Inducible dCas12a system expands CRISPRi/a capabilities for functional genomics in malaria parasite .
Lucky Amuza Byaruhanga, Li XiaoLian, Kobakhidze George, Gonzales Jose Lulo, Wang Chengqi, Cui Liwang, Dong Gang, Miao Jun
Mechanism of activation of an ancestral TEC kinase by PIP.
Krötenheerdt Eva, Piëch Lucas, von Raußendorf Freia, Reinhardt Ronja, Nataraj Ranjana, Wedige Nicholas, Nyvall Hunter G, Walsh Emma E, Burke John E, Leonard Thomas A
Mechanism of spliceosome termination.
Boreikaite Vytaute, Faraway Rupert, Vorländer Matthias K, Phillips Alexander W, Opitz Leonie, Wanke Moritz, Yakoub George, Raffl Gerald, Fin Laura, González-Prieto Román, Luijsterburg Martijn S, Ameres Stefan L, Plaschka Clemens
Modeling Protein Diffusion Across ER-Nuclear Envelope Junctions Reveals Efficient Transport via Simple Diffusion.
Moschella Carmela, Scholz Julia, Merino-Aceituno Sara, Schmeiser Christian, Otsuka Shotaro
Chromatin remodeling coordinates chromosome compaction, synaptonemal complex architecture and meiotic crossing-over.
Palmer Nathan, Khauratovich Uladzislava, Toe Laurine Dal, Hartmann Felix, Pavlova Anzhela, Khanal Sushil, Patel Rajvi, Petroulaki Vasiliki, Bláhová Viktoria, Hunter Neil, Robert Thomas, Goloborodko Anton, Matos Joao
A lipid transfer-dependent feedback loop activates ATG9A compartments in autophagy initiation.
Holzer Elisabeth, Sawa-Makarska Justyna, Bernklau Daniel, Romanov Julia, Schuschnig Martina, Martens Sascha
Mutations in SUMO conjugating enzyme reveal contributions of sumoylation to plant stress resilience and yield.
Nehlin Lilian, Alam Sadia Sabrina, Shehzad Junaid, Ijaz Bushra, Julián Jose, Winter Nikola, Bachmair Andreas
Transposon end recognition and excision mechanisms of type I-F CRISPR-associated transposases.
Walter Mateusz, Finocchio Giada, Oberli Seraina, Hammerschmid Iana C, Lampe George D, Karan Julia, Swartjes Thomas, Sternberg Samuel H, Jinek Martin, Querques Irma
[Not Available].
Hermisson Joachim, Schreiner Claudia, Weichselbaumer Stefanie, Werner Marlene, Hackl Verena, Roth Jacob, Leiss Sandra, Maukner Anna Christina, Wojczewski Silvia, Hainzl Astrid, Hermisson Sabine, Thonhofer Kevin, Pleschberger Sabine, Hoffmann Kathryn
Ashwin and FAM98 paralogs define nuclear and cytoplasmic RNA ligase complexes for tRNA biogenesis.
Kleinwächter Moritz, Moser Marius, Raynaud Nathan, Pfleiderer Moritz M, Jinek Martin, Martinez Javier
Structural framework for the assembly of the human tRNA ligase complex.
Pfleiderer Moritz M, Kleinwächter Moritz, Nievergelt Ajse S, Boneberg Franziska M, Kroupova Alena, Martinez Javier, Jinek Martin
A complex of MAST1 and 14-3-3η regulates Tau phosphorylation in the developing cortex.
Antonioli Sumire, Heisterkamp Patrick, Chen Weiqiang, Anrather Dorothea, Hartl Markus, Martinez-Reza Maria Fernanda, Tripathy Ratna, Schutzbier Michael, Mechtler Karl, Keays David A, Leonard Thomas A
Antifungal drug resistance in Candida auris: molecular mechanisms and emerging therapeutic approaches.
Phan-Canh Trinh, Elbe-Bürger Adelheid, Kuchler Karl
Interferon family feud determines immunity to mycobacteria.
Babadei Olga, Decker Thomas
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy.
Duan Yongjia, Lu Ye, Paul Sanjoy, Betz Johannes, Wilhelm Léa P, Cook Annan S I, Ren Xuefeng, Adriaenssens Elias, Martens Sascha, Ganley Ian G, Hummer Gerhard, Hurley James H
Modifications of Lysine Residues 294 and 311 Within the Microtubule-Binding Region Alter Tau Aggregation and Tubulin Binding Equilibria.
Vogl Dominik P, Migotti Mario, Konrat Robert, Conibear Anne C, Becker Christian F W
An evolutionarily conserved N-terminal domain of RRF-3 governs GTSF-1 binding in nematodes.
Govind Shamitha, Ruppert Sebastian, Kirangwa Joseph, Busetto Virginia, Nischwitz Emily, Almeida Miguel Vasconcelos, Hellmann Svenja, Witte Hahn, Sommer Ralf J, Butter Falk, Falk Sebastian, Sarkies Peter, Ketting René F
Decoding BIG: how one protein influences multiple pathways.
Theodoulou Frederica L, Grabarczyk Daniel B, Clausen Tim, Bachmair Andreas
Regulation and roles of mammalian mitophagy.
Martens Sascha, Ganley Ian G
The ZBTB16/CUL3/ROC1 ubiquitin ligase drives the degradation of pathogenic pendrin (SLC26A4) protein variants.
Huber Florian, Bernardinelli Emanuele, Haddad Bassam G, Klaus Sophie, Weitgasser Lennart, Roesch Sebastian, Jakab Martin, Konrat Robert, Machtens Jan-Philipp, Eladari Dominique, Dossena Silvia