During the development of gametes, such as egg and sperm cells in humans, chromosomes are broken and rearranged at many positions. Using state of the art technology, the research group of Franz Klein, professor for genetics at the Max F. Perutz Laboratories of the University of Vienna, has analyzed this process at high resolution. The surprising observations regarding the mechanism of meiosis are now published in the scientific top-journal Cell.
Without meiosis there would be no sexual reproduction, as germ cells have to be generated in this specialized cell division. Meiosis results in daughter cells containing a single, complete set of chromosomes, while body cells contain two sets. During fertilization, when sperm and egg fuse, their sets of chromosomes are combined to form a diploid embryo to close the cycle.
There are 46 chromosomes in every human cell, 23 maternal and 23 paternal ones. When germ cells are produced, one aspect of the reduction in chromosome numbers comes from merging maternal and paternal chromosomes to form a single daughter chromosome – a mechanisms called recombination. “The more we learn about meiosis, the more mysterious it becomes.”, says Franz Klein from the Department for chromosome biology of the University of Vienna. “It is surprising that maternal and paternal chromosomes find each other at all. Because at the time of interaction all chromosomes have generated a sister and are tightly connected with her like a Siamese twin. Normally, in non-meiotic cells, chromosomes only interact and exchange with the sister chromosome. However, during the development of germ cells, only the exchange between parental chromosomes can guarantee the production of daughter cells with the right number of chromosomes.” explains Klein.
Franz Klein and his research team have analyzed components of the protein machinery, which initiates recombination by DNA-breakage. They created a high resolution map of the chromosomes and marked the interaction sites with those proteins. “Thanks to DNA microarray-technology, we get a resolution in the nanometer range, with insights unimaginable before.” says Klein. The researchers were surprised to find the DNA-breaking machine tightly associated with chromosomal axis regions, instead of being soluble - an observation with far reaching consequences.
One of the many riddles in meiosis was how breaks on chromosomes impede the occurrence of other breaks in their vicinity. Earlier research had shown that each individual DNA-breakage complex only works a single time. “As we now know that these machines are anchored, we understand why there is preferentially a single break per region. The locally bound machine has fired and other machines can’t get there as they are anchored to other chromosomal regions”, explains Klein.
Healthy chromosomes can form DNA loops, which are, in meiosis, connected by a protein axis. Defective genes can cause chromosomes to lose this shape. “No one could understand why the shape of chromosomes influences the function of the DNA-break machines. Now we know that these machines have to anchor between loops on the chromosome axis. If their loop-environment changes they anchor in different regions or lose functionality altogether”, says Klein.
Sister chromosomes are connected like Siamese twins along the chromosome axis, where the DNA-break machines are anchored. It was very mysterious, how the sister chromosome is prevented to take part in the repair of DNA breaks during meiosis, despite being so close to the damage. A special feature of meiosis is the formation of a zone along the chromosome axis that inhibits recombination. “We think that the DNA-break machines are anchored at the axis to position the breaks right within the recombination inhibiting zone. This may attract the sister chromosome loop, which remains trapped in the recombination inhibiting zone by one of the two ends flanking the break, while the second end docks off to form a search tentacle for finding the paternal chromosome.”
“We have evidence for many details of this scenario – but most importantly, the inhibition of the involvement of the sister breaks down, if the anchoring of the DNA-break machines is defective. This indicates that anchoring may be indeed a key mechanism to control the sister. The result of a sister, hyperactive for DNA-break repair in meiosis is the death or severe impairment of the developing embryo.
Funding
The published work was conducted within the framework of the Special Research Program F34-“Chromosome Dynamics” of the Austrian Science Fund FWF. Seven research groups of the MFPL and the Institute of Molecular Pathology (IMP) collaborate in this research program to unravel questions of chromosome biology. Coordination: Franz Klein and Jan Michael Peters, this year’s Wittgenstein awardee.
Original publication in Cell:
Silvia Panizza, Marco A. Mendoza, Marc Berlinger, Lingzhi Huang, Alain Nicolas, Katsuhiko Shirahige, Franz Klein (2011) Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination.
Why should life maintain chirality
14:00 - 15:00
ZoomSpeaker: Yossi Paltiel
Institute: The Hebrew University
Host: Thomas Juffmann
Structural investigation of protein secretion by the Salmonella type III secretion system injectisome
09:00 - 10:00 ZoomSpeaker: Sean Miletic
Institute: Marlovits Lab
Monday Seminar (Internal)
12:30 - 13:30 ZoomSpeaker: BATTY Paul Daniel (Gerlich), JACOBS Jelle (Stark), BAUMANN Verena (Martens)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
The deeply conserved miR-1/V-ATPase regulatory axis is essential for muscle physiology
15:00 - 16:00 ZoomSpeaker: Paula Gutiérrez Pérez
Institute: IMP - Cochella Lab
Lanthanide Chelating Tags for Pseudo-contactshift NMR Spectroscopy - Useful Long-range Tools for Structural Biology
14:00 - 15:00 ZoomSpeaker: Daniel Häussinger
Institute: University of Basel
Host: Kristina Djinovic-Carugo
Following neuronal trajectories in developing brain
11:00 - 12:00 ZoomSpeaker: Silvia Cappello
Institute: MPI of Psychiatry Munich
Host: Sofia Grade
Monday Seminar (Internal)
12:30 - 13:30 ZoomSpeaker: RITSCHKA Birgit (Tanaka), LEIENDECKER Lukas (Obenauf), PISUPATI Rahul Bharadwaj (Nordborg)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Haven't got a glue?
11:00 - 12:00 ZoomSpeaker: Nicolas Thomä
Institute: FMI Basel
Host: Jan-Michael Peters
Unraveling the structure of toxic protein aggregates in situ
14:00 - 15:00 ZoomSpeaker: Rubén Fernández-Busnadiego
Institute: MPI of Biochemistry Department of Molecular Structural Biology
Host: Sebastian Falk
Monday Seminar (Internal)
12:30 - 13:30 ZoomSpeaker: VOGEL Antonia (Clausen), INCARBONE Marco (Mittelsten Scheid), TELONI Federico (Gerlich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Sex and gender bias in research: from the test tube to career path
15:00 - 16:00 ZoomSpeaker: Flora Vincent and Aude Bernheim
Institute: Weizmann Institute of Science, Israel and French Institute of Health and Medical Research, INSERM, France
Host: VBC Postdocs
Title to be announced
16:00 - 17:00 ZoomSpeaker: Denis Jabaudon
Institute: Universite de Geneve
Host: SFB Neuro Stem Modulation
Title to be announced
14:00 - 15:00 ZoomSpeaker: Eva Pereiro
Institute: ALBA synchrotron - Experiments Division
Host: Kristina Djinovic-Carugo
TraitMap: linking genes to quantitative cellular traits in haploid cells to study cell biology
11:00 - 12:00 ZoomSpeaker: Thijn Brummelkamp
Institute: Netherlands Cancer Institute
Host: Johannes Zuber
Monday Seminar (Internal)
12:30 - 13:30 ZoomSpeaker: AYALA MUNOZ Farja Isabel (Plaschka), HOLZMANN Viktoria (Rivron), STALTNER Moritz (Ameres)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Switching Genes on and off during development and differentiation
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Doug Higgs
Institute: MRC Weatherall Institute of Medicine
Host: Rushad Pavri
Title to be announced
14:00 - 15:00 ZoomSpeaker: Sten Linarsson
Institute: Karolinska Institute
Host: SFB Neuro Stem Modulation
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: BASSAT Elad (Tanaka), RUANGROENGKULRITH Siwat (Tachibana), DOMBEY Rodolphe (Mari-Ordonez)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Navigating the cellular landscape with new imaging technologies
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Jennifer Lippincott-Schwartz
Institute: Janelia Farm
Host: Kristina Djinovic Carugo
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: FEDL Anna (Busslinger), TERIYAPIROM Isaree (Koo), LI Chong (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
16:00 - 17:00 ZoomSpeaker: Coleen T Murphy
Institute: Princeton University
Host: SFB Neuro Stem Modulation
15th Microsymposium on Small RNAs
Apr 22 - Apr 23This year, the Microsymposium is a two-day international conference that brings together young scientists, junior and senior group leaders from all over the world to present and discuss their latest findings in the exciting field of small RNAs and other RNA biology related topics. The Microsymposium was founded in 2005 and has established itself as the major small RNA meeting in Europe. It is organized by the four research institutions GMI, IMBA, IMP, and Max Perutz Labs, as well as by the RNA community of the Vienna BioCenter.
The Microsymposium is a registration-free meeting for all its participants!
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: LIU Haijun (Nordborg), GEHRE Maja (Brennecke), NEMCKO Filip (Stark)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Visualising the Building Blocks of Life Inside of Cells
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Martin Beck
Institute: MPI of Biophysics
Host: Clemens Plaschka, Shotaro Otsuka
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: NAVALAYEU Tsimafei (Ameres), ZMAJKOVIC Jakub (Zuber), JONSSON Gustav (Penninger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
16:00 - 17:00 ZoomSpeaker: Josh Huang
Institute: Duke University School of Medicine
Host: SFB Neuro Stem Modulation
Title to be announced
11:00 - 12:00 IMP Lecture HallSpeaker: Richard Flavell
Institute: Yale University School of Medicine
Host: Meinrad Busslinger
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Rahul Satija
Institute: New York Genome Center
Host: Andi Pauli
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: HINTERNDORFER Matthias (Zuber), KORESHOVA Alevtina (Burga), REUMANN Daniel (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: NOGALES MORAL Adrian (Köhler), NAJM Ramsey K. (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
14:00 - 15:00 ZoomSpeaker: Grayson Camp
Institute: University of Basel
Host: SFB Neuro Stem Modulation
Regulation of Replication Timing and Chromosome Architecture
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: David Gilbert
Institute: Florida State University
Host: Rushad Pavri
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: CHUGUNOVA Anastasia (Pauli), REITER Franziska (Stark), SGROMO Annamaria (Ameres)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: PHILLIPS Alexander William (Keays), WIDEN Sonya Angeline (Burga), VOICHEK Yoav (Nordborg)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Hitoshi Kurumizaka
Institute: University of Tokyo
Host: Kikue Tachibana
Title to be announced
11:00 - 12:00 IMP Lecture HallSpeaker: Jan Boettcher
Institute: TU Munich
Host: Anna Obenauf
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: RODIRUGEZ TERRONES Diego (Tanaka), KORDIC Darja (Clausen), CRESPO ENRIQUEZ Ivan (Urban)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
16:00 - 17:00 ZoomSpeaker: Miguel Moreno Mateos
Institute: Andalusian Center of Developmental Biology
Host: SFB Neuro Stem Modulation
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Gioacchino Natoli
Institute: Humanitas University
Host: Meinrad Busslinger
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: GARCIA LEON Marta (Dagdas), KLAUS Loni (Stark), JAVALI Alok (Rivron)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: VOICHEK Maya Shinan (Brennecke), PETRZILEK Jan (Ameres), KALIS Robert (Zuber)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Dana Peer
Institute: Memorial Sloan Kettering Cancer Center
Host: Anna Obenauf
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Fanni Gergely
Institute: Cancer Research UK, Cambridge Institute
Host: Alex Dammermann
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: ELEWAUT Anais (Obenauf), ANDRIONE Mara (Zimmer), DAO Pauline (Tessmar)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Valter Longo
Institute: USC Leonard David School of Gerontology
Host: Noelia Urban
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SALAZAR THULA Oriana Ylida (Zimmer), DUKIC Dejan (Nordborg), HANDLER Dominik (Brennecke)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Stefano Di Talia
Institute: Duke University Medical Center
Host: Andi Pauli
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: LEE Du-Hwa (Belkhadir), PACHINGER Claudia (Dammermann lab), BAUMGARTNER Lisa (Brennecke)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: TRASSER Marieke (Mari-Ordonez), GERT Krista (Pauli)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: DE ALMEIDA Melanie (Zuber), BRADAMANTE Gabriele (Mittelsten Scheid), VEEDIN RAJAN Vinoth Babu (Tessmar)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: HARVEY Zachary (Berger), PACHECO FIALLOS Francis Belen (Plaschka), WU Szu-Hsien (Koo)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SESTINI Giovanni (Rivron), MORREALE Francesca (Clausen), PASAJILIC Djurdja (Martinez)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Taekjip Ha
Institute: Johns Hopkins University
Host: Clemens Plaschka
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: CORSI Flavia (Golobordko), BRUNNER Hanna (Haselbach), CRONIN Shona (Obenauf)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Holger Puchta
Institute: Karlsruhe Institute of Technology (KIT)
Host: Ortrun Mittelsten Scheid
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: LEHMANN Christian (Knoblich), MURPHY Paul (Clausen), HISANAGA Tetsuya (Berger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
16:00 - 17:00 ZoomSpeaker: Madeline Lancaster
Institute: MRC Laboratory of Molecular Biology
Host: SFB Neuro Stem Modulation
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Didier Stainier
Institute: MPI for Heart and Lung Research
Host: Elly Tanaka
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SPICER Maximilian (Gerlich), GRÜNBACHER Sarah (Busslinger), BUENDIA Daniel (Mari-Ordonez)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Richard Youle
Institute: NIH
Host: Sascha Martens
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: VERTESY Abel (Knoblich), POLIKARPOVA Anastasia (Tanaka), LEESCH Katrin Friederike (Pauli)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Andrew Dillin
Institute: University of California, Berkeley
Host: Yasin Dagdas
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: PANAROTTO-PERICLES Melanie (Peters), LEE Ho-Soek (Belkhadir), CHAKRABORTY Oisorjo (Grade)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: LEE Ji-Hyun (Koo), PETROVIC Mina (Gerlich), BELACIC Katarina (Haselbach)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Nevan Krogan
Institute: UCSF - Gladstone Institute
Host: Manuela Baccarini
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture Hall Speaker: SHIRZADIAN YAZD Mehrta (Balzarotti), KOLESNIKOVA Sofia (Gerlich), BAUCELLS Julia Garcia (Dammermann)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMP Lecture HallSpeaker: John Diffley
Institute: The Francis Crick Institute
Host: Rushad Pavri, Jan-Michael Peters
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Azim Surani
Institute: Gurdon Institute, University of Cambridge
Host: Andi Pauli
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: HOLSTEIN Felix (Obenauf), KHALDIEH Nina (Ameres), HOHMANN Ulrich (Brennecke/Plaschka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Michael Lichten
Institute: NIH
Host: Peter Schlögelhofer
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: NAVA GARCIA Marintia Mayola (Köhler), TARDIVO Pietro (Tanaka), GEISMANN Maximilian (Balzarotti)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
14:00 - 15:00 ZoomSpeaker: Magdalena Goetz
Institute: LMU Department of Physiological Genomics
Host: SFB Neuro Stem Modulation
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Julia Mahamid
Institute: EMBL
Host: Shamba Saha
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SCHMUECKER Anna (Berger), VOGT Vivien (Zuber), HEIDARI KHOEI Heidar (Rivron)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Alejandro Sanchez Alvarado
Institute: Stowers Inst. for Medical Research
Host: Elly Tanaka
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: ELLIS Thomas (Nordborg), JELENIC Stela (Saha)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMP Lecture HallSpeaker: Patrick Cramer
Institute: MPI for Biophysical Chemistry
Host: Alexander Stark, Clemens Plaschka
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Steve Jackson
Institute: Gurdon Research Institute
Host: Rushad Pavri
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: TREPTE Philipp (Knoblich), ABDRAKHMANOV Alibek (Dagdas), EHRMANN Julian (Clausen)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Adele Marston
Institute: Wellcome Centre Cell Biology, University of Edinburgh
Host: Daniel Gerlich, Joao Matos
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: ROSS James (Brennecke), ISBANER Sebastian (Balzarotti), STREUBEL Susanna (Dolan)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Kai Johnsson
Institute: MPI for Medical Research
Host: Daniel Gerlich
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: JUNKER Sabryna (Clausen), ZHAO Jierui (Dagdas), ISHIHARA Keisuke (Tanaka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMBA/GMI Lecture HallSpeaker: Xin Chen
Institute: Johns Hopkins University
Host: Fred Berger
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: VALLEBUENO Miguel (Swarts), SAJTOS Bettina (Zuber), NAGUMO WONG Sakurako (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: LUST Katharina (Tanaka), CLAVEL Marion (Dagdas), TIKANOVA Polina (Burga)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: CTORTECKA Claudia (Mendjan), MULVEY Hugh (Dolan), LORBEER Franziska (Stark)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SCHELLHAAS Ulla (Plaschka), MEREITER Stefan (Penninger), RADHAKRISHNA PILLAI Balashankar (Saha)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: COLOZZA Gabriele (Koo), BLAHA Andreas (Pauli), PÜHRINGER Florian (Burga)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: JUNG Pauline (Obenauf), LICHT-MAYER Simon (Penninger), CAYGILL Samuel (Dolan)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: FALCON CHAVEZ Francisco Javier (Tanaka), KOK Jian Yi (Berger), VORLÄNDER Matthias (Plaschka)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SODERHOLM Adrian (Versteeg), NEUDOLT Andrea (Obenauf), ANDREEV Veselin (Brennecke)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: HUMER Theresa (Pauli), CECI GINISTRELLI Lavinia (Mendjan), SANCHEZ DE MEDINA HERNANDEZ Victor (Dagdas)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: CORIC Aida (Tessmar), GOGOVA Rebeca (Clausen), LEE Heetak (Koo)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: TAVERNINI Katherina (Urban), CASEY Chloe (Dolan), DOLESCHALL Balint (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: PORTELL I DE MONTSERRAT Julia (Brennecke), ATTRILL Sarah (Dolan), CALDERON DOMINGUEZ Lesly (Busslinger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: REY Ulises (Zimmer), BOURGUET Pierre (Berger), UIJTTEWAAL Esther (Elling)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: BECERRIL PEREZ Fernando (Tanaka), KETTEL Paulina (Karagöz), PUSHPA BOSE Greeshma (Urban)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: DEYETT Alison Ann (Mendjan), FIESLER Charlie (Zimmer), PICCHIANTI Lorenzo (Dagdas)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: VÖLKL Isabella (Bücker), TSAREV Aleksandr (Ameres), GABARRO SOLANAS Rut (Urban)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMP Lecture HallSpeaker: Joan Massague
Institute: Memorial Sloan Kettering Cancer Center
Host: Anna Obenauf
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: AULER Markus (Baccarini), MADHUSUDHANAN Jalaja (Zimmer), SCHENK Robyn (Busslinger)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: DA CUNHA E SILVA MARTINS COSTA Catarina (Knoblich), SHULKINA Alexandra (Versteeg), STOCKINGER Alexander (Raible)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
11:00 - 12:00 IMP Lecture HallSpeaker: Ulrich Hartl
Institute: Max Planck Institute of Biochemistry
Host: Tim Clausen
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: LEE Joonsun (Elling), MILJKOVIC Frane (Köhler), HOFBAUER Lorena (Stark)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: FAHRENBERGER Martin (Von Haeseler), RAUSCHMEIER Rene (Busslinger), GUPTA Ankit (Golobordko)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: SCHMÖLLERL Johannes (Zuber), FAAS Victoria (Clausen), ANISIMOVA Aleksandra (Karagöz)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: BRAGULAT TEIXIDOR Helena (Otsuka), SALEWSKIJ Kirill (Penninger), KAGAWA Harunobu (Rivron)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
12:30 - 13:30 IMP Lecture HallSpeaker: CASEY Alexandra (Dolan), CERRON ALVAN Luis Miguel (Leeb), SIDHAYE Jaydeep (Knoblich)
Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
+43 1 4277 240 01
Today: 9am - 5pm
Vienna Biocenter (VBC)
Dr.-Bohr-Gasse 9, 1030 Vienna