Key Discovery

CRISPR/Cas 9 - how gene scissors work

Investigation of the mechanism of the CRISPR/Cas9 bacterial defense system has revolutionized biology, triggering applications in gene editing for basic and applied research in every organism imaginable. The basis for the revolutionary application of the CRISPR-Cas9 system was developed by Emmanuelle Charpentier at the Max Perutz Labs.

The widely acclaimed CRISPR-Cas9 genome engineering technology exploits a defense system naturally found in many bacteria. To protect themselves against foreign genetic elements such as those present in invading viruses and plasmids, bacteria incorporate short pieces of foreign DNA into segments of their own genomes that are called CRISPR (clustered regularly interspaced short palindromic repeats). These CRISPR regions thus provide a ‘memory’ of invading elements that can be used by a bacterial population to defend themselves more effectively when subsequently challenged by a similar invader. The CRISPR segments containing invader sequences are expressed as CRISPR RNAs (crRNAs) that match foreign DNA. crRNAs in duplex with a second RNA molecule, tracrRNA, binds to DNA and hence help to recruit a specific enzyme (Cas9) that can then specifically dismantle the invading DNA.

Key steps of this intriguingly simple molecular defense mechanism were elucidated at the University of Vienna at the Max Perutz Labs at the Vienna BioCenter by Emmanuelle Charpentier and her group also at the Laboratory for Molecular Infection Medicine Sweden, Umeå University. In a first landmark publication with the master’s student Elitza Deltcheva as lead author (Deltcheva et al., Nature 2011), the team serendipitously discovered the so-called tracrRNA that forms duplexes with the repeats of long precursor forms of crRNAs and thus activates the process that cleaves the long pre-crRNAs into individual sequences able to guide Cas9 to its targets. In 2012, the team subsequently published (in conjunction with their collaborators from Jennifer Doudna’s group at Berkeley) a breakthrough study (Jinek, Chylinski et al., Science 2012) that revealed the exact molecular mechanism of the type II CRISPR-Cas9 system. Crucially, this study also demonstrated that the mechanism could be engineered into a simple, two-component system (a duplex of tracrRNA-crRNA or a single guide RNA plus the Cas9 enzyme) that can easily be “programmed” by scientists to bind and cleave any DNA sequence of interest. This two-component system (commonly referred to as CRISPR-Cas9) has quickly become enormously popular, and triggered an avalanche of applications, most notably in the site-specific editing of genomes. Due to its simplicity, the system has meanwhile been used for genome editing in numerous species, greatly expanding the biomedical toolbox.

The pivotal role of former MFPL group leader Emmanuelle Charpentier and her team has been recognized globally. Charpentier has been awarded a series of scientific prizes and other recognitions, including the 2015 Breakthrough Prize, which recognizes transformative advances towards understanding living systems and extending human life, and the 2018 Kavli Prize, recognizing scientists for their seminal advances in astrophysics, nanoscience, or neuroscience. Krzysztof Chylinski, the Vienna BioCenter PhD student who was second author on the 2011 study, and shared first author on the 2012 publication, continued his work on CRISPR-Cas9 at the Vienna BioCenter Core Facilities (VBCF) until 2020. He has received the Vienna BioCenter PhD award, the Bank Austria Research Award, and the Award of Excellence from the Austrian Federal government for his critical contributions. The CRISPR-Cas9 system and its manifold variations hold enormous promise for the understanding and treatment of conditions ranging from cancer and ageing to inherited genetic disorders, as well as having a huge range of potential applications in agriculture. It may even be used to eliminate the mosquito that transmits malaria. 

The discovery of the tracrRNA and the development of the bacterial CRISPR-Cas9 system as a powerful genetic engineering technology at the Max Perutz Labs wonderfully illustrate the role of serendipity in basic research and support the adage of physicist Joseph John Thomson that “research in pure science leads to revolutions”. 

 

Original Publications in Nature and Science:

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III.

Read more

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Read more

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29
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12
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19
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22
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Speaker: Benoit BruneauInstitute: Gladstone InstitutesHost: Sasha Mendjan

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26
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28
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29
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03
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Mon
10
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17
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Thu
20
Oct 2022
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Long CaiInstitute: CaltechHost: Daniel Gerlich

Mon
24
Oct 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: LIU Haijun (Nordborg), NAVALAYE Tsimafei (Ameres), NAAS Julia (Von Haeseler)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
31
Oct 2022
Monday Seminar

Monday Seminar (Internal)
  12:00 - 13:00
  IMP Lecture Hall

Speaker: CHUGUNOVA Anastasia (Pauli), RÖTZER Johannes (Dolan), JONSSON Gustav (Penninger)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
07
Nov 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: KLAUS Loni (Stark), GROH Roan (Djinovic-Carugo), LITTLEBOY Jamie (Knoblich)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
10
Nov 2022
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Daniel MucidaInstitute: Rockefeller UniversityHost: Meinrad Busslinger

Mon
14
Nov 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: ANTONIOLI Sumire (Leonard), LI Chong (Knoblich), PABST Gabriel (Zuber)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
17
Nov 2022
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Lacra BintuInstitute: Stanford UniversityHost: Alex Stark

Mon
21
Nov 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: DIEZMA Laura (Nordborg/Mari-Ordonez), GHOSH Dipannita (Grade), PATEL Rajvi (Matos)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Sun
27
Nov 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: KORDIC Darja (Clausen), DEIBER Sebastian (Dolan), GEHRE Maja (Brennecke)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Thu
01
Dec 2022
VBC Regular Seminar

Title to be announced
  11:00 - 12:00
  IMBA/GMI Lecture Hall

Speaker: Hans CleversInstitute: Hubrecht InstituteHost: Jürgen Knoblich

Mon
05
Dec 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: ZMAJKOVIC Jakub (Zuber), MAURER Eric (Peters), NOGALES MORAL Adrian (Köhler)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
12
Dec 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: HUETTER Christiane (Menche), BASSAT Elad (Tanaka), PETRZILEK Jan (Ameres)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

Mon
19
Dec 2022
Monday Seminar

Monday Seminar (Internal)
  12:30 - 13:30
  IMP Lecture Hall

Speaker: KALIS Robert (Zuber), NAJM Ramsey (Knoblich), GEROCZ Emoke (Gerlich)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs

  • Name
    Phone
    Mail
    Function
    Group
    Room
  • A
  • Omer Rashid Abdi
    +43-1-4277-61643
    Apprentice
    Köhler A
    3.524
    Main Building
  • Elisabeth Ableitner
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Sonja Achleitner
    +43-1-4277-54632
    Diploma/Master Student
    Martens
    5.401
    Main Building
  • Elias Adriaenssens
    +43-1-4277-52828
    PostDoc
    Martens
    5.401
    Main Building
  • Vasilina Akulova
    +43-1-4277-74320
    PhD Student
    Swarts
    1.722.1
    VBC 5
  • Mariam Al-Rawi
    +43-1-4277-74040
    Technician Vienna COVID-19 Detection Initiative
    Köhler A
    4622
    VBC 5
  • Mustafa Alaabo
    +43-1-4277-74646
    Diploma/Master Student
    Bücker
    3.510/3.512
    Main Building
  • Tanino Albanese
    +43-1-4277-54632
    Technician Vienna COVID-19 Detection Initiative
    Köhler A
    4.129
    Main Building
  • Santiago Alonso Gil
    +43-1-4277-52272
    PostDoc
    Zagrovic
    1.114
    VBC 5
  • Manuel Alonso Y Adell
    +43-1-4277-52808
    PostDoc
    Campbell
    5.512/5.513
    Main Building
  • Thomas Altmutter
    +43-1-4277-24003
    IT Support
    3.117
    Main Building
  • Stefan Ameres
    +43-1-4277-54693
    Group Leader
    Ameres
    2.119
    Main Building
  • Gabriele Andreatta
    +43-1-4277-74636
    PostDoc
    Raible
    4.501
    Main Building
  • Aleksandra Anisimova
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • Dorothea Anrather
    +43-1-4277-52846
    Senior PostDoc
    E72
  • Sumire Antonioli
    +43-1-4277-52241
    PhD Student
    Leonard
    1.222
    VBC 5
  • Lisa Appel
    +43-1-4277-52807
    PhD Student
    Slade
    5.508
    Main Building
  • Alexis Arizpe
    +43-1-79044-9942
    PhD Student
    Swarts
    1104
    VBC 5
  • Hossein Arzani
    +43-1-4277-61812
    PhD Student
    Kuchler
    2.107
    Main Building
  • Igor Asanovic
    +43-1-4277-61815
    PhD Student
    Martinez
    2.512
    Main Building
  • Gerlinde Aschauer
    +43-1-4277-52851
    Program manager
    5.119
    Main Building
  • Mila Asparuhova
    +43-1-4277-61635
    Technician
    Karagöz
    3.507/ 3.508
    Main Building
  • Zahra Ayatollahi
    +43-1-4277-61609
    PostDoc
    Barta
    3.518
    Main Building
  • B
  • Olga Babadei
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Manuela Baccarini
    +43-1-4277-54607
    Group Leader
    Baccarini
    4.628
    Main Building
  • Andreas Bachmair
    +43-1-4277-74811
    Group Leader
    Bachmair
    5.110
    Main Building
  • Gergely Bakocai
    +43-1-4277-61785
    Lab Assistant
    2.527
    Main Building
  • Ralph Baldrian
    +43-1-4277-54631
    Diploma/Master Student
    Bläsi
    4.121
    Main Building
  • Elizabeta Banic
    +43-1-4277-54621
    PostDoc
    Dammermann
    4.508
    Main Building
  • Matthias Bärnthaler
    +43-1-4277-24041
    Head of IT
    4.420
    Main Building
  • Andrea Barta
    +43-1-4277-61640
    Lecturer
    Barta
    3.520
    Main Building
  • Antoine Baudrimont
    +43-1-4277-56261
    PostDoc
    Jantsch V
    5.522
    Main Building
  • Bernd Bauer
    +43-1-4277-24001
    PhD Student
    Martens
    5.503
    Main Building
  • Verena Baumann
    +43-1-4277-52838
    PhD Student
    Martens
    5.401
    Main Building
  • Mirjam Beck
    +43-1-4277-61609
    Program manager
    Martens
    3.518
    Main Building
  • Nikolaus Beer
    +43-1-4277-52801
    Diploma/Master Student
    Ameres
    2.125
    Main Building
  • Andreas Beier
    +43-1-4277-52227
    PhD Student
    Konrat
    0614
    VBC 5
  • Andrej Belokurov
    +43-1-4277-24080
    Facility Technician
    Tessmar
    0.413
    Main Building
  • Johannes Benedum
    +43-1-4277-52807
    PhD Student
    Slade
    5.508
    Main Building
  • Maximilian Benesch
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Christian Bernhart
    +43-1-4277-52812
    IT Support
    5.617
    Main Building
  • Daniel Bernklau
    +43-1-4277-52828
    PhD Student
    Martens
    5.502
    Main Building
  • Patrick Berthold
    +43-1-4277-24072
    Facility Staff
    1.117
    Main Building
  • Annika Bestehorn
    +43-1-4277-54626
    PhD Student
    Kovarik
    4.514
    Main Building
  • Meret Beyer
    +43-1-4277-52263
    Diploma/Master Student
    Djinovic
    0.114
    Main Building
  • Angela Bienert
    +43-1-4277-61811
    Administration
    Kuchler
    2.107
    Main Building
  • Ivana Bilusic
    +43-1-4277-52804
    PhD Student
    Schroeder
    5.502
    Main Building
  • Wolfgang Binder
    +43-1-4277-24060
    Technician
    3.501
    Main Building
  • Michael Bindl
    +43-1-4277-61645
    Diploma/Master Student
    Leeb
    3.123/3.125
    Main Building
  • Head of Biooptics Facility
    +43-1-4277-61672
    PostDoc
    1.618
    VBC 5
  • Nora Bischoff
    +43-1-4277-54625
    Technician
    Kovarik
    4.514
    Main Building
  • Dieter Blaas
    +43-1-4277-61630
    Group Leader
    Blaas
    3.026
    Main Building
  • Udo Bläsi
    +43-1-4277-54609
    Group Leader
    Bläsi
    4.121
    Main Building
  • Laura Boccuni
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Jörg Böckelmann
    +43-1-4277-52206
    Administration
    Djinovic
    1.604
    VBC 5
  • Margaryta Borysova
    +43-1-4277-24080
    Technician
    0.413
    Main Building
  • Veronika Boskova
    +43-1-4277-74330
    PostDoc
    v. Haeseler
    1.812.3
    VBC 5
  • Helena Bragulat Teixidor
    +43-1-4277-61668
    PhD Student
    Otsuka
    3.505
    Main Building
  • Stefanie Brandstetter
    +43-1-4277-74320
    Diploma/Master Student
    Zagrovic
    1.114
    VBC 5
  • Daniel Braun
    +43-1-4277-52272
    PostDoc
    Zagrovic
    1.114
    VBC 5
  • Barbara Brumec
    +43-1-4277-61661
    Technician
    3.518
    Main Building
  • Valentina Budroni
    +43-1-4277-54164
    PhD Student
    Versteeg
    4.108
    Main Building
  • Christa Buecker
    +43-1-4277-74646
    Group Leader
    Bücker
    3.626
    Main Building
  • Pisanu Buphamalai
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Anna Burger
    +43-1-4277-24061
    Facility Technician
    8.318
    Main Building
  • Sebastian Burgstaller-Muehlbacher
    +43-1-4277-74324
    PostDoc
    v. Haeseler
    1.812.4
    VBC 5
  • Virginia Busetto
    +43-1-4277-74320
    PostDoc
    Falk
    1.624
    VBC 5
  • C
  • Christopher Campbell
    +43-1-4277-52808
    Group Leader
    Campbell
    5.610
    Main Building
  • Oliviero Carugo
    +43-1-4277-52208
    Djinovic
    1.120
    VBC 5
  • Irene Ceccolini
    +43-1-4277-52229
    PhD Student
    Konrat
    0614
    VBC 5
  • Chiara Ceriotti
    +43-1-79730-3450
    5.10
    IMP/IMBA
  • Luis Miguel Cerron Alvan
    +43-1-4277-74645
    PhD Student
    Leeb
    3.123/3.125
    Main Building
  • Ms. Chanchal
    +43-1-4277-52225
    PostDoc
    Djinovic
    1.612
    VBC 5
  • Weiqiang Chen
    +43-1-4277-52846
    Senior PostDoc
    E72
  • Doris Chen
    +43-1-4277-74328
    PostDoc
    Klein
    1.812.3
    VBC 5
  • Olga Chernomor
    +43-1-4277-74325
    PostDoc
    v. Haeseler
    1.812.4
    VBC 5
  • Martin Chiettini
    +43-1-4277-74390
    Technician
    Menche
    1803
    VBC 5
  • Marius Constantin Chirita Mihaila
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.614
    VBC 5
  • Anastasia Cianciulli Sesso
    +43-1-4277-54631
    PhD Student
    Bläsi
    4.122/4.124
    Main Building
  • Agata Cieśla
    +43-1-4277-52810
    Bachmair
    5.108/5.109
    Main Building
  • Natasa Cirovic
    +43-1-4277-74320
    v. Haeseler
    1.812.1
    VBC 5
  • Clara Conrad-Billroth
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.614
    VBC 5
  • Aida Coric
    +43-1-4277-74636
    PhD Student
    Tessmar
    4.501
    Main Building
  • Nicolas Coudevylle
    +43-1-4277-52838
    PostDoc
    Martens
    5.401
    Main Building
  • Renate Coufal
    +43-1-4277-24071
    Facility Staff
    1.117
    Main Building
  • Kitti Dora Csalyi
    +43-1-4277-24051
    PostDoc
    2.530
    Main Building
  • Andrea Czerny
    +43-1-4277-61606
    Lab Assistant
    3.515
    Main Building
  • D
  • Alexander Dammermann
    +43-1-4277-54681
    Group Leader
    Dammermann
    4.609
    Main Building
  • Alberto Danieli
    +43-1-4277-52805
    PhD Student
    Martens
    5.503
    Main Building
  • Pauline Dao
    +43-1-4277-54618
    PhD Student
    Tessmar
    4.510/4.512
    Main Building
  • Thomas Decker
    +43-1-4277-54605
    Group Leader
    Decker
    4.112
    Main Building
  • Isabel Del Pino Gomez
    +43-1-4277-54601
    Lab Assistant
    4.211/4.411
    Main Building
  • Maria Rosaria Dello Stritto
    +43-1-4277-56261
    PostDoc
    Jantsch V
    5.522
    Main Building
  • Sebastian Didusch
    +43-1-4277-54629
    PhD Student
    Baccarini
    4.525/4.527
    Main Building
  • Ines Dittrich
    +43-1-4277-56241
    Technician
    5.524/5.526
    Main Building
  • Kaan Dizer
    +43-1-4277-24001
    Campbell
    5.512/5.513
    Main Building
  • Kristina Djinovic-Carugo
    +43-1-4277-52203
    Group Leader
    Djinovic
    1.606
    VBC 5
  • Paula Dlugosz
    +43-1-4277-61809
    PostDoc
    Nimpf
    2.110
    Main Building
  • Jeroen Dobbelaere
    +43-1-4277-54619
    PostDoc
    Dammermann
    4.510/4.512
    Main Building
  • Gang Dong
    +43-1-4277-61625
    Group Leader
    Dong
    3.501
    Main Building
  • Corinne Drexler
    +43-1-4277-52866
    PhD Student
    Fuchs
    5.506
    Main Building
  • Sharif Duale
    +43-1-4277-61785
    Technician
    2.527
    Main Building
  • Monika Ducka
    +43-1-4277-74825
    Technician
    Ameres
    2.126
    Main Building
  • E
  • Mirijam Egg
    +43-1-4277-74646
    Diploma/Master Student
    Bücker
    3.510/3.512
    Main Building
  • Martin Egyed
    +43-1-4277-61656
    Diploma/Master Student
    Falk
    1.624
    VBC 5
  • Karin Ehrenreiter
    +43-1-4277-54617
    Administration
    Baccarini
    4.114
    Main Building
  • Michael Eigenschink
    +43-1-4277-61669
    Müllner
    2.524
    Main Building
  • Janina Eislmayr
    +43-1-4277-54626
    Diploma/Master Student
    Kovarik
    4.516
    Main Building
  • Kevin Eislmayr
    +43-1-4277-54626
    PostDoc
    Kovarik
    4.516
    Main Building
  • Aybala Eker
    +43-1-4277-61812
    Lab Assistant
    Kuchler
    2.107
    Main Building
  • Christiane Elgert
    +43-1-4277-74325
    PostDoc
    v. Haeseler
    1.812.4
    VBC 5
  • Stephanie Ellis
    Group Leader
    Ellis
    3.213
    Main Building
  • Magdalena Engl
    +43-1-4277-52807
    PhD Student
    Slade
    5.508
    Main Building
  • Rainer Ettelt
    +43-1-4277-54630
    PhD Student
    Baccarini
    4.529
    Main Building
  • F
  • Martin Fahrenberger
    +43-1-4277-74330
    PhD Student
    v. Haeseler
    1.812.2
    VBC 5
  • Sebastian Falk
    +43-1-4277-74360
    Group Leader
    Falk
    1.622.1
    VBC 5
  • Renate Fauland
    +43-1-4277-50115
    Administration
    6.111a
    Main Building
  • Michael Feichtinger
    +43-1-4277-52227
    PhD Student
    Konrat
    0614
    VBC 5
  • Songjie Feng
    +43-1-4277-74647
    PhD Student
    Bücker
    3.510/3.512
    Main Building
  • Andrè Ferdigg
    +43-1-4277-61815
    Martinez
    2.512
    Main Building
  • Luca Ferrari
    +43-1-4277-52828
    PostDoc
    Martens
    5.502
    Main Building
  • Inês Ferreira Coelho
    +43-1-4277-74320
    PhD Student
    v. Haeseler
    1.812.3
    VBC 5
  • Jeanne Fesselet
    +43-1-4277-54626
    PhD Student
    Kovarik
    4.516
    Main Building
  • Petra Fichtinger
    +43-1-4277-61681
    Lab Manager
    Foisner
    3.110
    Main Building
  • Eddye Javier Figueroa Marquez
    +43-1-4277-52206
    Diploma/Master Student
    Djinovic
    0612
    VBC 5
  • Daria Filipczak
    +43-1-4277-61681
    PhD Student
    Foisner
    3.110
    Main Building
  • Philipp Fischer
    +43-1-4277-54628
    Technician
    Kovarik
    4.525/4.527
    Main Building
  • Katrin Fischer
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Sabine Fischer
    +43-1-4277-24014
    Administration
    3.117
    Main Building
  • Irmgard Fischer
    +43-1-4277-52866
    Imaging Specialist (In House Microscopes)
    5.401
    Main Building
  • Roland Foisner
    +43-1-4277-61680
    Group Leader
    Foisner
    3.113
    Main Building
  • Dominic Földvári
    +43-1-4277-74320
    PhD Student
    v. Haeseler
    1.812.3
    VBC 5
  • Maurizio Forte
    +43-1-4277-54626
    PhD Student
    Kovarik
    4.516
    Main Building
  • Dorotea Fracchiolla
    +43-1-4277-52805
    PostDoc
    Martens
    5.502
    Main Building
  • Ingrid Frohner
    +43-1-4277-61740
    PostDoc
    Ogris
    2.130
    Main Building
  • Peter Fuchs
    +43-1-4277-52855
    Group Leader
    Fuchs
    5.024
    Main Building
  • Sándor Fülöp
    +43-1-4277-24013
    Administration
    3.117
    Main Building
  • G
  • Laura Gallego
    +43-1-4277-61641
    PostDoc
    Köhler A
    3.522
    Main Building
  • Julia Garcia Baucells
    +43-1-4277-24001
    PhD Student
    Dammermann
    4.508
    Main Building
  • Konstantina Georgiou
    +43-1-4277-61681
    PhD Student
    Foisner
    3.110
    Main Building
  • Devon Germain
    +43-1-4277-61823
    PostDoc
    Martinez
    2.515
    Main Building
  • Tanja Gesell
    +43-1-4277-52292
    1.610
    VBC 5
  • Netsanet Getachew
    +43-1-4277-74636
    Technician
    Tessmar
    4.501
    Main Building
  • Enrico Ghezzi
    +43-1-4277-24001
    6.112A
    Main Building
  • Sarah Gimenes
    +43-1-4277-52236
    Technician
    Djinovic
    0326
    VBC 5
  • Natasa Goncin
    +43-1-4277-74636
    Diploma/Master Student
    Tessmar
    4.501
    Main Building
  • Anastasiia Gorbenkova
    +43-1-4277-61815
    Martinez
    2.515
    Main Building
  • Boris Görke
    +43-1-4277-54603
    Group Leader
    Görke
    4.113
    Main Building
  • Irene Gösler
    +43-1-4277-61632
    Lab Manager
    Blaas
    3.129
    Main Building
  • Josef Gotzmann
    +43-1-4277-61672
    Head of Facility
    1.618
    VBC 5
  • Angela Graf
    +43-1-4277-56261
    Technician
    Jantsch V
    5.522
    Main Building
  • Claudia Graf
    +43-1-4277-24012
    Administration
    6.109
    Main Building
  • Lucas Grandits
    +43-1-4277-72523
    Diploma/Master Student
    Juffmann
    1.614
    VBC 5
  • Christa Gregori-Schüller
    +43-1-4277-61806
    PostDoc
    Kuchler
    2.111
    Main Building
  • Rokas Grigaitis
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Tamara Groffics
    +43-1-4277-61668
    Lab Manager
    Otsuka
    3.505
    Main Building
  • Roan René Groh
    +43-1-4277-52225
    PhD Student
    Djinovic
    0612
    VBC 5
  • Katarzyna Gruber
    +43-1-4277-24075
    Lab Assistant
    1.117
    Main Building
  • Iris Gruber
    +43-1-4277-74320
    Administration
    v. Haeseler
    1.604
    VBC 5
  • Stephan Grüner
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Ricardo Mauricio Gudino Carrillo
    +43-1-4277-61641
    Technician
    Köhler A
    3.522
    Main Building
  • Attila György
    +43-1-4277-24065
    Technician
    3.501
    Main Building
  • H
  • Katharina Haberler
    +43-1-4277-56201
    Administration
    5.115
    Main Building
  • Kathrin Hacker
    +43-1-4277-74638
    Technician
    Versteeg
    4.108
    Main Building
  • Thomas Haden
    +43-1-4277-24042
    IT Support
    2.116
    Main Building
  • Simon Haendeler
    +43-1-4277-74329
    PhD Student
    v. Haeseler
    1.812.2
    VBC 5
  • Sören Häfker
    +43-1-4277-74641
    PostDoc
    Tessmar
    4.504/4.506
    Main Building
  • Anna Hakobyan
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Barbara Hamilton
    +43-1-4277-52814
    Administration
    6.111a
    Main Building
  • Joel Hancock
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Robert Happel
    +43-1-4277-74322
    IT Support
    v. Haeseler
    1.812.1
    VBC 5
  • Andreas Hartig
    +43-1-4277- 52817
    Lecturer
    Hartig
    5.110
    Main Building
  • Natascha Hartl
    +43-1-4277-52846
    Technician
    E72
  • Markus Hartl
    +43-1-4277-52846
    Head of Facility
    5.10
    IMP/IMBA
  • Lisa Haselbach
    +43-1-4277-61801
    Administration
    2.115
    Main Building
  • Adrian Henggeler
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Joachim Hermisson
    +43-1-4277-74351
    Group Leader
    Hermisson
    1.722.1
    VBC 5
  • Felix Hitzelhammer
    +43-1-4277-52213
    Juffmann
    1.722
    VBC 5
  • Reinhold Hofbauer
    +43-1-4277-61750
    Lecturer
    Hofbauer
    2.519
    Main Building
  • Juergen Hoffmann
    +43-1-4277-52213
    Technician
    1.620
    VBC 5
  • Franziska Hofstetter
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Theresa Höfurthner
    +43-1-4277-52263
    PhD Student
    Konrat
    0114
    VBC 5
  • Laurenz Holcik
    +43-1-4277-74325
    PhD Student
    v. Haeseler
    1.812.3
    VBC 5
  • Elisabeth Holzer
    +43-1-4277-54681
    Diploma/Master Student
    Dammermann
    4.510/4.512
    Main Building
  • Julian Holzinger
    +43-1-4277-52219
    PostDoc
    Konrat
    1.608
    VBC 5
  • Harald Hornegger
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • Lingzhi Huang
    +43-1-4277-56221
    PostDoc
    Klein
    5.401
    Main Building
  • Marie Huber
    +43-1-4277-74647
    Technician
    Bücker
    3.510/3.512
    Main Building
  • Theresa Hügel
    +43-1-4277-74640
    Program manager
    Baccarini
    4.116
    Main Building
  • Anna Hurt
    +43-1-4277-54618
    Diploma/Master Student
    Tessmar
    4.501
    Main Building
  • Christiane Hütter
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • I
  • Lydia Ioannidi
    +43-1-4277-56231
    Technician
    Matos
    5.122/5.123
    Main Building
  • Johanna Irnstorfer
    +43-1-4277-61823
    Diploma/Master Student
    Martinez
    2.512
    Main Building
  • Natale-Erwin Ivessa
    +43-1-4277-61805
    Lecturer
    Ivessa
    2.118
    Main Building
  • J
  • Hanieh Jafarian
    +43-1-4277-72524
    PhD Student
    Juffmann
    1.722
    VBC 5
  • Verena Jantsch-Plunger
    +43-1-4277-56250
    Group Leader
    Jantsch V
    5.118
    Main Building
  • Swathi Jayaram
    +43-1-4277-74646
    PhD Student
    Bücker
    3.510/3.512
    Main Building
  • Aleksandra Jovanovic
    +43-1-4277-52806
    Lab Manager
    Ammerer
    2.122
    Main Building
  • Thomas Juffmann
    +43-1-4277-72520
    Group Leader
    Juffmann
    1.610
    VBC 5
  • Jose Julian Valenzuela
    +43-1-4277-52810
    PostDoc
    Bachmair
    5.108/5.109
    Main Building
  • Elisabeth Jursa
    +43-1-4277-52875
    Lab Assistant
    5.325
    Main Building
  • K
  • Lisa Kainz
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Lakshmi Kalathinkunnath
    +43-1-4277-74636
    PhD Student
    Tessmar
    4.501
    Main Building
  • Petra-Franziska Kalman
    +43-1-4277-61831
    Lab Manager
    Martinez
    2.522
    Main Building
  • Thomas Kapral
    +43-1-4277-52272
    Technician
    Zagrovic
    1.114
    VBC 5
  • Arda Kara
    +43-1-4277-61626
    Dong
    3.502
    Main Building
  • Elif Karagöz
    +43-1-4277-61635
    Group Leader
    Karagöz
    3.507/ 3.508
    Main Building
  • Clemens Kauffmann
    +43-1-4277-52292
    PhD Student
    Konrat
    0614
    VBC 5
  • Helga Kaufmann
    +43-1-4277-52801
    Lab Assistant
    5.210/5.410
    Main Building
  • Manpreet Kaur
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.722
    VBC 5
  • Paulina Kettel
    +43-1-4277-61653
    PhD Student
    Karagöz
    3.507/ 3.508
    Main Building
  • AMEYA RAKESH KHANDEKAR
    +43-1-4277-61823
    PhD Student
    Martinez
    2.512
    Main Building
  • Uladzislava Khauratovich
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Sami Khawam
    +43-1-4277-74320
    PostDoc
    Juffmann
    1.610
    VBC 5
  • Narakorn Khunweeraphong
    +43-1-4277-61818
    PostDoc
    Kuchler
    2.509
    Main Building
  • Egor Kiselev
    +43-1-4277-74328
    PostDoc
    v. Haeseler
    1.812.3
    VBC 5
  • Franz Klein
    +43-1-4277-56220
    Group Leader
    Klein
    5.114
    Main Building
  • Tamara Klockner
    +43-1-4277-52808
    PhD Student
    Campbell
    5.512/5.513
    Main Building
  • Anna Koch
    +43-1-4277-52814
    Diploma/Master Student
    Witte
    4.125/4.127
    Main Building
  • Alwin Köhler
    +43-1-4277-61685
    Group Leader
    Köhler A
    3.626
    Main Building
  • Manuela Sophie Koller
    +43-1-4277-53808
    PhD Student
    Campbell
    5.512/5.513
    Main Building
  • Dhaarsini Koneswarakantha
    +43-1-4277-61821
    PhD Student
    Martinez
    2.515
    Main Building
  • Werner König
    +43-1-4277-52210
    Technician
    1.620
    VBC 5
  • Robert Konrat
    +43-1-4277-52202
    Group Leader
    Konrat
    1.602
    VBC 5
  • Georg Kontaxis
    +43-1-4277-52218
    Facility Manager
    1.608
    VBC 5
  • Katharina Korbula
    +43-1-4277-61626
    Lab Manager
    Dong
    3.501
    Main Building
  • Julius Kostan
    +43-1-4277-52263
    Senior PostDoc
    Djinovic
    0114
    VBC 5
  • Pavel Kovarik
    +43-1-4277-54608
    Group Leader
    Kovarik
    4.615
    Main Building
  • Heinrich Kowalski
    +43-1-4277-61612
    Group Leader
    Kowalski
    3.026
    Main Building
  • Aida Kozlic
    +43-1-4277-52810
    Diploma/Master Student
    Bachmair
    5.108/5.109
    Main Building
  • Nesrete Krasnici
    +43-1-4277-52236
    Technician
    Djinovic
    0326
    VBC 5
  • Karl Kuchler
    +43-1-4277-61807
    Group Leader
    Kuchler
    2.111
    Main Building
  • Julius Kühn
    +43-1-4277-54629
    Diploma/Master Student
    Baccarini
    4.525/4.527
    Main Building
  • Peter Kunnas
    +43-1-4277-52292
    PostDoc
    Juffmann
    1.610
    VBC 5
  • Claudia Kuntner
    +43-1-4277-56221
    Klein
    5.528/5.530
    Main Building
  • Patricia-Emanuela Kutin
    +43-1-4277-61606
    Lab Assistant
    3.515
    Main Building
  • L
  • Michael Laichmann
    +43-1-4277-61668
    Diploma/Master Student
    Otsuka
    3.505
    Main Building
  • Karin Ledolter
    +43-1-4277-52260
    Lab Manager
    Konrat
    0122
    VBC 5
  • Martin Leeb
    +43-1-4277-74644
    Group Leader
    Leeb
    3.123/3.125
    Main Building
  • Günther Leitgeb
    +43-1-4277-54633
    IT Management
    4.420
    Main Building
  • Moritz Leitner
    +43-1-4277-61816
    Martinez
    2.512
    Main Building
  • Thomas Lenert
    +43-1-4277-61602
    Administration
    3.115
    Main Building
  • Thomas Leonard
    +43-1-4277-52205
    Group Leader
    Leonard
    1.616
    VBC 5
  • Alina Leuchtenberger
    +43-1-4277-74330
    PhD Student
    v. Haeseler
    1.812.2
    VBC 5
  • Aleksandra Levina
    +43-1-4277-52275
    PhD Student
    Leonard
    1.321
    VBC 5
  • Raffael Lichtenberger
    +43-1-4277-61656
    Technician
    Falk
    1.624
    VBC 5
  • Branislav Lilic
    +43-1-4277-54631
    PhD Student
    Bläsi
    4.122/4.124
    Main Building
  • Sarah Linauer
    +43-1-4277-61704
    Diploma/Master Student
    Ogris
    2.127
    Main Building
  • Josef Loidl
    +43-1-4277-56210
    Group Leader
    Loidl
    5.515
    Main Building
  • Salvo Danilo Lombardo
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • M
  • Moritz Madern
    +43-1-79044-4291
    Technician
    E72
  • Dante Maestre
    +43-1-4277-52213
    PhD Student
    Juffmann
    1.722
    VBC 5
  • Daniel Malzl
    +43-1-4277-74390
    PhD Student
    Menche
    1803
    VBC 5
  • Christina Manakanatas
    +43-1-4277-74644
    PhD Student
    Foisner
    3.123/3.125
    Main Building
  • Richard Manning
    +43-1-4277-54613
    Diploma/Master Student
    Witte
    4.125/4.127
    Main Building
  • Raphaël Marchand
    +43-1-4277-72523
    PostDoc
    Juffmann
    1.614
    VBC 5
  • Mateo Marković
    +43-1-4277-56231
    Diploma/Master Student
    Matos
    5.122/5.123
    Main Building
  • Laura Marosits
    +43-1-4277-61635
    Technician
    Karagöz
    3.507/ 3.508
    Main Building
  • Theodor Marsoner
    +43-1-4277-52808
    PhD Student
    Campbell
    5.512/5.513
    Main Building
  • Sascha Martens
    +43-1-4277-52876
    Group Leader
    Martens
    5.113
    Main Building
  • Javier Martinez
    +43-1-4277-61803
    Group Leader
    Martinez
    2.113
    Main Building
  • Fabien Martins
    +43-1-4277-24010
    Financial Director
    6.107
    Main Building
  • Angela Martins
    +43-1-4277-54601
    Administration
    4.114
    Main Building
  • Joao Matos
    +43-1-4277-74419
    Group Leader
    Matos
    5.024
    Main Building
  • Theresa Matzinger
    +43-1-4277-61761
    Weitzer
    2.522
    Main Building
  • Rounik Mazumdar
    +43-1-4277-61818
    PostDoc
    Kuchler
    2.509
    Main Building
  • Jörg Menche
    +43-1-4277-74370
    Group Leader
    Menche
    1804
    VBC 5
  • Mario Migotti
    +43-1-4277-52263
    PhD Student
    Konrat
    0114
    VBC 5
  • Laurenz Miksch
    +43-1-4277-61656
    Falk
    1.622
    VBC 5
  • Dalibor Milic
    +43-1-4277-52215
    Senior PostDoc
    Djinovic
    1.120
    VBC 5
  • Nadja Milivojev
    +43-1-4277-74636
    PhD Student
    Raible
    4.510/4.512
    Main Building
  • Frane Miljkovic
    +43-1-4277-61643
    PhD Student
    Köhler A
    3.524
    Main Building
  • Milana Mirkovic
    +43-1-4277-52272
    Diploma/Master Student
    Zagrovic
    1.114
    VBC 5
  • Alexandru-Stefan Mixich
    +43-1-4277-24042
    IT Support
    2.116
    Main Building
  • Rozi Mkrtchyan
    +43-1-4277-61823
    Martinez
    2.515
    Main Building
  • Katharina Mohr
    +43-1-4277-61704
    Technician
    Ogris
    2.127
    Main Building
  • Isabella Moll
    +43-1-4277-54606
    Group Leader
    Moll
    4.028
    Main Building
  • Julia Mor Galvez
    +43-1-4277-74636
    Diploma/Master Student
    Tessmar
    4.501
    Main Building
  • Giasemi Angeliki Moraitou
    +43-1-4277-56241
    Diploma/Master Student
    Schlögelhofer
    5.524/5.526
    Main Building
  • Jayma Mostafa
    +43-1-4277-54622
    Diploma/Master Student
    Raible
    4.504/4.506
    Main Building
  • Ingrid Mudrak
    +43-1-4277-61740
    Lab Manager
    Ogris
    2.030
    Main Building
  • Felix Müller
    +43-1-4277-74371
    Senior PostDoc
    Menche
    1104
    VBC 5
  • Ernst Müllner
    +43-1-4277-61783
    Group Leader
    Müllner
    2.523
    Main Building
  • Adnan Muratovic
    +43-1-4277-54614
    Diploma/Master Student
    Versteeg
    4.108
    Main Building
  • N
  • Julia Naas
    +43-1-4277-74328
    PhD Student
    v. Haeseler
    1.812.3
    VBC 5
  • Nana Naetar-Kerenyi
    +43-1-4277-61671
    PostDoc
    Foisner
    3.108
    Main Building
  • Michael Nagy
    +43-1-4277-52263
    Diploma/Master Student
    Djinovic
    0114
    VBC 5
  • Lilian Nehlin
    +43-1-4277-52810
    PostDoc
    Bachmair
    5.108/5.109
    Main Building
  • Siegfried Nemeth
    +43-1-4277-24060
    Technician
    3.501
    Main Building
  • Melissa Neumann
    +43-1-4277-24072
    Facility Staff
    0.116
    Main Building
  • Yap Shing Nim
    +43-1-4277-61649
    PostDoc
    Köhler A
    3.527
    Main Building
  • Tobias Nimpf
    +43-1-4277-61681
    Diploma/Master Student
    Foisner
    3.108
    Main Building
  • Johannes Nimpf
    +43-1-4277-61808
    Group Leader
    Nimpf
    2.112
    Main Building
  • Adrian Nogales Moral
    +43-1-4277-61643
    PhD Student
    Köhler A
    3.524
    Main Building
  • O
  • Michael Oberhuemer
    +43-1-4277-74645
    Technician
    Leeb
    3.123/3.125
    Main Building
  • Helena Oberndorfer
    +43-1-4277-52807
    Diploma/Master Student
    Slade
    5.508
    Main Building
  • Clarissa Obinger
    +43-1-4277-52838
    Diploma/Master Student
    Martens
    5.401
    Main Building
  • Egon Ogris
    +43-1-4277-61730
    Group Leader
    Ogris
    2.127
    Main Building
  • Lukas Orel
    +43-1-4277-74636
    Lab Manager
    Tessmar
    4.501
    Main Building
  • Lucija Orlić
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Shotaro Otsuka
    +43-1-4277-61665
    Group Leader
    Otsuka
    3.506
    Main Building
  • Ö
  • Sidar Özer
    +43-1-4277-24042
    IT Support
    2.116
    Main Building
  • O
  • Pedro Ozorio Brum
    +43-1-4277-74635
    PhD Student
    Tessmar
    4.510/4.512
    Main Building
  • P
  • Claudia Pachinger
    +43-1-4277-54621
    PhD Student
    Dammermann
    4.508
    Main Building
  • Nathan Palmer
    +43-1-4277-56231
    PostDoc
    Matos
    5.122/5.123
    Main Building
  • Dimitra Paouneskou
    +43-1-4277-56261
    PostDoc
    Jantsch V
    5.522
    Main Building
  • Paulina Parafiniuk-Borzecki
    +43-1-4277-52801
    Administration
    5.115
    Main Building
  • Rajvi Shashi Patel
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Julia Pazmandi
    +43-1-4277-74372
    PhD Student
    Menche
    1104
    VBC 5
  • Philipp Penninger
    +43-1-4277-61812
    PhD Student
    Kuchler
    2.107
    Main Building
  • Cassius Manuel Perez de los Cobos Hermosa
    +43-1-4277-74326
    PhD Student
    v. Haeseler
    1.812.5
    VBC 5
  • Lara Veronika Perko Budja
    +43-1-4277-74610
    Diploma/Master Student
    Görke
    4.110
    Main Building
  • Thomas Peterbauer
    +43-1-4277-61676
    Senior Imaging Specialist
    1.618
    VBC 5
  • Vicky Petroulaki
    +43-1-4277-56231
    PhD Student
    Matos
    5.122/5.123
    Main Building
  • Andriy Petryshyn
    +43-1-4277-61812
    Technician
    Kuchler
    2.107
    Main Building
  • Franz Pfanner
    +43-1-4277-74320
    Diploma/Master Student
    Juffmann
    1.812.3
    VBC 5
  • Karin Pfeiffer
    +43-1-4277-52201
    Administration
    1.604
    VBC 5
  • Florian Pflug
    +43-1-4277-74323
    PostDoc
    v. Haeseler
    1.812.1
    VBC 5
  • Trinh Phan-Canh
    +43-1-4277-24001
    Kuchler
    2.509
    Main Building
  • Parvaneh Piran
    +43-1-4277-24004
    Controller
    6.109
    Main Building
  • Sebastian Pirch
    +43-1-4277-74390
    Technician
    Menche
    1803
    VBC 5
  • Marina Pletzer
    +43-1-4277-61656
    PhD Student
    Falk
    1.624
    VBC 5
  • Birgit Poehn
    +43-1-4277-74636
    PhD Student
    Tessmar
    4.501
    Main Building
  • Anton Polyansky
    +43-1-4277-52271
    Staff Scientist
    Zagrovic
    1.612
    VBC 5
  • Niko Popitsch
    +43-1-4277-24024
    Senior PostDoc
    Ameres
    2.116
    Main Building
  • Hauptgebäude Portier
    +43-1-4277-12894
    1.106
    Main Building
  • Elisabeth Prager
    +43-1-4277-54632
    Diploma/Master Student
    Moll
    4.129
    Main Building
  • Viktoria Prast
    +43-1-4277-56221
    PhD Student
    Klein
    5.401
    Main Building
  • Christopher Pree
    +43-1-4277-54628
    Diploma/Master Student
    Decker
    4.522/4.524
    Main Building
  • Silvia Prieler
    +43-1-4277-56221
    PostDoc
    Klein
    5.401
    Main Building
  • Friedrich Propst
    +43-1-4277-52858
    Guest Researcher
    Propst
    5.528/5.530
    Main Building
  • Dominic Pühringer
    +43-1-4277-52225
    PhD Student
    Djinovic
    0612
    VBC 5
  • Q
  • Laura Quell
    +43-1-4277-74610
    PhD Student
    Görke
    4.110
    Main Building
  • R
  • Katarina Radisavljevic
    +43-1-4277-61641
    PhD Student
    Köhler A
    3.522
    Main Building
  • Florian Raible
    +43-1-4277-54616
    Group Leader
    Raible
    4.115
    Main Building
  • Birgit Rapp
    +43-1-4277-54628
    Lab Manager
    Decker
    4.522/4.524
    Main Building
  • Eva Rasch
    +43-1-4277-52820
    Facility Technician
    5.116
    Main Building
  • Sonia Ratajczyk
    +43-1-4277-52862
    PhD Student
    Fuchs
    5.125/5.127
    Main Building
  • Aarathy Ravi sundar Jose Geetha
    +43-1-4277-54628
    PhD Student
    Decker
    4.522/4.524
    Main Building
  • Mihaela Raykova
    +43-1-4277-61653
    Diploma/Master Student
    Karagöz
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    PostDoc
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    Leonard
    1.321
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    PostDoc
    5.10
    IMP/IMBA
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    PostDoc
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    Lab Manager
    Swarts
    1.722.1
    VBC 5
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    PostDoc
    Köhler A
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    Martens
    5.502
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    Facility Staff
    1.117
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    Rotheneder
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    5.522
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    Djinovic
    0326
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    Müllner
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    Juffmann
    1.722.1
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    0124
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    4624
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    1803
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    1.722
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    1.812.2
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    Swarts
    1.722.1
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    4622
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    1803
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    Swarts
    1.722.1
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    2.512
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    1.722.1
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    Zagrovic
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    Main Building
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    PhD Student
    Juffmann
    1.722
    VBC 5

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