Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design.
Geist Leonhard, Mayer Moriz, Cockcroft Xiao-Ling, Wolkerstorfer Bernhard, Kessler Dirk, Engelhardt Harald, McConnell Darryl B, Konrat Robert
A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding.
Kostrhon Sebastian, Kontaxis Georg, Kaufmann Tanja, Schirghuber Erika, Kubicek Stefan, Konrat Robert, Slade Dea
Anthranilic acid, the new player in the ensemble of aromatic residue labeling precursor compounds.
Schörghuber Julia, Geist Leonhard, Bisaccia Marilena, Weber Frederik, Konrat Robert, Lichtenecker Roman J
Highly Selective Stable Isotope Labeling of Histidine Residues by Using a Novel Precursor in E. coli-Based Overexpression Systems.
Schörghuber Julia, Geist Leonhard, Platzer Gerald, Konrat Robert, Lichtenecker Roman J
RNA binding and chaperone activity of the E. coli cold-shock protein CspA.
Rennella Enrico, Sára Tomáš, Juen Michael, Wunderlich Christoph, Imbert Lionel, Solyom Zsofia, Favier Adrien, Ayala Isabel, Weinhäupl Katharina, Schanda Paul, Konrat Robert, Kreutz Christoph, Brutscher Bernhard
Calcium-dependent binding of Myc to calmodulin.
Raffeiner Philipp, Schraffl Andrea, Schwarz Thomas, Röck Ruth, Ledolter Karin, Hartl Markus, Konrat Robert, Stefan Eduard, Bister Klaus
Investigation of Intrinsically Disordered Proteins through Exchange with Hyperpolarized Water.
Kurzbach Dennis, Canet Estel, Flamm Andrea G, Jhajharia Aditya, Weber Emmanuelle M M, Konrat Robert, Bodenhausen Geoffrey
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Wrasidlo Wolfgang, Tsigelny Igor F, Price Diana L, Dutta Garima, Rockenstein Edward, Schwarz Thomas C, Ledolter Karin, Bonhaus Douglas, Paulino Amy, Eleuteri Simona, Skjevik Åge A, Kouznetsova Valentina L, Spencer Brian, Desplats Paula, Gonzalez-Ruelas Tania, Trejo-Morales Margarita, Overk Cassia R, Winter Stefan, Zhu Chunni, Chesselet Marie-Francoise, Meier Dieter, Moessler Herbert, Konrat Robert, Masliah Eliezer
Filterable Agents for Hyperpolarization of Water, Metabolites, and Proteins.
Vuichoud Basile, Bornet Aurélien, de Nanteuil Florian, Milani Jonas, Canet Estel, Ji Xiao, Miéville Pascal, Weber Emmanuelle, Kurzbach Dennis, Flamm Andrea, Konrat Robert, Gossert Alvar D, Jannin Sami, Bodenhausen Geoffrey
Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy.
Juen Michael Andreas, Wunderlich Christoph Hermann, Nußbaumer Felix, Tollinger Martin, Kontaxis Georg, Konrat Robert, Hansen D Flemming, Kreutz Christoph
Five and four dimensional experiments for robust backbone resonance assignment of large intrinsically disordered proteins: application to Tau3x protein.
Żerko Szymon, Byrski Piotr, Włodarczyk-Pruszyński Paweł, Górka Michał, Ledolter Karin, Masliah Eliezer, Konrat Robert, Koźmiński Wiktor
1H, 15N, 13C resonance assignment of human GAP-43.
Flamm Andrea Gabriele, Żerko Szymon, Zawadzka-Kazimierczuk Anna, Koźmiński Wiktor, Konrat Robert, Coudevylle Nicolas
Biochemical and Structural Characterization of the Interaction between the Siderocalin NGAL/LCN2 (Neutrophil Gelatinase-associated Lipocalin/Lipocalin 2) and the N-terminal Domain of Its Endocytic Receptor SLC22A17.
Cabedo Martinez Ana-Isabel, Weinhäupl Katharina, Lee Wing-Kee, Wolff Natascha A, Storch Barbara, Żerko Szymon, Konrat Robert, Koźmiński Wiktor, Breuker Kathrin, Thévenod Frank, Coudevylle Nicolas
N-Lauroylation during the Expression of Recombinant N-Myristoylated Proteins: Implications and Solutions.
Flamm Andrea Gabriele, Le Roux Anabel-Lise, Mateos Borja, Díaz-Lobo Mireia, Storch Barbara, Breuker Kathrin, Konrat Robert, Pons Miquel, Coudevylle Nicolas
Detection of correlated conformational fluctuations in intrinsically disordered proteins through paramagnetic relaxation interference.
Kurzbach D, Vanas A, Flamm A G, Tarnoczi N, Kontaxis G, Maltar-Strmečki N, Widder K, Hinderberger D, Konrat R
IDPs: Less Disordered and More Ordered than Expected.
Konrat Robert
NMR Spectroscopic Studies of the Conformational Ensembles of Intrinsically Disordered Proteins.
Kurzbach Dennis, Kontaxis Georg, Coudevylle Nicolas, Konrat Robert
Novel approaches in selective tryptophan isotope labeling by using Escherichia coli overexpression media.
Schörghuber Julia, Sára Tomáš, Bisaccia Marilena, Schmid Walther, Konrat Robert, Lichtenecker Roman J
(1)H, (15)N, (13)C resonance assignment of human osteopontin.
Platzer Gerald, Żerko Szymon, Saxena Saurabh, Koźmiński Wiktor, Konrat Robert
Magnetic resonance access to transiently formed protein complexes.
Sára Tomáš, Schwarz Thomas C, Kurzbach Dennis, Wunderlich Christoph H, Kreutz Christoph, Konrat Robert