LipA, a tyrosine and lipid phosphatase involved in the virulence of Listeria monocytogenes.
Kastner Renate, Dussurget Olivier, Archambaud Cristel, Kernbauer Elisabeth, Soulat Didier, Cossart Pascale, Decker Thomas
Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling.
Bourgeois Christelle, Majer Olivia, Frohner Ingrid E, Lesiak-Markowicz Iwona, Hildering Kwang-Soo, Glaser Walter, Stockinger Silvia, Decker Thomas, Akira Shizuo, Müller Mathias, Kuchler Karl
Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression.
Farlik Matthias, Reutterer Benjamin, Schindler Christian, Greten Florian, Vogl Claus, Müller Mathias, Decker Thomas
Type I interferons as mediators of immune adjuvants for T- and B cell-dependent acquired immunity.
Prchal Michaela, Pilz Andreas, Simma Olivia, Lingnau Karen, von Gabain Alexander, Strobl Birgit, Müller Mathias, Decker Thomas
Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.
Pilz Andreas, Kratky Wolfgang, Stockinger Silvia, Simma Olivia, Kalinke Ulrich, Lingnau Karen, von Gabain Alexander, Stoiber Dagmar, Sexl Veronika, Kolbe Thomas, Rülicke Thomas, Müller Mathias, Decker Thomas
Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.
Decker Thorsten, Pasca di Magliano Marina, McManus Shane, Sun Qiong, Bonifer Constanze, Tagoh Hiromi, Busslinger Meinrad
Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes.
Stockinger Silvia, Kastner Renate, Kernbauer Elisabeth, Pilz Andreas, Westermayer Sandra, Reutterer Benjamin, Soulat Didier, Stengl Gabriele, Vogl Claus, Frenz Theresa, Waibler Zoe, Taniguchi Tadatsugu, Rülicke Thomas, Kalinke Ulrich, Müller Mathias, Decker Thomas
Identification of an indispensable role for tyrosine kinase 2 in CTL-mediated tumor surveillance.
Simma Olivia, Zebedin Eva, Neugebauer Nina, Schellack Carola, Pilz Andreas, Chang-Rodriguez Souyet, Lingnau Karen, Weisz Eva, Putz Eva Maria, Pickl Winfried F, Felzmann Thomas, Müller Mathias, Decker Thomas, Sexl Veronika, Stoiber Dagmar
The IL-10R1 S138G loss-of-function allele and ulcerative colitis.
Grundtner P, Gruber S, Murray S S, Vermeire S, Rutgeerts P, Decker T, Lakatos P L, Gasche C
Mycobacteria-induced granuloma necrosis depends on IRF-1.
Aly Sahar, Mages Jörg, Reiling Norbert, Kalinke Ulrich, Decker Thomas, Lang Roland, Ehlers Stefan
Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes.
Stockinger Silvia, Decker Thomas
The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response.
Soulat Didier, Bürckstümmer Tilmann, Westermayer Sandra, Goncalves Adriana, Bauch Angela, Stefanovic Adrijana, Hantschel Oliver, Bennett Keiryn L, Decker Thomas, Superti-Furga Giulio
IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages.
Zwaferink Heather, Stockinger Silvia, Hazemi Parastoo, Lemmens-Gruber Rosa, Decker Thomas
Stimulation of inducible nitric oxide synthase expression by beta interferon increases necrotic death of macrophages upon Listeria monocytogenes infection.
Zwaferink Heather, Stockinger Silvia, Reipert Siegfried, Decker Thomas
Type I IFN are host modulators of strain-specific Listeria monocytogenes virulence.
Reutterer Benjamin, Stockinger Silvia, Pilz Andreas, Soulat Didier, Kastner Renate, Westermayer Sandra, Rülicke Thomas, Müller Mathias, Decker Thomas
Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.
Ramsauer Katrin, Farlik Matthias, Zupkovitz Gordin, Seiser Christian, Kröger Andrea, Hauser Hansjörg, Decker Thomas
Negative and positive regulation of gene expression by mouse histone deacetylase 1.
Zupkovitz Gordin, Tischler Julia, Posch Markus, Sadzak Iwona, Ramsauer Katrin, Egger Gerda, Grausenburger Reinhard, Schweifer Norbert, Chiocca Susanna, Decker Thomas, Seiser Christian
Cytoplasmic Listeria monocytogenes stimulates IFN-beta synthesis without requiring the adapter protein MAVS.
Soulat Didier, Bauch Angela, Stockinger Silvia, Superti-Furga Giulio, Decker Thomas
The yin and yang of type I interferon activity in bacterial infection.
Decker Thomas, Müller Mathias, Stockinger Silvia