HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation.
Scinicariello, Sara; Soderholm, Adrian; Schäfer, Markus; Shulkina, Alexandra; Schwartz, Irene; Hacker, Kathrin; Gogova, Rebeca; Kalis, Robert; Froussios, Kimon; Budroni, Valentina; Bestehorn, Annika; Clausen, Tim; Kovarik, Pavel; Zuber, Johannes; Versteeg, Gijs A
Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Ehrmann, Julian F; Grabarczyk, Daniel B; Heinke, Maria; Deszcz, Luiza; Kurzbauer, Robert; Hudecz, Otto; Shulkina, Alexandra; Gogova, Rebeca; Meinhart, Anton; Versteeg, Gijs A; Clausen, Tim
Transient upregulation of IRF1 during exit from naive pluripotency confers viral protection.
Romeike, Merrit; Spach, Stephanie; Huber, Marie; Feng, Songjie; Vainorius, Gintautas; Elling, Ulrich; Versteeg, Gjis A; Buecker, Christa
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida, Melanie; Hinterndorfer, Matthias; Brunner, Hanna; Grishkovskaya, Irina; Singh, Kashish; Schleiffer, Alexander; Jude, Julian; Deswal, Sumit; Kalis, Robert; Vunjak, Milica; Lendl, Thomas; Imre, Richard; Roitinger, Elisabeth; Neumann, Tobias; Kandolf, Susanne; Schutzbier, Michael; Mechtler, Karl; Versteeg, Gijs A; Haselbach, David; Zuber, Johannes
Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner.
Watzenboeck, Martin L; Drobits, Barbara; Zahalka, Sophie; Gorki, Anna-Dorothea; Farhat, Asma; Quattrone, Federica; Hladik, Anastasiya; Lakovits, Karin; Richard, Gabriel M; Lederer, Therese; Strobl, Birgit; Versteeg, Gijs A; Boon, Louis; Starkl, Philipp; Knapp, Sylvia
Negative Regulation of the Innate Immune Response through Proteasomal Degradation and Deubiquitination.
Budroni, Valentina; Versteeg, Gijs A
A repetitive acidic region contributes to the extremely rapid degradation of the cell-context essential protein TRIM52.
Hacker, Kathrin; Benke, Stefan; Agerer, Benedikt; Scinicariello, Sara; Budroni, Valentina; Versteeg, Gijs A
Human tripartite motif protein 52 is required for cell context-dependent proliferation
Benke, Stefan; Agerer, Benedikt; Haas, Lisa; Stöger, Martin; Lercher, Alexander; Gabler, Lisa; Kiss, Izabella; Scinicariello, Sara; Berger, Walter; Bergthaler, Andreas; Obenauf, Anna C and Versteeg, Gijs A.
Ubiquitin enzymes in the regulation of immune responses.
Ebner, Petra; Versteeg, Gijs A; Ikeda, Fumiyo
InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins.
Versteeg, Gijs A; Benke, Stefan; García-Sastre, Adolfo; Rajsbaum, Ricardo
Negative regulation of NF-κB activity by brain-specific TRIpartite Motif protein 9.
Shi, Mude; Cho, Hyelim; Inn, Kyung-Soo; Yang, Aerin; Zhao, Zhen; Liang, Qiming; Versteeg, Gijs A; Amini-Bavil-Olyaee, Samad; Wong, Lai-Yee; Zlokovic, Berislav V; Park, Hee-Sung; García-Sastre, Adolfo; Jung, Jae U
Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response.
Rajsbaum, Ricardo; Versteeg, Gijs A; Schmid, Sonja; Maestre, Ana M; Belicha-Villanueva, Alan; Martínez-Romero, Carles; Patel, Jenish R; Morrison, Juliet; Pisanelli, Giuseppe; Miorin, Lisa; Laurent-Rolle, Maudry; Moulton, Hong M; Stein, David A; Fernandez-Sesma, Ana; tenOever, Benjamin R; García-Sastre, Adolfo
TRIMmunity: The Roles of the TRIM E3-Ubiquitin Ligase Family in Innate Antiviral Immunity.
Rajsbaum, Ricardo; García-Sastre, Adolfo; Versteeg, Gijs A
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.
Versteeg, Gijs A; Rajsbaum, Ricardo; Sánchez-Aparicio, Maria Teresa; Maestre, Ana M; Valdiviezo, Julio; Shi, Mude; Inn, Kyung-Soo; Fernandez-Sesma, Ana; Jung, Jae; García-Sastre, Adolfo
HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells.
Oudshoorn, Diede; van Boheemen, Sander; Sánchez-Aparicio, Maria Teresa; Rajsbaum, Ricardo; García-Sastre, Adolfo; Versteeg, Gijs A
Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers.
Oudshoorn, Diede; Versteeg, Gijs A; Kikkert, Marjolein
Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.
Rajsbaum, Ricardo; Albrecht, Randy A; Wang, May K; Maharaj, Natalya P; Versteeg, Gijs A; Nistal-Villán, Estanislao; García-Sastre, Adolfo; Gack, Michaela U
Influenza virus and interferons.
Gijs A. Versteeg and Adolfo García-Sastre
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Mata, Miguel A; Satterly, Neal; Versteeg, Gijs A; Frantz, Doug; Wei, Shuguang; Williams, Noelle; Schmolke, Mirco; Peña-Llopis, Samuel; Brugarolas, James; Forst, Christian V; White, Michael A; García-Sastre, Adolfo; Roth, Michael G; Fontoura, Beatriz M A
From chromosome folding by loop extrusion to anti-plasmid nucleases in bacteria
Identifying and exploiting cell-state dependent metabolic programs
Mind matters. VBC mental health awareness
Chromosomes as Mechanical Objects: from E.coli to Meiosis to Mammalian cells
Convergent evolution of CO2-fixing liquid-liquid phase separation
New ways of leading: inclusive leadership and revising academic hierarchies
Title to be announced
Decoding Molecular Plasticity in the Dark Proteome of the Nuclear Pore Complex
Neurodiversity in academia
Title to be announced