TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration.
Herrera Maria G, Kühn Lena, Jungbluth Lisa, Bader Verian, Krause Laura J, Kartte David, Adriaenssens Elias, Martens Sascha, Tatzelt Jörg, Sachse Carsten, Winklhofer Konstanze F
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy.
Duan Yongjia, Lu Ye, Paul Sanjoy, Betz Johannes, Wilhelm Lea, Cook Annan S I, Ren Xuefeng, Adriaenssens Elias, Martens Sascha, Ganley Ian G, Hummer Gerhard, Hurley James H
Mechanism of autophagy initiation by transmembrane selective autophagy receptors.
Adriaenssens Elias, Martens Sascha
Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery.
Adriaenssens Elias, Schaar Stefan, Cook Annan S I, Stuke Jan F M, Sawa-Makarska Justyna, Nguyen Thanh Ngoc, Ren Xuefeng, Schuschnig Martina, Romanov Julia, Khuu Grace, Uoselis Louise, Lazarou Michael, Hummer Gerhard, Hurley James H, Martens Sascha
The rapidly expanding role of LC3-interacting regions in autophagy.
North Brian J, Fracchiolla Dorotea, Ragusa Michael J, Martens Sascha, Shoemaker Christopher J
Photocatalytic Diselenide Contraction as a Tool for Site-Selective Isosteric Ubiquitylation.
Weissinger Herwig, Urschbach Moritz, Ferrari Luca, Martens Sascha, Becker Christian F W
Convergent Assembly of Homo- and Heterotypic Ubiquitin Chains from Functionalized, Expressed Monomers via Thiol-Ene Chemistry.
Becker Christian F W, Urschbach Moritz, Huhmann Susanne, Appel Dominik, Ferrari Luca, Vogl Dominik, Martens Sascha
Corrigendum to "The Role of ATG9 Vesicles in Autophagosome Biogenesis" [J. Mol. Biol. 436(15) (2024) 168489].
Holzer Elisabeth, Martens Sascha, Tulli Susanna
Recruitment of autophagy initiator TAX1BP1 advances aggrephagy from cargo collection to sequestration.
Bauer Bernd, Idinger Jonas, Schuschnig Martina, Ferrari Luca, Martens Sascha
Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery.
Adriaenssens Elias, Schaar Stefan, Cook Annan S I, Stuke Jan F M, Sawa-Makarska Justyna, Nguyen Thanh Ngoc, Ren Xuefeng, Schuschnig Martina, Romanov Julia, Khuu Grace, Lazarou Michael, Hummer Gerhard, Hurley James H, Martens Sascha
A hitchhiker's guide to autophagy.
Tulli Susanna, Martens Sascha
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD.
Adriaenssens Elias, Nguyen Thanh Ngoc, Sawa-Makarska Justyna, Khuu Grace, Schuschnig Martina, Shoebridge Stephen, Skulsuppaisarn Marvin, Watts Emily Maria, Csalyi Kitti Dora, Padman Benjamin Scott, Lazarou Michael, Martens Sascha
Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion.
Ferrari Luca, Bauer Bernd, Qiu Yue, Schuschnig Martina, Klotz Sigrid, Anrather Dorothea, Juretschke Thomas, Beli Petra, Gelpi Ellen, Martens Sascha
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Offensperger Fabian, Tin Gary, Duran-Frigola Miquel, Hahn Elisa, Dobner Sarah, Ende Christopher W Am, Strohbach Joseph W, Rukavina Andrea, Brennsteiner Vincenth, Ogilvie Kevin, Marella Nara, Kladnik Katharina, Ciuffa Rodolfo, Majmudar Jaimeen D, Field S Denise, Bensimon Ariel, Ferrari Luca, Ferrada Evandro, Ng Amanda, Zhang Zhechun, Degliesposti Gianluca, Boeszoermenyi Andras, Martens Sascha, Stanton Robert, Müller André C, Hannich J Thomas, Hepworth David, Superti-Furga Giulio, Kubicek Stefan, Schenone Monica, Winter Georg E
Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation.
Baumann Verena, Achleitner Sonja, Tulli Susanna, Schuschnig Martina, Klune Lara, Martens Sascha
The Role of ATG9 Vesicles in Autophagosome Biogenesis.
Holzer Elisabeth, Martens Sascha, Tulli Susanna
Sequestration of translation initiation factors in p62 condensates.
Danieli Alberto, Vucak Georg, Baccarini Manuela, Martens Sascha
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling.
Harding Olivia, Holzer Elisabeth, Riley Julia F, Martens Sascha, Holzbaur Erika L F
p62 and NBR1 functions are dispensable for aggrephagy in mouse ESCs and ESC-derived neurons.
Trapannone Riccardo, Romanov Julia, Martens Sascha
The membrane surface as a platform that organizes cellular and biochemical processes.
Leonard Thomas A, Loose Martin, Martens Sascha