Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Rasool, Reyaz Ur; O'Connor, Caitlin M; Das, Chandan Kanta; Alhusayan, Mohammed; Verma, Brijesh Kumar; Islam, Sehbanul; Frohner, Ingrid E; Deng, Qu; Mitchell-Velasquez, Erick; Sangodkar, Jaya; Ahmed, Aqila; Linauer, Sarah; Mudrak, Ingrid; Rainey, Jessica; Zawacki, Kaitlin P; Suhan, Tahra K; Callahan, Catherine G; Rebernick, Ryan; Natesan, Ramakrishnan; Siddiqui, Javed; Sauter, Guido; Thomas, Dafydd; Wang, Shaomeng; Taylor, Derek J; Simon, Ronald; Cieslik, Marcin; Chinnaiyan, Arul M; Busino, Luca; Ogris, Egon; Narla, Goutham; Asangani, Irfan A
PP2A Rts1 antagonizes Rck2-mediated hyperosmotic stress signaling in yeast
Hollenstein, D M; Veis, J; Romanov, N; Gérecová, G; Ogris, E; Hartl, M; Ammerer, G; Reiter, W
The expression, localisation and interactome of pigeon CRY2.
Balay, Spencer D; Hochstoeger, Tobias; Vilceanu, Alexandra; Malkemper, E Pascal; Snider, William; Dürnberger, Gerhard; Mechtler, Karl; Schuechner, Stefan; Ogris, Egon; Nordmann, Gregory C; Ushakova, Lyubov; Nimpf, Simon; Keays, David A
A phosphatase-centric mechanism drives stress signaling response.
Hollenstein, David Maria; Gérecová, Gabriela; Romanov, Natalie; Ferrari, Jessica; Veis, Jiri; Janschitz, Marion; Beyer, Reinhard; Schüller, Christoph; Ogris, Egon; Hartl, Markus; Ammerer, Gustav; Reiter, Wolfgang
The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor.
Hochstoeger, Tobias; Al Said, Tarek; Maestre, Dante; Walter, Florian; Vilceanu, Alexandra; Pedron, Miriam; Cushion, Thomas D; Snider, William; Nimpf, Simon; Nordmann, Gregory Charles; Landler, Lukas; Edelman, Nathaniel; Kruppa, Lennard; Dürnberger, Gerhard; Mechtler, Karl; Schuechner, Stefan; Ogris, Egon; Malkemper, E Pascal; Weber, Stefan; Schleicher, Erik; Keays, David A
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer, Johanna E; Enzler, Florian; Feichtner, Andreas; Röck, Ruth; Fleischmann, Jakob; Raffeiner, Andrea; Tschaikner, Philipp; Ogris, Egon; Huber, Roland G; Hartl, Markus; Schneider, Rainer; Troppmair, Jakob; Torres-Quesada, Omar; Stefan, Eduard
Selective PP2A Enhancement through Biased Heterotrimer Stabilization.
Leonard, Daniel; Huang, Wei; Izadmehr, Sudeh; O'Connor, Caitlin M; Wiredja, Danica D; Wang, Zhizhi; Zaware, Nilesh; Chen, Yinghua; Schlatzer, Daniela M; Kiselar, Janna; Vasireddi, Nikhil; Schüchner, Stefan; Perl, Abbey L; Galsky, Matthew D; Xu, Wenqing; Brautigan, David L; Ogris, Egon; Taylor, Derek J; Narla, Goutham
PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation.
Frohner, Ingrid E; Mudrak, Ingrid; Schüchner, Stefan; Anrather, Dorothea; Hartl, Markus; Sontag, Jean-Marie; Sontag, Estelle; Wadzinski, Brian E; Preglej, Teresa; Ellmeier, Wilfried; Ogris, Egon
A high sensitivity ZENK monoclonal antibody to map neuronal activity in Aves.
Nordmann, Gregory Charles; Malkemper, Erich Pascal; Landler, Lukas; Ushakova, Lyubov; Nimpf, Simon; Heinen, Robert; Schuechner, Stefan; Ogris, Egon; Keays, David Anthony
Antibodies recognizing the C terminus of PP2A catalytic subunit are unsuitable for evaluating PP2A activity and holoenzyme composition.
Frohner, Ingrid E; Mudrak, Ingrid; Kronlachner, Stephanie; Schüchner, Stefan; Ogris, Egon
The Myc tag monoclonal antibody 9E10 displays highly variable epitope recognition dependent on neighboring sequence context.
Schüchner, Stefan; Behm, Christian; Mudrak, Ingrid; Ogris, Egon
Ca2+-dependent demethylation of phosphatase PP2Ac promotes glucose deprivation-induced cell death independently of inhibiting glycolysis.
Lee, Ha Yin; Itahana, Yoko; Schuechner, Stefan; Fukuda, Masahiro; Je, H Shawn; Ogris, Egon; Virshup, David M; Itahana, Koji
Specificity of research antibodies: "trust is good, validation is better".
Ogris, Egon; Sontag, Estelle; Wadzinski, Brian; Narla, Goutham
Anti-RAINBOW dye-specific antibodies as universal tools for the visualization of prestained protein molecular weight markers in Western blot analysis.
Schüchner, Stefan; Andorfer, Peter; Mudrak, Ingrid; Ogris, Egon
Protein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome Degradation.
Yabe, Ryotaro; Miura, Akane; Usui, Tatsuya; Mudrak, Ingrid; Ogris, Egon; Ohama, Takashi; Sato, Koichi
The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways.
Tscherner, Michael; Zwolanek, Florian; Jenull, Sabrina; Sedlazeck, Fritz J; Petryshyn, Andriy; Frohner, Ingrid E; Mavrianos, John; Chauhan, Neeraj; von Haeseler, Arndt; Kuchler, Karl
Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum.
Montgomery, Therese R; Steinkellner, Thomas; Sucic, Sonja; Koban, Florian; Schüchner, Stefan; Ogris, Egon; Sitte, Harald H; Freissmuth, Michael
Genotoxic Stress Prevents Ndd1-Dependent Transcriptional Activation of G2/M-Specific Genes in Saccharomyces cerevisiae.
Yelamanchi, Syam Kumar; Veis, Jiri; Anrather, Dorothea; Klug, Helene; Ammerer, Gustav
Budding Yeast Greatwall and Endosulfines Control Activity and Spatial Regulation of PP2A(Cdc55) for Timely Mitotic Progression.
Juanes, Maria Angeles; Khoueiry, Rita; Kupka, Thomas; Castro, Anna; Mudrak, Ingrid; Ogris, Egon; Lorca, Thierry; Piatti, Simonetta
Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation.
Romanov, Julia; Walczak, Marta; Ibiricu, Iosune; Schüchner, Stefan; Ogris, Egon; Kraft, Claudine; Martens, Sascha
18th Microsymposium on RNA Biology
The „Microsymposium on RNA Biology“ is an international conference that brings together young scientists, junior and senior group leaders, and company representatives from all over the world to present and discuss their latest findings in the exciting field of small RNAs and beyond. The Microsymposium was founded in 2005 and has established itself as the major small RNA meeting in Europe. It is organized by the four research institutions IMBA, IMP, GMI and the Max Perutz Labs as well as by the RNA community of the Vienna BioCenter.
Nickel impact on human health, from bacterial infections to cancer
Multiscale plant bioimaging using advanced microscopy
Parthenogenesis, cryptobiosis, and the survival in extreme environmental conditions
Evading ageing: Mitochondrial and proteostatic adaptations in oocytes
Genomes in Rhodnius prolixus symbiotic system
Stem cells, immune evasion and metastasis in colorectal cancer
Ubiquitin & Friends Symposium 2024
The Ubiquitin & Friends Symposium is an annual international meeting taking place in the beautiful capital of Austria, aiming to bring together scholars from various fields studying ubiquitin/Ubl biology and protein degradation in a personal, family-like atmosphere, as suggested by the name.
The evolution and development of mollusc shells
Unraveling the Complexity of Crossover Regulation in C. elegans
Dynamics of 3D Genome Structure and Function
How superworms can help to solve our plastic waste crisis
Title to be announced
New players in an old pathway: biology of methanogens of the TACK superphylum
Shaping morphogen gradients: from molecules to tissues and back
Title to be announced
Studying stressed cells by in situ structural biology
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Arbuscular mycorrhiza development and function
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
The unanticipated roles of PICIs and phages in bacterial evolution
Chemical targeting of subcellular protein localization
Origin and diversification of gut-derived organs in chordates
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Connections between carbon and nitrogen cycling in the ocean
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
Striking physiology and cell biology of (marine) environmental microorganisms
Mechanisms controlling maintenance of cohesin dependent loops
Title to be announced