Key Discovery

CRISPR/Cas 9 - how gene scissors work

Investigation of the mechanism of the CRISPR/Cas9 bacterial defense system has revolutionized biology, triggering applications in gene editing for basic and applied research in every organism imaginable. The basis for the revolutionary application of the CRISPR-Cas9 system was developed by Emmanuelle Charpentier at the Max Perutz Labs.

The widely acclaimed CRISPR-Cas9 genome engineering technology exploits a defense system naturally found in many bacteria. To protect themselves against foreign genetic elements such as those present in invading viruses and plasmids, bacteria incorporate short pieces of foreign DNA into segments of their own genomes that are called CRISPR (clustered regularly interspaced short palindromic repeats). These CRISPR regions thus provide a ‘memory’ of invading elements that can be used by a bacterial population to defend themselves more effectively when subsequently challenged by a similar invader. The CRISPR segments containing invader sequences are expressed as CRISPR RNAs (crRNAs) that match foreign DNA. crRNAs in duplex with a second RNA molecule, tracrRNA, binds to DNA and hence help to recruit a specific enzyme (Cas9) that can then specifically dismantle the invading DNA.

Key steps of this intriguingly simple molecular defense mechanism were elucidated at the University of Vienna at the Max Perutz Labs at the Vienna BioCenter by Emmanuelle Charpentier and her group also at the Laboratory for Molecular Infection Medicine Sweden, Umeå University. In a first landmark publication with the master’s student Elitza Deltcheva as lead author (Deltcheva et al., Nature 2011), the team serendipitously discovered the so-called tracrRNA that forms duplexes with the repeats of long precursor forms of crRNAs and thus activates the process that cleaves the long pre-crRNAs into individual sequences able to guide Cas9 to its targets. In 2012, the team subsequently published (in conjunction with their collaborators from Jennifer Doudna’s group at Berkeley) a breakthrough study (Jinek, Chylinski et al., Science 2012) that revealed the exact molecular mechanism of the type II CRISPR-Cas9 system. Crucially, this study also demonstrated that the mechanism could be engineered into a simple, two-component system (a duplex of tracrRNA-crRNA or a single guide RNA plus the Cas9 enzyme) that can easily be “programmed” by scientists to bind and cleave any DNA sequence of interest. This two-component system (commonly referred to as CRISPR-Cas9) has quickly become enormously popular, and triggered an avalanche of applications, most notably in the site-specific editing of genomes. Due to its simplicity, the system has meanwhile been used for genome editing in numerous species, greatly expanding the biomedical toolbox.

The pivotal role of former MFPL group leader Emmanuelle Charpentier and her team has been recognized globally. Charpentier has been awarded a series of scientific prizes and other recognitions, including the 2015 Breakthrough Prize, which recognizes transformative advances towards understanding living systems and extending human life, and the 2018 Kavli Prize, recognizing scientists for their seminal advances in astrophysics, nanoscience, or neuroscience. Krzysztof Chylinski, the Vienna BioCenter PhD student who was second author on the 2011 study, and shared first author on the 2012 publication, continued his work on CRISPR-Cas9 at the Vienna BioCenter Core Facilities (VBCF) until 2020. He has received the Vienna BioCenter PhD award, the Bank Austria Research Award, and the Award of Excellence from the Austrian Federal government for his critical contributions. The CRISPR-Cas9 system and its manifold variations hold enormous promise for the understanding and treatment of conditions ranging from cancer and ageing to inherited genetic disorders, as well as having a huge range of potential applications in agriculture. It may even be used to eliminate the mosquito that transmits malaria. 

The discovery of the tracrRNA and the development of the bacterial CRISPR-Cas9 system as a powerful genetic engineering technology at the Max Perutz Labs wonderfully illustrate the role of serendipity in basic research and support the adage of physicist Joseph John Thomson that “research in pure science leads to revolutions”. 

 

Original Publications in Nature and Science:

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.

Read more

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Read more

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18
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25
Sep 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: KOK Jian Yi (Berger), HUMER Theresa (Pauli), SODERHOLM Adrian (Versteeg)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
28
Sep 2023
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Stephan GruberInstitute: University of LausanneHost: Franz Klein

Mon
02
Oct 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: STRAVS Ana (Knoblich), SANCHEZ DE MEDINA HERNANDEZ Victor (Dagdas), KRUMWIEDE Luisa (Gaidt)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
09
Oct 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: TAVERINI Katherina (Urban), SHETTY Kavya Krishna (Stark), CORIC Aida (Tessmar)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
12
Oct 2023
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Nancy KlecknerInstitute: Harvard UniversityHost: Franz Klein

Mon
16
Oct 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: GRABARCZYK Daniel (Clausen), PROTELL I DE MONTSERRAT Julia (Brennecke/Plaschka), MANCHENO JUNCOSA Estela (Mendjan)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
19
Oct 2023
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Edward LemkeInstitute: IMB MainzHost: David Haselbach

Mon
23
Oct 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: ATTRILL Sarah (Dolan), UIJTTEWAAL Esther (Elling), SCIBISZ Grzegorz (Karagöz)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
30
Oct 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: DOLESCHALL Balint (Knoblich), FENG Sonjie (Bücker), BOURGUET Pierre (Berger)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
02
Nov 2023
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Rotem SorekInstitute: Weizmann Institute of Science, RehovotHost: Julius Brennecke

Mon
06
Nov 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: HORENKAMP Simone (Tanaka), CASEY Chloe (Dolan), KAPRAL Thomas (Zagrovic)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
13
Nov 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: KOBAKHIDZE George (Dong), ANGELOPOULOU Eleni (Ellis), PACHANO Tomas (Stark)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
20
Nov 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: RAMIREZ America (Köhler), VÖLKL Isabella (Bücker), HOANG Oi Pui (Technau)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
23
Nov 2023
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Mounia LaghaInstitute: Institut de Genetique Moleculaire de MontpellierHost: Andrea Pauli

Mon
27
Nov 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: LEITNER Moritz (Martinez), VOGEL Alexander (Yudushkin), KETTEL Paulina (Karagöz)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
04
Dec 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: TSAREV Aleksandr (Ameres), FIESELER Charlie (Zimmer), ABESAMIS Kim Ivan (Dong)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
11
Dec 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: STREUBEL Susanna (Dolan), KLEIFELD Justus (Urban), ORLIC Lucija (Matos)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
18
Dec 2023
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: SHULKINA Alexandra (Versteeg), GEETHA Sowmya (Jantsch), MADHUSUDHANAN Jalaja (Zimmer)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
08
Jan 2024
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: KOLLER Manuela (Campbell), GUPTA Ankit (Goloborodko), SCHMÖLLERL Johannes (Zuber)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
15
Jan 2024
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: MARCHIORI Elisa (Van der Veeken), ACHLEITNER Anja (Martens), FAAS Victoria (Clausen)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
22
Jan 2024
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: SALEWSKIJ Kirill (Penninger), KIRCHGATTERER Paul (Gaidt), REN Kaike (Otsuka)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
29
Jan 2024
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: MIHAILOVIC Milica (Karagöz), BELL Lillie (Clausen)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

  • Name
    Phone
    Mail
    Function
    Group
    Room
  • A
  • Kim Ivan Abesamis
    +43-1-4277-61626
    PhD Student
    Dong
    3.127
    Main Building
  • Elisabeth Ableitner
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Sonja Achleitner
    +43-1-4277-54632
    PhD Student
    Martens
    5.401
    Main Building
  • Leonie Adelmann
    +43-1-4277-54616
    PhD Student
    Raible
    4.115
    Main Building
  • Marlene Adlhart
    +43-1-4277-52272
    Technician
    Zagrovic
    1.114
    VBC 5
  • Elias Adriaenssens
    +43-1-4277-52828
    PostDoc
    Martens
    5.401
    Main Building
  • Vasilina Akulova
    +43-1-4277-74320
    PhD Student
    Swarts
    1.722.1
    VBC 5
  • Mustafa Alaabo
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Sadia Sabrina Alam
    +43-1-4277-52810
    Bachmair
    5.108/5.109
    Main Building
  • Tanino Albanese
    +43-1-4277-54632
    PhD Student
    4.129
    Main Building
  • Santiago Alonso Gil
    +43-1-4277-52272
    PostDoc
    Zagrovic
    1.114
    VBC 5
  • Manuel Alonso Y Adell
    +43-1-4277-52808
    PostDoc
    Campbell
    5.512/5.513
    Main Building
  • Kerstin Altenburger
    +43-1-4277-54631
    Diploma/Master Student
    Bläsi
    4.122/4.124
    Main Building
  • Thomas Altmutter
    +43-1-4277-24003
    Administration
    3.117
    Main Building
  • Stefan Ameres
    +43-1-4277-54693
    Group Leader
    Ameres
    2.119
    Main Building
  • Gabriele Andreatta
    +43-1-4277-74636
    PostDoc
    Tessmar
    4.501
    Main Building
  • Eleni Angelopoulou
    +43-1-4277-74649
    PhD Student
    Ellis
    3.121
    Main Building
  • Aleksandra Anisimova
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • Dorothea Anrather
    +43-1-4277-52846
    Senior Proteomics Specialist
    E72
  • Sumire Antonioli
    +43-1-4277-52241
    PhD Student
    Leonard
    1.222
    VBC 5
  • Lisa Appel
    +43-1-4277-52807
    PhD Student
    Slade
    5.508
    Main Building
  • Alexis Arizpe
    +43-1-79044-9942
    PhD Student
    Swarts
    1104
    VBC 5
  • Hossein Arzani
    +43-1-4277-61812
    PhD Student
    Kuchler
    2.107
    Main Building
  • Igor Asanovic
    +43-1-4277-61815
    PhD Student
    Martinez
    2.512
    Main Building
  • Gerlinde Aschauer
    +43-1-4277-52851
    Program manager
    5.119
    Main Building
  • Zahra Ayatollahi
    +43-1-4277-61609
    Administration
    Martens
    3.518
    Main Building
  • Daniel Aziz
    +43-1-4277-74320
    Diploma/Master Student
    Juffmann
    1.722
    VBC 5
  • B
  • Olga Babadei
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Julia Babel
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Manuela Baccarini
    +43-1-4277-54607
    Group Leader
    Baccarini
    4.628
    Main Building
  • Andreas Bachmair
    +43-1-4277-74811
    Group Leader
    Bachmair
    5.110
    Main Building
  • Gergely Bakocai
    +43-1-4277-61785
    Lab Assistant
    2.527
    Main Building
  • Elizabeta Banic Ochsenhofer
    +43-1-4277-54621
    PostDoc
    Dammermann
    4.508
    Main Building
  • Matthias Bärnthaler
    +43-1-4277-24041
    Head of IT
    4.420
    Main Building
  • Andrea Barta
    +43-1-4277-61640
    Lecturer
    Barta
    3.520
    Main Building
  • Antoine Baudrimont
    +43-1-4277-56261
    PostDoc
    Jantsch V
    5.522
    Main Building
  • Bernd Bauer
    +43-1-4277-24001
    PhD Student
    Martens
    5.503
    Main Building
  • Verena Baumann
    +43-1-4277-52838
    PostDoc
    Martens
    5.401
    Main Building
  • Clara Beer
    +43-1-4277-74601
    Diploma/Master Student
    Witte
    4.125/4.127
    Main Building
  • Nikolaus Beer
    +43-1-4277-52801
    Diploma/Master Student
    Ameres
    2.125
    Main Building
  • Andreas Beier
    +43-1-4277-52227
    PhD Student
    Konrat
    0614
    VBC 5
  • Helen Belalcazar
    +43-1-4277-61628
    PostDoc
    Köhler A
    3.527
    Main Building
  • Andrej Belokurov
    +43-1-4277-24080
    Facility Technician
    Tessmar
    0.413
    Main Building
  • Johannes Benedum
    +43-1-4277-52807
    PhD Student
    Slade
    5.508
    Main Building
  • Maximilian Benesch
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Christian Bernhart
    +43-1-4277-52812
    IT Support
    5.617
    Main Building
  • Daniel Bernklau
    +43-1-4277-52828
    PhD Student
    Martens
    5.502
    Main Building
  • Patrick Berthold
    +43-1-4277-24072
    Facility Manager
    1.117
    Main Building
  • Annika Bestehorn
    +43-1-4277-54626
    PhD Student
    Kovarik
    4.514
    Main Building
  • Michael Bindl
    +43-1-4277-61645
    PhD Student
    Leeb
    3.123/3.125
    Main Building
  • Head of Biooptics Facility
    +43-1-4277-61672
    PostDoc
    1.618
    VBC 5
  • Nora Bischoff
    +43-1-4277-54625
    Technician
    Kovarik
    4.514
    Main Building
  • Dieter Blaas
    +43-1-4277-61630
    Lecturer
    Blaas
    3.520
    Main Building
  • Udo Bläsi
    +43-1-4277-54609
    Group Leader
    Bläsi
    4.121
    Main Building
  • Sonja Bleichert
    +43-1-4277-74649
    Technician
    Ellis
    3.121
    Main Building
  • Laura Boccuni
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Margaryta Borysova
    +43-1-4277-24080
    Facility Manager
    Raible
    0.413
    Main Building
  • Helena Bragulat Teixidor
    +43-1-4277-61668
    PhD Student
    Otsuka
    3.505
    Main Building
  • Daniel Braun
    +43-1-4277-52227
    PostDoc
    Konrat
    0614
    VBC 5
  • Barbara Brumec
    +43-1-4277-61661
    Technician
    3.518
    Main Building
  • Stefania Bucconi
    +43-1-4277-74645
    Technician
    Leeb
    3.123/3.125
    Main Building
  • Chloé Bucheron
    +43-1-4277-74371
    Diploma/Master Student
    Menche
    1.104
    Main Building
  • Valentina Budroni
    +43-1-4277-54164
    PhD Student
    Versteeg
    4.108
    Main Building
  • Christa Buecker
    +43-1-4277-74646
    Group Leader
    Bücker
    3.626
    Main Building
  • Anna Burger
    +43-1-4277-24061
    Facility Technician
    8.318
    Main Building
  • Sebastian Burgstaller-Muehlbacher
    +43-1-4277-74324
    PostDoc
    v. Haeseler
    1.812.4
    VBC 5
  • Virginia Busetto
    +43-1-4277-74320
    PostDoc
    Falk
    1.624
    VBC 5
  • C
  • Christopher Campbell
    +43-1-4277-52808
    Group Leader
    Campbell
    5.610
    Main Building
  • Oliviero Carugo
    +43-1-4277-52208
    Djinovic
    1.120
    VBC 5
  • Irene Ceccolini
    +43-1-4277-52229
    PhD Student
    Konrat
    0614
    VBC 5
  • Chiara Ceriotti
    +43-1-79730-3450
    5.10
    IMP/IMBA
  • Luis Miguel Cerron Alvan
    +43-1-4277-74645
    PhD Student
    Leeb
    3.123/3.125
    Main Building
  • Weiqiang Chen
    +43-1-4277-52846
    Proteomics Specialist
    E72
  • Doris Chen
    +43-1-4277-74328
    PostDoc
    Klein
    1.812.3
    VBC 5
  • Martin Chiettini
    +43-1-4277-74390
    Technician
    Menche
    1803
    VBC 5
  • Marius Constantin Chirita Mihaila
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.614
    VBC 5
  • Anastasia Cianciulli Sesso
    +43-1-4277-54631
    PhD Student
    Bläsi
    4.122/4.124
    Main Building
  • Natasa Cirovic
    +43-1-4277-74320
    v. Haeseler
    1.812.1
    VBC 5
  • Clara Conrad-Billroth
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.614
    VBC 5
  • Aida Coric
    +43-1-4277-74636
    PhD Student
    Tessmar
    4.501
    Main Building
  • Renate Coufal
    +43-1-4277-24071
    Facility Manager
    1.117
    Main Building
  • Kitti Dora Csalyi
    +43-1-4277-24051
    Facility Head
    2.530
    Main Building
  • Andrea Czerny
    +43-1-4277-61606
    Lab Assistant
    3.515
    Main Building
  • D
  • Alexander Dammermann
    +43-1-4277-54681
    Group Leader
    Dammermann
    4.609
    Main Building
  • Alberto Danieli
    +43-1-4277-52805
    PhD Student
    Martens
    5.503
    Main Building
  • Thomas Decker
    +43-1-4277-54605
    Group Leader
    Decker
    4.112
    Main Building
  • Isabel Del Pino Gomez
    +43-1-4277-54601
    Lab Assistant
    4.211/4.411
    Main Building
  • Sebastian Didusch
    +43-1-4277-54629
    PhD Student
    Baccarini
    4.525/4.527
    Main Building
  • Margarita Dillinger
    +43-1-4277-54621
    Technician
    Dammermann
    4.508
    Main Building
  • Ines Dittrich
    +43-1-4277-56241
    Technician
    5.524/5.526
    Main Building
  • Kristina Djinovic-Carugo
    +43-1-4277-52203
    Group Leader
    Djinovic
    1.606
    VBC 5
  • Jeroen Dobbelaere
    +43-1-4277-54619
    PostDoc
    Dammermann
    4.510/4.512
    Main Building
  • Gang Dong
    +43-1-4277-61625
    Group Leader
    Dong
    3.501
    Main Building
  • Anežka Dostálová
    +43-1-4277-72520
    Juffmann
    1.211
    VBC 5
  • Corinne Drexler
    +43-1-4277-52866
    PhD Student
    Fuchs
    5.506
    Main Building
  • Sharif Duale
    +43-1-4277-61785
    Technician
    2.527
    Main Building
  • Monika Ducka
    +43-1-4277-74825
    Technician
    Ameres
    2.126
    Main Building
  • E
  • Karin Ehrenreiter
    +43-1-4277-54617
    Administration
    Baccarini
    4.114
    Main Building
  • Michael Eigenschink
    +43-1-4277-61669
    Müllner
    2.524
    Main Building
  • David Eisele
    +43-1-4277-52272
    Diploma/Master Student
    Zagrovic
    1.114
    VBC 5
  • Christiane Elgert
    +43-1-4277-74325
    PostDoc
    v. Haeseler
    1.812.4
    VBC 5
  • Stephanie Ellis
    +43-1-4277-74648
    Group Leader
    Ellis
    3.118
    Main Building
  • Magdalena Engl
    +43-1-4277-52807
    PhD Student
    Slade
    5.508
    Main Building
  • Rainer Ettelt
    +43-1-4277-54630
    PhD Student
    Baccarini
    4.529
    Main Building
  • F
  • Martin Fahrenberger
    +43-1-4277-74330
    PhD Student
    v. Haeseler
    1.812.2
    VBC 5
  • Sebastian Falk
    +43-1-4277-74360
    Group Leader
    Falk
    1.620
    VBC 5
  • Anna Falkner
    +43-1-4277-52807
    Technician
    Slade
    5.508
    Main Building
  • Michel Fasnacht
    +43-1-4277-54632
    PostDoc
    Moll
    4.129
    Main Building
  • Renate Fauland
    +43-1-4277-50115
    Administration
    6.111a
    Main Building
  • Songjie Feng
    +43-1-4277-74647
    PhD Student
    Bücker
    3.510/3.512
    Main Building
  • Luca Ferrari
    +43-1-4277-52828
    PostDoc
    Martens
    5.502
    Main Building
  • Jeanne Fesselet
    +43-1-4277-54626
    PhD Student
    Kovarik
    4.516
    Main Building
  • Daria Filipczak
    +43-1-4277-61681
    PhD Student
    Foisner
    3.110
    Main Building
  • Patrick Fischer
    +43-1-4277-52807
    Slade
    5.610
    Main Building
  • Philipp Fischer
    +43-1-4277-54628
    Technician
    Kovarik
    4.525/4.527
    Main Building
  • Katrin Fischer
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Sabine Fischer
    +43-1-4277-24014
    Administration
    3.117
    Main Building
  • Irmgard Fischer
    +43-1-4277-52866
    Imaging Specialist (In House Microscopes)
    5.401
    Main Building
  • Roland Foisner
    +43-1-4277-61680
    Group Leader
    Foisner
    3.113
    Main Building
  • Maurizio Forte
    +43-1-4277-54626
    PhD Student
    Kovarik
    4.516
    Main Building
  • Elisabeth Friesinger
    +43-1-4277-74647
    Diploma/Master Student
    Bücker
    3.513
    Main Building
  • Magdalena Fritz
    +43-1-4277-61707
    Müllner
    2.530
    Main Building
  • Ingrid Frohner
    +43-1-4277-61740
    PostDoc
    Ogris
    2.130
    Main Building
  • Peter Fuchs
    +43-1-4277-52855
    Group Leader
    Fuchs
    5.024
    Main Building
  • Sándor Fülöp
    +43-1-4277-24013
    Administration
    3.117
    Main Building
  • G
  • Laura Gallego
    +43-1-4277-61641
    PostDoc
    Köhler A
    3.522
    Main Building
  • Philipp Galuska
    +43-1-4277-52263
    PhD Student
    Djinovic
    0114
    VBC 5
  • Julia Garcia Baucells
    +43-1-4277-24001
    PhD Student
    Dammermann
    4.508
    Main Building
  • David Gaßner
    +43-1-4277-61626
    Diploma/Master Student
    Dong
    3.127
    Main Building
  • Kirsten Gassner
    +43-1-4277-54643
    Diploma/Master Student
    Witte
    4.128
    Main Building
  • Konstantina Georgiou
    +43-1-4277-61681
    PhD Student
    Foisner
    3.110
    Main Building
  • Devon Germain
    +43-1-4277-61823
    PostDoc
    Martinez
    2.515
    Main Building
  • Tanja Gesell
    +43-1-4277-52292
    1.610
    VBC 5
  • Netsanet Getachew
    +43-1-4277-74636
    Technician
    Raible
    4.501
    Main Building
  • Enrico Ghezzi
    +43-1-4277-24001
    Administration
    6.112A
    Main Building
  • Sara Gionco
    +43-1-4277-0000
    Diploma/Master Student
    Martens
    5.401
    Main Building
  • Julia Gobl
    +43-1-4277-52275
    Leonard
    1.321.1
    VBC 5
  • Anastasiia Gorbenkova
    +43-1-4277-61815
    Diploma/Master Student
    Martinez
    2.515
    Main Building
  • Boris Görke
    +43-1-4277-54603
    Group Leader
    Görke
    4.113
    Main Building
  • Irene Gösler
    +43-1-4277-61673
    Lab Manager
    Foisner
    3.108
    Main Building
  • Josef Gotzmann
    +43-1-4277-61672
    Head of Facility
    1.618
    VBC 5
  • Angela Graf
    +43-1-4277-56261
    Technician
    Jantsch V
    5.522
    Main Building
  • Claudia Graf
    +43-1-4277-24012
    Administration
    6.109
    Main Building
  • Lucas Grandits
    +43-1-4277-72523
    Diploma/Master Student
    Juffmann
    1.614
    VBC 5
  • Christa Gregori-Schüller
    +43-1-4277-61806
    PostDoc
    Kuchler
    2.111
    Main Building
  • Katarzyna Gruber
    +43-1-4277-24075
    Lab Assistant
    1.117
    Main Building
  • Iris Gruber
    +43-1-4277-74320
    Administration
    v. Haeseler
    1.604
    VBC 5
  • Juliane Gruber
    +43-1-4277-52811
    Diploma/Master Student
    Slade
    5.610
    Main Building
  • Attila György
    +43-1-4277-24065
    Technician
    3.501
    Main Building
  • H
  • Katharina Haberler
    +43-1-4277-56201
    Administration
    5.115
    Main Building
  • Kathrin Hacker
    +43-1-4277-74638
    Technician
    Versteeg
    4.108
    Main Building
  • Thomas Haden
    +43-1-4277-24042
    IT Support
    2.116
    Main Building
  • Leila Hadziabdic
    +43-1-4277-54632
    PhD Student
    Moll
    4.129
    Main Building
  • Simon Haendeler
    +43-1-4277-74329
    PhD Student
    v. Haeseler
    1.812.2
    VBC 5
  • Sören Häfker
    +43-1-4277-74641
    PostDoc
    Tessmar
    4.504/4.506
    Main Building
  • Anna Hakobyan
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Barbara Hamilton
    +43-1-4277-52814
    Administration
    6.111a
    Main Building
  • Joel Hancock
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Robert Happel
    +43-1-4277-74322
    IT Support
    v. Haeseler
    1.812.1
    VBC 5
  • Andreas Hartig
    +43-1-4277- 52817
    Lecturer
    Hartig
    5.110
    Main Building
  • Natascha Hartl
    +43-1-4277-52846
    Senior Technician
    E72
  • Markus Hartl
    +43-1-4277-52846
    Head of Facility
    5.10
    IMP/IMBA
  • Felix Hartmann
    +43-1-4277-52862
    PhD Student
    Matos
    5.125/5.127
    Main Building
  • Lisa Haselbach
    +43-1-4277-61801
    Administration
    2.115
    Main Building
  • Felix Haslhofer
    +43-1-4277--
    Diploma/Master Student
    Tessmar
    4.501
    Main Building
  • Marco Hein
    +43-1-4277-61701
    Hein
    2.115
    Main Building
  • Adrian Henggeler
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Joachim Hermisson
    +43-1-4277-74351
    Group Leader
    Hermisson
    1.722.1
    VBC 5
  • Felix Hitzelhammer
    +43-1-4277-52213
    Diploma/Master Student
    Juffmann
    1.722
    VBC 5
  • Reinhold Hofbauer
    +43-1-4277-61750
    Lecturer
    Hofbauer
    2.519
    Main Building
  • Juergen Hoffmann
    +43-1-4277-52213
    Technician
    1.620
    VBC 5
  • Franziska Hofstetter
    +43-1-4277-61761
    Diploma/Master Student
    Weitzer
    2.522
    Main Building
  • Theresa Höfurthner
    +43-1-4277-52263
    PhD Student
    Konrat
    0114
    VBC 5
  • Laurenz Holcik
    +43-1-4277-74325
    PhD Student
    v. Haeseler
    1.812.3
    VBC 5
  • Elisabeth Holzer
    +43-1-4277-52828
    PhD Student
    Martens
    5.502
    Main Building
  • Julian Holzinger
    +43-1-4277-52229
    PostDoc
    Konrat
    0614
    VBC 5
  • Harald Hornegger
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • Marie Huber
    +43-1-4277-74647
    Technician
    Bücker
    3.510/3.512
    Main Building
  • Theresa Hügel
    +43-1-4277-74640
    Program manager
    Baccarini
    4.116
    Main Building
  • Michelle Huth
    +43-1-4277-74645
    PhD Student
    Leeb
    3.123/3.125
    Main Building
  • Christiane Hütter
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • I
  • Kyojiro Ikeda
    +43-1-4277-74636
    PostDoc
    Raible
    4.501
    Main Building
  • Natale-Erwin Ivessa
    +43-1-4277-61805
    Lecturer
    Ivessa
    2.118
    Main Building
  • J
  • Hanieh Jafarian
    +43-1-4277-72524
    PhD Student
    Juffmann
    1.722
    VBC 5
  • Verena Jantsch-Plunger
    +43-1-4277-56250
    Group Leader
    Jantsch V
    5.118
    Main Building
  • Nele Jarnot
    +43-1-4277-72523
    Diploma/Master Student
    Juffmann
    1.614
    VBC 5
  • Swathi Jayaram
    +43-1-4277-74646
    PhD Student
    Bücker
    3.510/3.512
    Main Building
  • Christina Jones
    +43-1-4277-3.123
    Diploma/Master Student
    Leeb
    3.123/3.125
    Main Building
  • Isha Joshi
    +43-1-4277-56240
    PhD Student
    Schlögelhofer
    5.524/5.526
    Main Building
  • Aleksandra Jovanovic
    +43-1-4277-52806
    Lab Manager
    Ammerer
    2.122
    Main Building
  • Thomas Juffmann
    +43-1-4277-72520
    Group Leader
    Juffmann
    1.610
    VBC 5
  • Jose Julian Valenzuela
    +43-1-4277-52810
    PostDoc
    Bachmair
    5.108/5.109
    Main Building
  • Elisabeth Jursa
    +43-1-4277-52875
    Lab Assistant
    5.325
    Main Building
  • K
  • Lisa Kainz
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Manfred Kaiser
    +43-1-4277-74328
    Diploma/Master Student
    v. Haeseler
    1.812.3
    VBC 5
  • Lakshmi Kalathinkunnath
    +43-1-4277-74636
    PhD Student
    Tessmar
    4.501
    Main Building
  • Petra-Franziska Kalman
    +43-1-4277-61831
    Lab Manager
    Martinez
    2.522
    Main Building
  • Thomas Kapral
    +43-1-4277-52272
    PhD Student
    Zagrovic
    1.114
    VBC 5
  • Arda Kara
    +43-1-4277-61626
    Diploma/Master Student
    Dong
    3.127
    Main Building
  • Elif Karagöz
    +43-1-4277-61635
    Group Leader
    Karagöz
    3.507/ 3.508
    Main Building
  • Nataliia Kashko
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Ruben Kastner
    +43-1-4277-56241
    Apprentice
    Schlögelhofer
    5.524/5.526
    Main Building
  • Clemens Kauffmann
    +43-1-4277-52229
    PostDoc
    Konrat
    0614
    VBC 5
  • Helga Kaufmann
    +43-1-4277-52801
    Lab Assistant
    5.210/5.410
    Main Building
  • Manpreet Kaur
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.722
    VBC 5
  • Paulina Kettel
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • Nina Khaldieh
    +43-1-4277-52801
    PhD Student
    Ameres
    2.122
    Main Building
  • AMEYA RAKESH KHANDEKAR
    +43-1-4277-61823
    PhD Student
    Martinez
    2.512
    Main Building
  • Uladzislava Khauratovich
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Sami Khawam
    +43-1-4277-74320
    PostDoc
    Juffmann
    1.610
    VBC 5
  • Narakorn Khunweeraphong
    +43-1-4277-61818
    PostDoc
    Kuchler
    2.509
    Main Building
  • Franz Klein
    +43-1-4277-56220
    Group Leader
    Klein
    5.114
    Main Building
  • Tamara Klockner
    +43-1-4277-52808
    PhD Student
    Campbell
    5.512/5.513
    Main Building
  • Lara Klune
    +43-1-4277-52828
    Diploma/Master Student
    Martens
    5.503
    Main Building
  • George Kobakhidze
    +43-1-4277-61626
    PhD Student
    Dong
    3.127
    Main Building
  • Julia Kober
    +43-1-4277-61761
    Diploma/Master Student
    Weitzer
    2.522
    Main Building
  • Anna Koch
    +43-1-4277-52814
    Diploma/Master Student
    Witte
    4.125/4.127
    Main Building
  • Anne Barbara Koehle
    +43-1-4277-56261
    Diploma/Master Student
    Jantsch V
    5.522
    Main Building
  • Katharina Kogler
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Alwin Köhler
    +43-1-4277-61685
    Group Leader
    Köhler A
    3.626
    Main Building
  • Claudia Kölbl
    +43-1-4277-56261
    Diploma/Master Student
    Jantsch V
    5.522
    Main Building
  • Manuela Sophie Koller
    +43-1-4277-53808
    PhD Student
    Campbell
    5.512/5.513
    Main Building
  • Benjamin Koltschik
    +43-1-4277-4125
    Diploma/Master Student
    Witte
    4.128
    Main Building
  • Dhaarsini Koneswarakantha
    +43-1-4277-61821
    PostDoc
    Martinez
    2.515
    Main Building
  • Werner König
    +43-1-4277-52210
    Technician
    1.608
    VBC 5
  • Robert Konrat
    +43-1-4277-52202
    Group Leader
    Konrat
    1.602
    VBC 5
  • Georg Kontaxis
    +43-1-4277-52218
    Facility Manager
    1.608
    VBC 5
  • Katharina Korbula
    +43-1-4277-61626
    Lab Manager
    Dong
    3.127
    Main Building
  • Pavel Kovarik
    +43-1-4277-54608
    Group Leader
    Kovarik
    4.615
    Main Building
  • Saskia Kowald
    +43-1-4277-74644
    Diploma/Master Student
    Leeb
    3.123/3.125
    Main Building
  • Heinrich Kowalski
    +43-1-4277-61612
    Group Leader
    Kowalski
    3.026
    Main Building
  • Fiona Krammer
    +43-1-4277-74645
    Diploma/Master Student
    Leeb
    3.123/3.125
    Main Building
  • Kevin Alexander Kranz
    +43-1-4277-74361
    Diploma/Master Student
    Falk
    1.624
    VBC 5
  • Nesrete Krasnici
    +43-1-4277-52236
    Technician
    Djinovic
    0326
    VBC 5
  • Karl Kuchler
    +43-1-4277-61807
    Group Leader
    Kuchler
    2.111
    Main Building
  • Julius Kühn
    +43-1-4277-54629
    Diploma/Master Student
    Baccarini
    4.525/4.527
    Main Building
  • Chanchal Kumawat
    +43-1-4277-52225
    PostDoc
    Djinovic
    0612
    VBC 5
  • Claudia Kuntner
    +43-1-4277-56221
    Diploma/Master Student
    Klein
    5.528/5.530
    Main Building
  • Patricia-Emanuela Kutin
    +43-1-4277-61606
    Lab Assistant
    3.515
    Main Building
  • L
  • Josef Laurin
    +43-1-4277-54626
    Diploma/Master Student
    Kovarik
    4.514
    Main Building
  • Karin Ledolter
    +43-1-4277-52260
    Lab Manager
    Konrat
    0122
    VBC 5
  • Martin Leeb
    +43-1-4277-74644
    Group Leader
    Leeb
    3.123/3.125
    Main Building
  • Günther Leitgeb
    +43-1-4277-54633
    IT Management
    4.420
    Main Building
  • Moritz Leitner
    +43-1-4277-61816
    PhD Student
    Martinez
    2.512
    Main Building
  • Thomas Lenert
    +43-1-4277-61602
    Administration
    3.115
    Main Building
  • Thomas Leonard
    +43-1-4277-52205
    Group Leader
    Leonard
    1.616
    VBC 5
  • Alina Leuchtenberger
    +43-1-4277-74330
    PhD Student
    v. Haeseler
    1.812.2
    VBC 5
  • Aleksandra Levina
    +43-1-4277-52275
    PhD Student
    Leonard
    1.321
    VBC 5
  • Wei Chiang Liao
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Raffael Lichtenberger
    +43-1-4277-61656
    Lab Manager
    Falk
    1.624
    VBC 5
  • Branislav Lilic
    +43-1-4277-54631
    PhD Student
    Bläsi
    4.122/4.124
    Main Building
  • Sarah Linauer
    +43-1-4277-61704
    Technician
    Ogris
    2.127
    Main Building
  • Josef Loidl
    +43-1-4277-56210
    Group Leader
    Loidl
    5.515
    Main Building
  • Salvo Danilo Lombardo
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • M
  • Moritz Madern
    +43-1-79044-4291
    E72
  • Dante Maestre
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.722
    VBC 5
  • Daniel Malzl
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Christina Manakanatas
    +43-1-4277-74644
    PhD Student
    Foisner
    3.123/3.125
    Main Building
  • Toni Manolova
    +43-1-4277-61656
    PhD Student
    Falk
    1.624
    VBC 5
  • Raphaël Marchand
    +43-1-4277-72523
    PostDoc
    Juffmann
    1.614
    VBC 5
  • Ana Markovic
    +43-1-4277-52808
    Diploma/Master Student
    Campbell
    5.610
    Main Building
  • Laura Marosits
    +43-1-4277-61635
    Technician
    Karagöz
    3.507/ 3.508
    Main Building
  • Theodor Marsoner
    +43-1-4277-52808
    PhD Student
    Campbell
    5.512/5.513
    Main Building
  • Sascha Martens
    +43-1-4277-52876
    Group Leader
    Martens
    5.113
    Main Building
  • Javier Martinez
    +43-1-4277-61803
    Group Leader
    Martinez
    2.113
    Main Building
  • Fabien Martins
    +43-1-4277-24010
    Financial Director
    6.107
    Main Building
  • Angela Martins
    +43-1-4277-54601
    Administration
    4.114
    Main Building
  • Iryna Martsun
    +43-1-4277-47310
    Diploma/Master Student
    Tessmar
    0.413
    Main Building
  • Audrey Mat
    +43-1-4277-54618
    PostDoc
    Tessmar
    4.510/4.512
    Main Building
  • Joao Matos
    +43-1-4277-74419
    Group Leader
    Matos
    5.024
    Main Building
  • Theresa Matzinger
    +43-1-4277-61761
    Technician
    Weitzer
    2.522
    Main Building
  • Rounik Mazumdar
    +43-1-4277-61818
    PostDoc
    Kuchler
    2.505
    Main Building
  • Jörg Menche
    +43-1-4277-74370
    Group Leader
    Menche
    1804
    VBC 5
  • Mario Migotti
    +43-1-4277-52263
    PhD Student
    Konrat
    0114
    VBC 5
  • Milica Mihailovic
    +43-1-4277-61635
    PhD Student
    Karagöz
    3.502
    Main Building
  • Nadja Milivojev
    +43-1-4277-74636
    PhD Student
    Raible
    4.510/4.512
    Main Building
  • Frane Miljkovic
    +43-1-4277-61643
    PhD Student
    Köhler A
    3.524
    Main Building
  • Olja Milojevic
    +43-1-4277-74610
    Diploma/Master Student
    Görke
    4.110
    Main Building
  • Isabella Moll
    +43-1-4277-54606
    Group Leader
    Moll
    4.028
    Main Building
  • Giasemi Angeliki Moraitou
    +43-1-4277-56241
    Diploma/Master Student
    Schlögelhofer
    5.524/5.526
    Main Building
  • Ingrid Mudrak
    +43-1-4277-61740
    Lab Manager
    Ogris
    2.030
    Main Building
  • Amra Mujadzic
    +43-1-4277-52810
    Bachmair
    5.108/5.109
    Main Building
  • Felix Müller
    +43-1-4277-74371
    Senior PostDoc
    Menche
    1104
    VBC 5
  • Fränze Müller
    +43-1-4277-4282
    PostDoc
    Jantsch V
    5.623
    Main Building
  • Ernst Müllner
    +43-1-4277-61783
    Group Leader
    Müllner
    2.523
    Main Building
  • Melitta Münster
    +43-1-4277-52275
    Lab Manager
    Zagrovic
    1.321
    VBC 5
  • Adnan Muratovic
    +43-1-4277-61653
    Diploma/Master Student
    Karagöz
    3.507/ 3.508
    Main Building
  • N
  • Julia Naas
    +43-1-4277-74328
    PhD Student
    v. Haeseler
    1.812.3
    VBC 5
  • Nana Naetar-Kerenyi
    +43-1-4277-61671
    PostDoc
    Foisner
    3.108
    Main Building
  • Valentina Nakic
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Tsimafei Navalayeu
    +43-1-4277-52801
    PhD Student
    Ameres
    2.125
    Main Building
  • Lilian Nehlin
    +43-1-4277-52810
    PostDoc
    Bachmair
    5.108/5.109
    Main Building
  • Melissa Neumann
    +43-1-4277-24072
    Facility Staff
    0.116
    Main Building
  • Yap Shing Nim
    +43-1-4277-61649
    PostDoc
    Köhler A
    3.527
    Main Building
  • Johannes Nimpf
    +43-1-4277-61808
    Group Leader
    Nimpf
    2.112
    Main Building
  • Adrian Nogales Moral
    +43-1-4277-61643
    PhD Student
    Köhler A
    3.524
    Main Building
  • O
  • Michael Oberhuemer
    +43-1-4277-74645
    PhD Student
    Leeb
    3.123/3.125
    Main Building
  • Till Pascal Oblau
    +43-1-4277-74371
    Diploma/Master Student
    Menche
    1.104
    Main Building
  • Egon Ogris
    +43-1-4277-61730
    Group Leader
    Ogris
    2.117
    Main Building
  • Julia Okrina
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Anastasia Okun
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • Lukas Orel
    +43-1-4277-74636
    Lab Manager
    Tessmar
    4.501
    Main Building
  • Lucija Orlić
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Shotaro Otsuka
    +43-1-4277-61665
    Group Leader
    Otsuka
    3.506
    Main Building
  • Ö
  • Sidar Özer
    +43-1-4277-24042
    IT Support
    2.116
    Main Building
  • O
  • Pedro Ozorio Brum
    +43-1-4277-54616
    PhD Student
    Tessmar
    4.504/4.506
    Main Building
  • P
  • Claudia Pachinger
    +43-1-4277-54621
    PhD Student
    Dammermann
    4.508
    Main Building
  • Michele Paganini
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Nathan Palmer
    +43-1-4277-56231
    PostDoc
    Matos
    5.122/5.123
    Main Building
  • Katarzyna Paniak
    +43-1-4277-74649
    Diploma/Master Student
    Ellis
    3.121
    Main Building
  • Dimitra Paouneskou
    +43-1-4277-56261
    PostDoc
    Jantsch V
    5.522
    Main Building
  • Paulina Parafiniuk-Borzecki
    +43-1-4277-52801
    Administration
    5.115
    Main Building
  • Rajvi Shashi Patel
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Anzhela Pavlova
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Julia Pazmandi
    +43-1-4277-74372
    PostDoc
    Menche
    1104
    VBC 5
  • Philipp Penninger
    +43-1-4277-61812
    PhD Student
    Kuchler
    2.107
    Main Building
  • Cassius Manuel Perez de los Cobos Hermosa
    +43-1-4277-74326
    PhD Student
    v. Haeseler
    1.812.5
    VBC 5
  • Lara Veronika Perko Budja
    +43-1-4277-74610
    Diploma/Master Student
    Görke
    4.110
    Main Building
  • Thomas Peterbauer
    +43-1-4277-61676
    Senior Imaging Specialist
    1.618
    VBC 5
  • Jan Petržílek
    +43-1-4277-52801
    PhD Student
    Ameres
    2.122
    Main Building
  • Vasiliki Petroulaki
    +43-1-4277-56231
    PhD Student
    Matos
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    1803
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    0612
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