Functional analyses of the CIF1-CIF2 complex in trypanosomes identify the structural motifs required for cytokinesis.
Hu Huiqing, Majneri Paul, Li Dielan, Kurasawa Yasuhiro, An Tai, Dong Gang, Li Ziyin
The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.
Khunweeraphong Narakorn, Stockner Thomas, Kuchler Karl
A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.
Newby Gregory A, Kiriakov Szilvia, Hallacli Erinc, Kayatekin Can, Tsvetkov Peter, Mancuso Christopher P, Bonner J Maeve, Hesse William R, Chakrabortee Sohini, Manogaran Anita L, Liebman Susan W, Lindquist Susan, Khalil Ahmad S
Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Gonzalez Grecia M, Durica-Mitic Svetlana, Hardwick Steven W, Moncrieffe Martin C, Resch Marcus, Neumann Piotr, Ficner Ralf, Görke Boris, Luisi Ben F
An unfolded protein-induced conformational switch activates mammalian IRE1.
Karagöz G Elif, Acosta-Alvear Diego, Nguyen Hieu T, Lee Crystal P, Chu Feixia, Walter Peter
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Elling Ulrich, Wimmer Reiner A, Leibbrandt Andreas, Burkard Thomas, Michlits Georg, Leopoldi Alexandra, Micheler Thomas, Abdeen Dana, Zhuk Sergei, Aspalter Irene M, Handl Cornelia, Liebergesell Julia, Hubmann Maria, Husa Anna-Maria, Kinzer Manuela, Schuller Nicole, Wetzel Ellen, van de Loo Nina, Martinez Jorge Arturo Zepeda, Estoppey David, Riedl Ralph, Yang Fengtang, Fu Beiyuan, Dechat Thomas, Ivics Zoltán, Agu Chukwuma A, Bell Oliver, Blaas Dieter, Gerhardt Holger, Hoepfner Dominic, Stark Alexander, Penninger Josef M
MazF activation promotes translational heterogeneity of the mRNA in populations.
Nikolic Nela, Didara Zrinka, Moll Isabella
Thiol-linked alkylation of RNA to assess expression dynamics.
Herzog Veronika A, Reichholf Brian, Neumann Tobias, Rescheneder Philipp, Bhat Pooja, Burkard Thomas R, Wlotzka Wiebke, von Haeseler Arndt, Zuber Johannes, Ameres Stefan L
Redox state-dependent modulation of plant SnRK1 kinase activity differs from AMPK regulation in animals.
Wurzinger Bernhard, Mair Andrea, Fischer-Schrader Katrin, Nukarinen Ella, Roustan Valentin, Weckwerth Wolfram, Teige Markus
A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Kaufmann Tanja, Grishkovskaya Irina, Polyansky Anton A, Kostrhon Sebastian, Kukolj Eva, Olek Karin M, Herbert Sebastien, Beltzung Etienne, Mechtler Karl, Peterbauer Thomas, Gotzmann Josef, Zhang Lijuan, Hartl Markus, Zagrovic Bojan, Elsayad Kareem, Djinovic-Carugo Kristina, Slade Dea
A novel mechanism of antibody-mediated enhancement of flavivirus infection.
Haslwanter Denise, Blaas Dieter, Heinz Franz X, Stiasny Karin
The SmAP2 RNA binding motif in the 3'UTR affects mRNA stability in the crenarchaeum Sulfolobus solfataricus.
Märtens Birgit, Sharma Kundan, Urlaub Henning, Bläsi Udo
Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design.
Geist Leonhard, Mayer Moriz, Cockcroft Xiao-Ling, Wolkerstorfer Bernhard, Kessler Dirk, Engelhardt Harald, McConnell Darryl B, Konrat Robert
ICTV Virus Taxonomy Profile: Picornaviridae.
Zell R, Delwart E, Gorbalenya A E, Hovi T, King A M Q, Knowles N J, Lindberg A M, Pallansch M A, Palmenberg A C, Reuter G, Simmonds P, Skern T, Stanway G, Yamashita T
Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
Falk Sebastian, Tants Jan-Niklas, Basquin Jerôme, Thoms Matthias, Hurt Ed, Sattler Michael, Conti Elena
Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase.
Falk Sebastian, Bonneau Fabien, Ebert Judith, Kögel Alexander, Conti Elena
A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding.
Kostrhon Sebastian, Kontaxis Georg, Kaufmann Tanja, Schirghuber Erika, Kubicek Stefan, Konrat Robert, Slade Dea
Anthranilic acid, the new player in the ensemble of aromatic residue labeling precursor compounds.
Schörghuber Julia, Geist Leonhard, Bisaccia Marilena, Weber Frederik, Konrat Robert, Lichtenecker Roman J
Changes in Pro-Inflammatory Markers in Detoxifying Chronic Alcohol Abusers, Divided by Lesch Typology, Reflect Cognitive Dysfunction.
Hanak Catherine, Benoit Janaina, Fabry Lauriane, Hein Matthieu, Verbanck Paul, de Witte Philippe, Walter Henriette, Dexter David T, Ward Roberta J
Interaction of 2A proteinase of human rhinovirus genetic group A with eIF4E is required for eIF4G cleavage during infection.
Aumayr Martina, Schrempf Anna, Üzülmez Öykü, Olek Karin M, Skern Tim