Stem cells are capable to differentiate into other more specialised cells, such as neurons in the brain, cells in the digestive tract or cells in our blood system. Not only do they play an important part during development, but they are also found in adult tissue where they help replace lost or damaged cells. Some animals are even able to regrow whole body parts or organs, reflecting the competence of their differentiated cells to revert back to stem cell states.
The FWF funded doctoral candidates will work across a panel of different model systems and deal with fundamental questions of stem cell biology: What mechanisms lead to the formation of a specialised cell from a stem cell? How can animals revert specialised cells to stem cells? And how do stem cells interact to form whole organs?
Students will also receive comprehensive training in the methods of modern stem cell biology, theoretical and conceptual approaches, and bioethical questions. The students will be part of the Vienna BioCenter PhD programme, a highly successful cross-institute doctoral programme.
Dissecting the turgor sensing mechanisms in the blast fungus Magnaporthe oryzae
Pikobodies: What does it take to bioengineer NLR immune receptor-nanobody fusions
scRNA and phylogenetics
Gene regulatory mechanisms governing human development, evolution and variation
Regulation of Cerebral Cortex Morphogenesis by Migrating Cells
Phage therapy for treating bacterial infections: a double-edged sword
Suckers and segments of the octopus arm
Using the house mouse radiation to study the rapid evolution of genes and genetic processes
CRISPR jumps ahead: mechanistic insights into CRISPR-associated transposons
SLiMs and SHelMs: Decoding how short linear and helical motifs direct PPP specificity to direct signaling
Title to be announced
Enigmatic evolutionary origin and multipotency of the neural crest cells - major drivers of vertebrate evolution
Visualising mitotic chromosomes and nuclear dynamics by correlative light and electron microscopy
Engineered nanocarriers for imaging of small proteins by CryoEM
Bacterial cell envelope homeostasis at the (post)transcriptional level
Title to be announced
Hydrologic extremes alter mechanisms and pathways of carbon export from mountainous floodplain soils
Dissecting post-transcriptional gene expression regulation in humans and viruses
Polyploidy and rediploidisation in stressful times
Prdm9 control of meiotic synapsis of homologs in intersubspecific hybrids
Title to be announced
RNA virus from museum specimens
Programmed DNA double-strand breaks during meiosis: Mechanism and evolution
Title to be announced