Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria.
Manakanatas, Christina; Ghadge, Santhosh Kumar; Agic, Azra; Sarigol, Fatih; Fichtinger, Petra; Fischer, Irmgard; Foisner, Roland; Osmanagic-Myers, Selma
Lamina-associated polypeptide 2? is required for intranuclear MRTF-A activity.
Sidorenko, Ekaterina; Sokolova, Maria; Pennanen, Antti P; Kyheröinen, Salla; Posern, Guido; Foisner, Roland; Vartiainen, Maria K
LAP2α preserves genome integrity through assisting RPA deposition on damaged chromatin.
Bao, Kaiwen; Zhang, Qi; Liu, Shuai; Song, Nan; Guo, Qiushi; Liu, Ling; Tian, Shanshan; Hao, Jihui; Zhu, Yi; Zhang, Kai; Ai, Ding; Yang, Jie; Yao, Zhi; Foisner, Roland; Shi, Lei
Cytoplasmic keratins couple with and maintain nuclear envelope integrity in colonic epithelial cells.
Stenvall, Carl-Gustaf A; Nyström, Joel H; Butler-Hallissey, Ciarán; Jansson, Theresia; Heikkilä, Taina R H; Adam, Stephen A; Foisner, Roland; Goldman, Robert D; Ridge, Karen M; Toivola, Diana M
LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior.
Naetar, Nana; Georgiou, Konstantina; Knapp, Christian; Bronshtein, Irena; Zier, Elisabeth; Fichtinger, Petra; Dechat, Thomas; Garini, Yuval; Foisner, Roland
Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair.
Moser, Bernhard; Basílio, José; Gotzmann, Josef; Brachner, Andreas; Foisner, Roland
Editorial for the SEB florence special issue: functional organisation of the nuclear periphery.
Evans, David E; Graumann, Katja; Foisner, Roland
The structural and gene expression hypotheses in laminopathic diseases-not so different after all.
Osmanagic-Myers, Selma; Foisner, Roland
Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse.
Osmanagic-Myers, Selma; Kiss, Attila; Manakanatas, Christina; Hamza, Ouafa; Sedlmayer, Franziska; Szabo, Petra L; Fischer, Irmgard; Fichtinger, Petra; Podesser, Bruno K; Eriksson, Maria; Foisner, Roland
Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells.
Vidak, Sandra; Georgiou, Konstantina; Fichtinger, Petra; Naetar, Nana; Dechat, Thomas; Foisner, Roland
Editorial overview: The cell nucleus: New discoveries on nuclear structure, dynamics and function.
Foisner, Roland; Straight, Aaron F
Lamins in the nuclear interior - life outside the lamina.
Naetar, Nana; Ferraioli, Simona; Foisner, Roland
Nuclear envelope localization of LEMD2 is developmentally dynamic and lamin A/C dependent yet insufficient for heterochromatin tethering.
Thanisch, Katharina; Song, Congdi; Engelkamp, Dieter; Koch, Jeannette; Wang, Audrey; Hallberg, Einar; Foisner, Roland; Leonhardt, Heinrich; Stewart, Colin L; Joffe, Boris; Solovei, Irina
Degradation-mediated protein quality control at the inner nuclear membrane.
Boban, Mirta; Foisner, Roland
Molecular insights into the premature aging disease progeria.
Vidak, Sandra; Foisner, Roland
Cdc48 and Ubx1 participate in an inner nuclear membrane associated degradation pathway that governs the turnover of Asi1.
Pantazopoulou, Marina; Boban, Mirta; Foisner, Roland; Ljungdahl, Per O
Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals.
Zlopasa, Livija; Brachner, Andreas; Foisner, Roland
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha.
Gesson, Kevin; Rescheneder, Philipp; Skoruppa, Michael P; von Haeseler, Arndt; Dechat, Thomas; Foisner, Roland
The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis.
Braun, Juliane; Meixner, Arabella; Brachner, Andreas; Foisner, Roland
Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes.
Loi, Manuela; Cenni, Vittoria; Duchi, Serena; Squarzoni, Stefano; Lopez-Otin, Carlos; Foisner, Roland; Lattanzi, Giovanna; Capanni, Cristina
From chromosome folding by loop extrusion to anti-plasmid nucleases in bacteria
Identifying and exploiting cell-state dependent metabolic programs
Mind matters. VBC mental health awareness
Chromosomes as Mechanical Objects: from E.coli to Meiosis to Mammalian cells
Convergent evolution of CO2-fixing liquid-liquid phase separation
New ways of leading: inclusive leadership and revising academic hierarchies
Title to be announced
Decoding Molecular Plasticity in the Dark Proteome of the Nuclear Pore Complex
Neurodiversity in academia
Title to be announced