FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics.
Stok, Colin; Tsaridou, Stavroula; van den Tempel, Nathalie; Everts, Marieke; Wierenga, Elles; Bakker, Femke J; Kok, Yannick; Alves, Inês Teles; Jae, Lucas T; Raas, Maximilian W D; Huis In 't Veld, Pim J; de Boer, H Rudolf; Bhattacharya, Arkajyoti; Karanika, Eleftheria; Warner, Harry; Chen, Mengting; van de Kooij, Bert; Dessapt, Julien; Ter Morsche, Lars; Perepelkina, Polina; Fradet-Turcotte, Amelie; Guryev, Victor; Tromer, Eelco C; Chan, Kok-Lung; Fehrmann, Rudolf S N; van Vugt, Marcel A T M
Estimation of microtubule-generated forces using a DNA origami nanospring.
Nick Maleki, Ali; Huis In 't Veld, Pim J; Akhmanova, Anna; Dogterom, Marileen; Volkov, Vladimir A
Structure of the human FERRY Rab5 effector complex
Quentin, Dennis; Schuhmacher, Jan S.; Klink, Björn U.; Lauer, Jeni; Shaikh, Tanvir R.; Huis in t Veld, Pim J.; Welp, Luisa M.; Urlaub, Henning; Zerial, Marino; Raunser, Stefan
The Structural Flexibility of MAD1 Facilitates the Assembly of the Mitotic Checkpoint Complex
Chen, Chu; Piano, Valentina; Alex, Amal; Han, Simon J. Y.; Huis In t Veld, Pim J; Roy, Babhrubahan; Musacchio, Andrea; Joglekar, Ajit P.
Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
Polley, Soumitra; Müschenborn, Helen; Terbeck, Melina; Antoni, Anna De; Vetter, Ingrid R.; Dogterom, Marileen; Musacchio, Andrea; Volkov, Vladimir A.; Huis in t Veld, Pim J.
Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes.
Huis In 't Veld, Pim J; Wohlgemuth, Sabine; Koerner, Carolin; Müller, Franziska; Janning, Petra; Musacchio, Andrea
Strain stiffening of Ndc80 complexes attached to microtubule plus ends.
Schwietert, Felix; Volkov, Vladimir A; Huis In 't Veld, Pim J; Dogterom, Marileen; Musacchio, Andrea; Kierfeld, Jan
CDC20 assists its catalytic incorporation in the mitotic checkpoint complex.
Piano, Valentina; Alex, Amal; Stege, Patricia; Maffini, Stefano; Stoppiello, Gerardo A; Huis In 't Veld, Pim J; Vetter, Ingrid R; Musacchio, Andrea
Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint.
Allan, Lindsey A; Camacho Reis, Magda; Ciossani, Giuseppe; Huis In 't Veld, Pim J; Wohlgemuth, Sabine; Kops, Geert Jpl; Musacchio, Andrea; Saurin, Adrian T
Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling.
Huis In 't Veld, Pim J; Volkov, Vladimir A; Stender, Isabelle D; Musacchio, Andrea; Dogterom, Marileen
The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.
Ciossani, Giuseppe; Overlack, Katharina; Petrovic, Arsen; Huis In 't Veld, Pim J; Koerner, Carolin; Wohlgemuth, Sabine; Maffini, Stefano; Musacchio, Andrea
Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces.
Volkov, Vladimir A; Huis In 't Veld, Pim J; Dogterom, Marileen; Musacchio, Andrea
Machine Learning Enabled Pooled Optical Screening for Target Discovery in Human Cellular Disease Models
The evolution and development of mollusc shells
Unraveling the Complexity of Crossover Regulation in C. elegans
Dynamics of 3D Genome Structure and Function
How superworms can help to solve our plastic waste crisis
Title to be announced
New players in an old pathway: biology of methanogens of the TACK superphylum
Targeting a gerozyme to reverse muscle aging and increase healthspan
Shaping morphogen gradients: from molecules to tissues and back
Title to be announced
Studying stressed cells by in situ structural biology
The role of non-canonical double strand break repair pathways in genome stability and diversity
Exploring Microbial Resilience: Unravelling Escherichia coliand#x27;s Stress Response at the Level of Protein Synthesis
Arbuscular mycorrhiza development and function
Deep homology and deep diversity: Evolving genetic toolkits for making and sensing light
The evolution of cell type identity and tissue microecology at the fetal-maternal interface
The unanticipated roles of PICIs and phages in bacterial evolution
Chemical targeting of subcellular protein localization
Origin and diversification of gut-derived organs in chordates
Job's Dilemma for the Genome: Why Bad Things Happen to Good Chromosomes
Connections between carbon and nitrogen cycling in the ocean
Understanding how the DNA-loop-extruding protein complex Condensin folds a chromatinized genome into mitotic chromosomes
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
From Roads to Rivers? Occurrence and environmental fate of tire and road wear particles and of tire-related chemicals
FENS 2024 Satellite event: Home cage behavior monitoring at the interface of animal welfare and neuroscience
A mechanism for protein complex regulation at the mitochondrial surface
Striking physiology and cell biology of (marine) environmental microorganisms
Mechanisms controlling maintenance of cohesin dependent loops
Title to be announced