Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Rajsbaum Ricardo, Versteeg Gijs A, Schmid Sonja, Maestre Ana M, Belicha-Villanueva Alan, Martínez-Romero Carles, Patel Jenish R, Morrison Juliet, Pisanelli Giuseppe, Miorin Lisa, Laurent-Rolle Maudry, Moulton Hong M, Stein David A, Fernandez-Sesma Ana, tenOever Benjamin R, García-Sastre Adolfo
TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity.
Rajsbaum Ricardo, García-Sastre Adolfo, Versteeg Gijs A
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.
Versteeg Gijs A, Rajsbaum Ricardo, Sánchez-Aparicio Maria Teresa, Maestre Ana M, Valdiviezo Julio, Shi Mude, Inn Kyung-Soo, Fernandez-Sesma Ana, Jung Jae, García-Sastre Adolfo
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Mata Miguel A, Satterly Neal, Versteeg Gijs A, Frantz Doug, Wei Shuguang, Williams Noelle, Schmolke Mirco, Peña-Llopis Samuel, Brugarolas James, Forst Christian V, White Michael A, García-Sastre Adolfo, Roth Michael G, Fontoura Beatriz M A