R, Shav-Tal Y, Garini Y
Lamins at the crossroads of mechanosignaling.
Osmanagic-Myers Selma, Dechat Thomas, Foisner Roland
Atypical ubiquitylation in yeast targets lysine-less Asi2 for proteasomal degradation.
Boban Mirta, Ljungdahl Per O, Foisner Roland
A nuclear ubiquitin-proteasome pathway targets the inner nuclear membrane protein Asi2 for degradation.
Boban Mirta, Pantazopoulou Marina, Schick Anna, Ljungdahl Per O, Foisner Roland
Lamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biology.
Brachner Andreas, Foisner Roland
Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease.
Gesson Kevin, Vidak Sandra, Foisner Roland
The muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair the functions of the nucleoplasmic lamin-A/C-LAP2α complex in mice.
Pilat Ursula, Dechat Thomas, Bertrand Anne T, Woisetschläger Nikola, Gotic Ivana, Spilka Rita, Biadasiewicz Katarzyna, Bonne Gisèle, Foisner Roland
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo.
Brachner Andreas, Braun Juliane, Ghodgaonkar Medini, Castor Dennis, Zlopasa Livija, Ehrlich Veronika, Jiricny Josef, Gotzmann Josef, Knasmüller Siegfried, Foisner Roland
Evolvement of LEM proteins as chromatin tethers at the nuclear periphery.
Brachner Andreas, Foisner Roland
Multiple novel functions of lamina associated polypeptide 2α in striated muscle.
Gotic Ivana, Foisner Roland
Lamina-independent lamins in the nuclear interior serve important functions.
Dechat T, Gesson K, Foisner R
Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W.
Roblek Marko, Schüchner Stefan, Huber Veronika, Ollram Katrin, Vlcek-Vesely Sylvia, Foisner Roland, Wehnert Manfed, Ogris Egon
Lamins: 'structure goes cycling'.
Boban Mirta, Braun Juliane, Foisner Roland
Loss of LAP2 alpha delays satellite cell differentiation and affects postnatal fiber-type determination.
Gotic Ivana, Schmidt Wolfgang M, Biadasiewicz Katarzyna, Leschnik Michael, Spilka Rita, Braun Juliane, Stewart Colin L, Foisner Roland
Lamina-associated polypeptide 2alpha loss impairs heart function and stress response in mice.
Gotic Ivana, Leschnik Michael, Kolm Ursula, Markovic Mato, Haubner Bernhard J, Biadasiewicz Katarzyna, Metzler Bernhard, Stewart Colin L, Foisner Roland