Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex.
Wienerroither Sebastian, Shukla Priyank, Farlik Matthias, Majoros Andrea, Stych Bernadette, Vogl Claus, Cheon HyeonJoo, Stark George R, Strobl Birgit, Müller Mathias, Decker Thomas
Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.
Rauch Isabella, Rosebrock Felix, Hainzl Eva, Heider Susanne, Majoros Andrea, Wienerroither Sebastian, Strobl Birgit, Stockinger Silvia, Kenner Lukas, Müller Mathias, Decker Thomas
Tracking heavy water (D2O) incorporation for identifying and sorting active microbial cells.
Berry David, Mader Esther, Lee Tae Kwon, Woebken Dagmar, Wang Yun, Zhu Di, Palatinszky Marton, Schintlmeister Arno, Schmid Markus C, Hanson Buck T, Shterzer Naama, Mizrahi Itzhak, Rauch Isabella, Decker Thomas, Bocklitz Thomas, Popp Jürgen, Gibson Christopher M, Fowler Patrick W, Huang Wei E, Wagner Michael
STAT1 plays a role in TLR signal transduction and inflammatory responses.
Luu Kevin, Greenhill Claire J, Majoros Andrea, Decker Thomas, Jenkins Brendan J, Mansell Ashley
Type I interferons have opposing effects during the emergence and recovery phases of colitis.
Rauch Isabella, Hainzl Eva, Rosebrock Felix, Heider Susanne, Schwab Clarissa, Berry David, Stoiber Dagmar, Wagner Michael, Schleper Christa, Loy Alexander, Urich Tim, Müller Mathias, Strobl Birgit, Kenner Lukas, Decker Thomas
Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway.
Hansen Kathrine, Prabakaran Thaneas, Laustsen Anders, Jørgensen Sofie E, Rahbæk Stine H, Jensen Søren B, Nielsen Rikke, Leber Jess H, Decker Thomas, Horan Kristy A, Jakobsen Martin R, Paludan Søren R
STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.
Semper Christian, Leitner Nicole R, Lassnig Caroline, Parrini Matthias, Mahlakõiv Tanel, Rammerstorfer Michael, Lorenz Karin, Rigler Doris, Müller Simone, Kolbe Thomas, Vogl Claus, Rülicke Thomas, Staeheli Peter, Decker Thomas, Müller Mathias, Strobl Birgit
Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery.
Schwab Clarissa, Berry David, Rauch Isabella, Rennisch Ina, Ramesmayer Julia, Hainzl Eva, Heider Susanne, Decker Thomas, Kenner Lukas, Müller Mathias, Strobl Birgit, Wagner Michael, Schleper Christa, Loy Alexander, Urich Tim
Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.
Wienerroither Sebastian, Rauch Isabella, Rosebrock Felix, Jamieson Amanda M, Bradner James, Muhar Matthias, Zuber Johannes, Müller Mathias, Decker Thomas
The regulation of inflammation by interferons and their STATs.
Rauch Isabella, Müller Mathias, Decker Thomas
Route of Infection Determines the Impact of Type I Interferons on Innate Immunity to Listeria monocytogenes.
Kernbauer Elisabeth, Maier Verena, Rauch Isabella, Müller Mathias, Decker Thomas
Role of tissue protection in lethal respiratory viral-bacterial coinfection.
Jamieson Amanda M, Pasman Lesley, Yu Shuang, Gamradt Pia, Homer Robert J, Decker Thomas, Medzhitov Ruslan
Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection.
Kernbauer Elisabeth, Maier Verena, Stoiber Dagmar, Strobl Birgit, Schneckenleithner Christine, Sexl Veronika, Reichart Ursula, Reizis Boris, Kalinke Ulrich, Jamieson Amanda, Müller Mathias, Decker Thomas
Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.
Farlik Matthias, Rapp Birgit, Marie Isabelle, Levy David E, Jamieson Amanda M, Decker Thomas
LipA, a tyrosine and lipid phosphatase involved in the virulence of Listeria monocytogenes.
Kastner Renate, Dussurget Olivier, Archambaud Cristel, Kernbauer Elisabeth, Soulat Didier, Cossart Pascale, Decker Thomas
Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling.
Bourgeois Christelle, Majer Olivia, Frohner Ingrid E, Lesiak-Markowicz Iwona, Hildering Kwang-Soo, Glaser Walter, Stockinger Silvia, Decker Thomas, Akira Shizuo, Müller Mathias, Kuchler Karl
Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression.
Farlik Matthias, Reutterer Benjamin, Schindler Christian, Greten Florian, Vogl Claus, Müller Mathias, Decker Thomas
Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.
Pilz Andreas, Kratky Wolfgang, Stockinger Silvia, Simma Olivia, Kalinke Ulrich, Lingnau Karen, von Gabain Alexander, Stoiber Dagmar, Sexl Veronika, Kolbe Thomas, Rülicke Thomas, Müller Mathias, Decker Thomas
Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes.
Stockinger Silvia, Kastner Renate, Kernbauer Elisabeth, Pilz Andreas, Westermayer Sandra, Reutterer Benjamin, Soulat Didier, Stengl Gabriele, Vogl Claus, Frenz Theresa, Waibler Zoe, Taniguchi Tadatsugu, Rülicke Thomas, Kalinke Ulrich, Müller Mathias, Decker Thomas
Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes.
Stockinger Silvia, Decker Thomas