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Global organelle profiling reveals subcellular localization and remodeling at proteome scale.

2025 Cell;188(4):1137, 1155.e20, 1137-1155.e20.
PMID:  39742809

Hein Marco Y, Peng Duo, Todorova Verina, McCarthy Frank, Kim Kibeom, Liu Chad, Savy Laura, Januel Camille, Baltazar-Nunez Rodrigo, Sekhar Madhurya, Vaid Shivanshi, Bax Sophie, Vangipuram Madhuri, Burgess James, Njoya Leila, Wang Eileen, Ivanov Ivan E, Byrum Janie R, Pradeep Soorya, Gonzalez Carlos G, Aniseia Yttria, Creery Joseph S, McMorrow Aidan H, Sunshine Sara, Yeung-Levy Serena, DeFelice Brian C, Mehta Shalin B, Itzhak Daniel N, Elias Joshua E, Leonetti Manuel D

Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.

2024 The Journal of clinical investigation;134(17)
PMID:  39225101

Winkler Juliane, Tan Weilun, Diadhiou Catherine Mm, McGinnis Christopher S, Abbasi Aamna, Hasnain Saad, Durney Sophia, Atamaniuc Elena, Superville Daphne, Awni Leena, Lee Joyce V, Hinrichs Johanna H, Wagner Patrick S, Singh Namrata, Hein Marco Y, Borja Michael, Detweiler Angela M, Liu Su-Yang, Nanjaraj Ankitha, Sitarama Vaishnavi, Rugo Hope S, Neff Norma, Gartner Zev J, Oliveira Pisco Angela, Goga Andrei, Darmanis Spyros, Werb Zena

Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.

2023 Nature communications;14(1):6245.
PMID:  37803001

Sunshine Sara, Puschnik Andreas S, Replogle Joseph M, Laurie Matthew T, Liu Jamin, Zha Beth Shoshana, Nuñez James K, Byrum Janie R, McMorrow Aidan H, Frieman Matthew B, Winkler Juliane, Qiu Xiaojie, Rosenberg Oren S, Leonetti Manuel D, Ye Chun Jimmie, Weissman Jonathan S, DeRisi Joseph L, Hein Marco Y

OpenCell: Endogenous tagging for the cartography of human cellular organization.

2022 Science (New York, N.Y.)(6585)
PMID:  35271311

Cho Nathan H, Cheveralls Keith C, Brunner Andreas-David, Kim Kibeom, Michaelis André C, Raghavan Preethi, Kobayashi Hirofumi, Savy Laura, Li Jason Y, Canaj Hera, Kim James Y S, Stewart Edna M, Gnann Christian, McCarthy Frank, Cabrera Joana P, Brunetti Rachel M, Chhun Bryant B, Dingle Greg, Hein Marco Y, Huang Bo, Mehta Shalin B, Weissman Jonathan S, Gómez-Sjöberg Rafael, Itzhak Daniel N, Royer Loïc A, Mann Matthias, Leonetti Manuel D

Mapping transcriptomic vector fields of single cells.

2022 Cell(4)
PMID:  35108499

Qiu Xiaojie, Zhang Yan, Martin-Rufino Jorge D, Weng Chen, Hosseinzadeh Shayan, Yang Dian, Pogson Angela N, Hein Marco Y, Hoi Joseph Min Kyung, Wang Li, Grody Emanuelle I, Shurtleff Matthew J, Yuan Ruoshi, Xu Song, Ma Yian, Replogle Joseph M, Lander Eric S, Darmanis Spyros, Bahar Ivet, Sankaran Vijay G, Xing Jianhua, Weissman Jonathan S

Functional single-cell genomics of human cytomegalovirus infection.

2022 Nature biotechnology(3)
PMID:  34697476

Hein Marco Y, Weissman Jonathan S

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