Lipid saturation controls nuclear envelope function.
Romanauska, Anete; Köhler, Alwin
Assembly principle of a membrane-anchored nuclear pore basket scaffold.
Cibulka, Jakub; Bisaccia, Fabio; Radisavljevic, Katarina; Gudino Carrillo, Ricardo M; Köhler, Alwin
Reprogrammed lipid metabolism protects inner nuclear membrane against unsaturated fat.
Romanauska, Anete; Köhler, Alwin
Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: First results from the Austrian School-SARS-CoV-2 prospective cohort study
Willeit, Peter; Krause, Robert; Lamprecht, Bernd; Berghold, Andrea; Hanson, Buck; Stelzl, Evelyn; Stoiber, Heribert; Zuber, Johannes; Heinen, Robert; Köhler, Alwin; Bernhard, David; Borena, Wegene; Doppler, Christian; von Laer, Dorothee; Schmidt, Hannes; Pröll, Johannes; Steinmetz, Ivo; Wagner, Michael
Nuclear envelope lipids request border surveillance.
Köhler, Alwin
Phase separation directs ubiquitination of gene-body nucleosomes
Gallego, Laura D.; Schneider, Maren; Mittal, Chitvan; Romanauska, Anete; Gudino Carrillo, Ricardo M.; Schubert, Tobias; Pugh, B. Franklin; Köhler, Alwin
The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore.
Fischböck-Halwachs, Josef; Singh, Sylvia; Potocnjak, Mia; Hagemann, Götz; Solis-Mezarino, Victor; Woike, Stephan; Ghodgaonkar-Steger, Medini; Weissmann, Florian; Gallego, Laura D; Rojas, Julie; Andreani, Jessica; Köhler, Alwin; Herzog, Franz
The Inner Nuclear Membrane Is a Metabolically Active Territory that Generates Nuclear Lipid Droplets.
Romanauska, Anete; Köhler, Alwin
Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
Gallego, Laura D; Ghodgaonkar Steger, Medini; Polyansky, Anton A; Schubert, Tobias; Zagrovic, Bojan; Zheng, Ning; Clausen, Tim; Herzog, Franz; Köhler, Alwin
Mediator and TREX-2: emerging links between transcription initiation and mRNA export.
Schubert, Tobias; Köhler, Alwin
The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression.
Schneider, Maren; Hellerschmied, Doris; Schubert, Tobias; Amlacher, Stefan; Vinayachandran, Vinesh; Reja, Rohit; Pugh, B Franklin; Clausen, Tim; Köhler, Alwin
Nuclear pore basket proteins are tethered to the nuclear envelope and can regulate membrane curvature.
Mészáros, Noémi; Cibulka, Jakub; Mendiburo, Maria Jose; Romanauska, Anete; Schneider, Maren; Köhler, Alwin
Monoubiquitination of Histone H2B is Intrinsic to the Bre1 RING - Rad6 Interaction and Augmented by a Second Rad6 Binding Site on Bre1.
Turco, Eleonora; Gallego, Laura D; Schneider, Maren; Köhler, Alwin
Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
Ellisdon, Andrew M; Jani, Divyang; Köhler, Alwin; Hurt, Ed; Stewart, Murray
Gene regulation by nucleoporins and links to cancer.
Köhler, Alwin; Hurt, Ed
Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module.
Köhler, Alwin; Zimmerman, Erik; Schneider, Maren; Hurt, Ed; Zheng, Ning
Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Jani, Divyang; Lutz, Sheila; Marshall, Neil J; Fischer, Tamás; Köhler, Alwin; Ellisdon, Andrew M; Hurt, Ed; Stewart, Murray
Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination.
Klöckner, Christoph; Schneider, Maren; Lutz, Sheila; Jani, Divyang; Kressler, Dieter; Stewart, Murray; Hurt, Ed; Köhler, Alwin
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
Köhler, Alwin; Schneider, Maren; Cabal, Ghislain G; Nehrbass, Ulf; Hurt, Ed
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2.
Yao, Wei; Roser, Daniela; Köhler, Alwin; Bradatsch, Bettina; Bassler, Jochen; Hurt, Ed
Dissecting the turgor sensing mechanisms in the blast fungus Magnaporthe oryzae
Pikobodies: What does it take to bioengineer NLR immune receptor-nanobody fusions
scRNA and phylogenetics
Gene regulatory mechanisms governing human development, evolution and variation
Regulation of Cerebral Cortex Morphogenesis by Migrating Cells
Phage therapy for treating bacterial infections: a double-edged sword
Suckers and segments of the octopus arm
Using the house mouse radiation to study the rapid evolution of genes and genetic processes
CRISPR jumps ahead: mechanistic insights into CRISPR-associated transposons
SLiMs and SHelMs: Decoding how short linear and helical motifs direct PPP specificity to direct signaling
Title to be announced
Enigmatic evolutionary origin and multipotency of the neural crest cells - major drivers of vertebrate evolution
Visualising mitotic chromosomes and nuclear dynamics by correlative light and electron microscopy
Engineered nanocarriers for imaging of small proteins by CryoEM
Bacterial cell envelope homeostasis at the (post)transcriptional level
Title to be announced
Hydrologic extremes alter mechanisms and pathways of carbon export from mountainous floodplain soils
Dissecting post-transcriptional gene expression regulation in humans and viruses
Polyploidy and rediploidisation in stressful times
Prdm9 control of meiotic synapsis of homologs in intersubspecific hybrids
Title to be announced
RNA virus from museum specimens
Programmed DNA double-strand breaks during meiosis: Mechanism and evolution
Title to be announced