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One of the most intricate and fundamental processes of life is the translation of the genetic code into proteins. Decoding mRNA-based information into the corresponding sequence of amino acids is performed by a complex ribonucleoprotein particle, the ribosome. Traditionally, the ribosome is viewed as a highly conserved machinery with an invariable RNA and protein complement. This perception of invariance has been perpetuated by the determination of high-resolution structures, which implied that ribosomes are homogeneous entities that are not considered to have an intrinsic regulatory capacity. In my group, we aim to challenge this assumption and to decipher mechanisms in bacteria that modulate the translational program by ribosome heterogeneity. In particular, we focus on modifications of ribosomal RNAs and proteins that alter ribosome specificity in response to environmental stress.
We address the phenomenon of ribosome heterogeneity and reprogramming of protein synthesis in vivo and in vitro employing a multifaceted approach combining state-of-the-art methods of molecular biology and bacterial physiology using the model organism Escherichia coli. We further complement our studies with structural analyses to gain detailed insights into the molecular basis of ribosome heterogeneity and specificity. As the sites of modifications are expected to be pivotal for pathogenic bacteria to survive and to recover from stress encountered during host infection, they might represent novel targets for the future design of antimicrobials.
Isabella Moll received her doctorate in microbiology in 2000 from the University of Vienna. After her postdoctoral research, Isabella received the Hertha-Firnberg Award in 2005 allowing her to become independent investigator at the Centre of Molecular Biology, Vienna. In 2017, she was appointed as professor for molecular bacteriology at the Max Perutz Labs.
We have identified a novel post-transcriptional stress response in E. coli that is based on the functional specialisation of ribosomes. The stress-activated endoribonuclease MazF targets the 16S rRNA in the context of the ribosome and removes its functionally important 3´-terminus. These modified ribosomes exclusively translate distinct mRNAs causing a rapid modulation of the translational program.
Recently, we provided evidence for the regeneration of the specialized ribosomes during recovery from stress. The truncated 16S rRNA is repaired in the context of the ribosome by the activity of the RNA ligase RtcB. These results raise the ribosome from the mere protein synthesis machinery to a regulatory hub, which can integrate environmental cues in the process of protein synthesis.
In E. coli and most likely all Gram-negative bacteria, ribosomal protein S1 is pivotal for translation initiation. Recently, we have elucidated the interaction surface between the N-terminal domain of S1 and the ribosome at atomic resolution. Our data suggest novel mechanisms that modulate protein synthesis in response to environmental cues by changing the affinity of S1 for the ribosome.
The RNA ligase RtcB reverses MazF-induced ribosome heterogeneity in Escherichia coli.
Temmel, Hannes; Müller, Christian; Sauert, Martina; Vesper, Oliver; Reiss, Ariela; Popow, Johannes; Martinez, Javier; Moll, Isabella
The MazF-regulon: a toolbox for the post-transcriptional stress response in Escherichia coli.
Sauert, Martina; Wolfinger, Michael T; Vesper, Oliver; Müller, Christian; Byrgazov, Konstantin; Moll, Isabella
Selective Translation of Leaderless mRNAs by Specialized Ribosomes Generated by MazF in Escherichia coli.
Vesper, Oliver; Amitai, Shahar; Belitsky, Maria; Byrgazov, Konstantin; Kaberdina, Anna Chao; Engelberg-Kulka, Hanna; Moll, Isabella
The Group Moll participates in the special Doctoral Program "RNA Biology" reviewed and funded by the Austrian Research Fund FWF.
The Group Moll participates in the Special Research Area (SFB) "RNA-Reg - RNA regulation of the transcriptome" funded by the Austrian Science Fund FWF. SFB's are peer-reviewed, highly interactive research networks, established to foster long-term, interdisciplinary co-operation of local research groups working on the frontiers of their thematic areas.
Breathing at High Altitude
“Breathing at High Altitude” is an exhibition dedicated to the personal life and science of Max F. Perutz, a pioneer of 20thcentury molecular biology. The exhibition sheds light on Max Perutz’s fascinating life, celebrates his love for mountains, and visualizes “breathing” in a unique way. It will be a rewarding experience for scientists and non-scientists alike.
May 19 – June 15 Mon – Fri 9:00 – 18:00 University of Vienna, Inner court (Arkadenhof), Universitätsring 1, 1010 Vienna
Identifying new disease-related mechanisms for genetic cardiomyopathy
Speaker: Eva van RooijInstitute: Hubrecht InstituteHost: Sasha Mendjan
Monday Seminar (Internal)
Speaker: SCHMÖLLERL Johannes (Zuber), FAAS Victoria (Clausen), ANISIMOVA Aleksandra (Karagöz)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Max Perutz: a not so quiet life
Max Perutz’ scientific journey from the Theresianum in Vienna to the Cavendish Laboratory in Cambridge arguably laid the foundations of modern molecular biology. Awarded the Nobel Prize in 1962 for his work on hemoglobin, Max’ legacy continues today at the research institute that bears his name in the city where he was born.
You will hear about Max’ natural curiosity, the scientific question that he dedicated most of his life to answering - how does hemoglobin transport oxygen? - and the tireless perseverance required to achieve his goal.
Plant Phenomics and Epigenomics at Population Scale".
Speaker: Patrick HütherInstitute: GMI
Gene transcription: from mechanisms to regulation
Speaker: Patrick CramerInstitute: MPI for Biophysical ChemistryHost: Alex Stark, Clemens Plaschka
A detailed analysis of the (static and dynamic) local conformations of proteins
Speaker: Alexandre G de BrevernInstitute: INSERM - French National Institute of Health and Medical ResearchHost: Oliviero Carugo
The genetic basis for diversification of leaf form: from understanding to reconstructing
Speaker: Miltos TsiantisInstitute: MPI for Plant Breeding ResearchHost: Yasin Dagdas
HistONe and HistOFF: Measuring Nucleosome Exchange Dynamics
Speaker: Gilad YaakovInstitute: Weizmann Institute of Science, RehovotHost: Fred Berger
Molecular mechanism and folding dynamics of large non-coding RNAs
Speaker: Marco MarciaInstitute: EMBL GrenobleHost: Kristina Djinovic-Carugo
Microbial Storage Compounds
Speaker: Michaela DippoldInstitute: Georg-August-Universität GöttingenHost: Andreas Richter, Wolfgang Wanek
Genomic and developmental features of the sea anemone Nematostella vectensis - insights into the evolution of Bilateria
Speaker: Uli TechnauInstitute: University of Vienna
Remembering who we are: how chromatin controls cell identity
Speaker: Susan GasserInstitute: University of Lausanne
Monday Seminar (Internal)
Speaker: BRAGULAT TEIXIDOR Helena (Otsuka), SALEWSKIJ Kirill (Penninger), KAGAWA Harunobu (Rivron)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Understanding the genetic basis of adaptation to changing climate
Speaker: Kelly SwartsInstitute: GMI
German translation of "Max Perutz and the Secret of Life" by Georgina Ferry
On the occasion of the newly published German translation of the biography "Max Perutz and the Secret of Life", the Austrian Academy of Sciences together with the Max Perutz Labs invite to the presentation of the book including a discussion.
From Basic Biology and CRISPR screening to public health and SARS-CoV-2 sequencing
Speaker: Uli EllingInstitute: IMBA
Single-cell and population mechanisms controlling neural stem cell maintenance in the zebrafish adult brain
Speaker: Laure Bally-CuifInstitute: Institut Pasteur and CNRS UMR3738Host: SFB Neuro Stem Modulation
Proteasomes in action - mechanisms and distribution of human proteasomes
Speaker: David HaselbachInstitute: IMP
Monday Seminar (Internal)
Speaker: CASEY Alexandra (Dolan), CERRON ALVAN Luis Miguel (Leeb), SIDHAYE Jaydeep (Knoblich)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Dual inhibition of angiotensin-converting enzyme (ACE) and neprilysin - a potential new therapy for hypertension and heart failure
Speaker: Ed SturrockInstitute: University of KapstadtHost: Tim Skern
RNA-protein interactions and the structure of the genetic code
Speaker: Bojan ZagrovicInstitute: Max Perutz Labs
Antarctic Research on Methane Production in Oxygenated Waters in Ice Covered Lakes
Speaker: Wei LiInstitute: Lawrence Livermore National LaboratoryHost: Christopher Sedlacek
Structural insights into tail-anchored membrane protein biogenesis by the GET insertase complex
Speaker: Melanie McDowellInstitute: MPI for BiophysicsHost: Sebastian Falk
Imaging processes of cell division across scales
Speaker: Jan EllenbergInstitute: EMBL HeidelbergHost: Shotaro Otsuka
Monday Seminar (Internal)
Speaker: LOUBIERE Vincent (Stark), NGUYEN Vu (Mittelsten Scheid), STANKUNAS Edvinas (Köhler)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Jan-Michael PetersInstitute: IMP
Virus-host strategies to gain the upper hand during infections
Speaker: Gus VersteegInstitute: Max Perutz Labs
Leveraging the patient as the model to dissect and target metastasis
Speaker: Karuna GaneshInstitute: Sloan Kettering InstituteHost: Anna Obenauf
Mechanism of MCM helicase loading and regulation by CDK revealed by cryo-EM
Speaker: Tom MillerInstitute: University of CopenhagenHost: Clemens Plaschka
Life at Nature Genetics: what we do, how scientific publishing works, and how I got here
Speaker: Michael FletcherInstitute: Editor at Nature GeneticsHost: Alex Stark
Long-term single-cell quantification: New tools for old questions
Speaker: Timm SchroederInstitute: ETH ZurichHost: Manuela Baccarini
Cell competition: a paradigm to understand growth control and heterogeneity in complex tissues
Speaker: Stephanie EllisInstitute: Max Perutz Labs
Title to be announced
Speaker: Noelia UrbanInstitute: IMBA
Monday Seminar (Internal)
Speaker: LEYVA GONZALEZ Marco (Tanaka), MILJKOVIC Frane (Köhler), PINTER Theresa (Busslinger)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Andreas MartinInstitute: University of California, BerkeleyHost: David Haselbach
Title to be announced
Speaker: Alexey AmuntsInstitute: Science for Life Laboratory, Stockholm UniversityHost: Silvia Ramundo
Monday Seminar (Internal)
Speaker: KHANDEKAR Ameya (Martinez), SCHOLZ Julia (Otsuka), BAUER Bernd (Martens)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Jay ShendureInstitute: University of WashingtonHost: Alex Stark
Monday Seminar (Internal)
Speaker: PASSERA Alessandro (Balzarotti), MILIVOJEV Nadja (Raible), HOLCIK Laurenz (Von Haeseler)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: IGOLKINA Anna (Nordborg), KRAMMER Teresa (Tanaka), AMANN Sascha Josef (Haselbach)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
European Worm Meeting 2022
We cordially invite you to the 2022 European Worm Meeting (EWM) taking place in Vienna, July 27-30. The meeting is hosted by the University of Vienna.
Monday Seminar (Internal)
Speaker: SCHMIDT Clara (Mendjan), GOGOVA Rebeca (Clausen), SAAD RODRIGUES Carolina (Schlögelhofer)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: YU Changwei (Brennecke), HAENDELER Simon (Von Haeseler), ALMEIDA Bernardo (Stark)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SEONG Jinwoo (Rivron), NAVA GARCIA Marintia Mayola (Dagdas), DENEKE Victoria (Pauli)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Xin ChenInstitute: Johns Hopkins UniversityHost: Fred Berger
Monday Seminar (Internal)
Speaker: KELLNER Max Josef (Penninger), LEITNER Marie-Christin (Mendjan), HORN Sabrina (Peters)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Mark DawsonInstitute: Peter MacCallum Cancer CentreHost: Johannes Zuber
Monday Seminar (Internal)
Speaker: OTSUKI Leo (Tanaka), LEV Itamar (Zimmer), HODAKOVA Zuzana (Haselbach)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Dominique BergmannInstitute: Stanford UniversityHost: Liam Dolan
Monday Seminar (Internal)
Speaker: BABADEI Olga (Decker), HOLZMANN Viktoria (Rivron), AYALA MUNOZ Farja (Plaschka)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Yves BarralInstitute: ETH ZurichHost: Shotaro Otsuka
Monday Seminar (Internal)
Speaker: TAKACS Zsuzsanna (Gerlich), DE LA CONCEPCION Juan Carlos (Dagdas), FEDL Anna (Busslinger)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Sophie PetropoulosInstitute: Karolinska InstitutetHost: Nicolas Rivron
Title to be announced
Speaker: Benoit BruneauInstitute: Gladstone InstitutesHost: Sasha Mendjan
Monday Seminar (Internal)
Speaker: GALLI Lucrezia (Tanaka), TERIYAPIROM Isaree (Koo), JACOBS Jelle (Stark)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Richard FlavellInstitute: Yale University School of MedicineHost: Meinrad Busslinger
Title to be announced
Speaker: Bernd BukauInstitute: ZMBHHost: Elif Karagäz
Monday Seminar (Internal)
Speaker: POPOVA Mariia (Peters), RITSCHKA Birgit (Tanaka), DOMBEY Rodolphe (Mari-Ordonez)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: INCARBONE Marco (Mittelsten Scheid), GRUNDMANN Lorenz (Haselbach), NEMCKO Filip (Stark)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: TELONI Federico (Gerlich), WALLNER Eva-Sophie (Dolan), PUSHPA BOSE Greeshma (Urban)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LIU Haijun (Nordborg), NAVALAYE Tsimafei (Ameres), NAAS Julia (Von Haeseler)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: CHUGUNOVA Anastasia (Pauli), RÖTZER Johannes (Dolan), JONSSON Gustav (Penninger)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: KLAUS Loni (Stark), BENEDUM Johannes (Slade), LITTLEBOY Jamie (Knoblich)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Daniel MucidaInstitute: Rockefeller UniversityHost: Meinrad Busslinger
Monday Seminar (Internal)
Speaker: ANTONIOLI Sumire (Leonard), LI Chong (Knoblich), PABST Gabriel (Zuber)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be announced
Speaker: Lacra BintuInstitute: Stanford UniversityHost: Alex Stark
Monday Seminar (Internal)
Speaker: DIEZMA Laura (Nordborg/Mari-Ordonez), GHOSH Dipannita (Grade), PATEL Rajvi (Matos)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Title to be annouced
Speaker: Adele MarstonInstitute: Wellcome Centre Cell Biology, University of EdinburghHost: Daniel Gerlich, Joao Matos
Monday Seminar (Internal)
Speaker: KORDIC Darja (Clausen), DEIBER Sebastian (Dolan), GEHRE Maja (Brennecke)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: ZMAJKOVIC Jakub (Zuber), MAURER Eric (Peters), NOGALES MORAL Adrian (Köhler)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: HUETTER Christiane (Menche), BASSAT Elad (Tanaka), PETRZILEK Jan (Ameres)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: KALIS Robert (Zuber), NAJM Ramsey (Knoblich), GEROCZ Emoke (Gerlich)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: AUGUSTO Pedro (Zimmer), POLISSENI Claudio (Tanaka), ELEWAUT Anais (Obenauf)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: GUO Pin (Dolan), DAO Pauline (Tessmar), JAVALI Alok(Rivron)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: STUART Hannah (Tanaka), KORESHOVA Alevtina (Burga), ZHAN Ni (Dagdas)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: CRONIN Shona (Obenauf), KANNO Tatsuo (Berger), PACHINGER Claudia (Dammermann)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SHUKLA Vikas (Berger), RODRIGUEZ TERRONES Diego (Tanaka), WIDEN Sonya (Burga)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: VOICHEK Yoav (Norborg), SESTINI Giovanni (Rivron), PETROULAKI Vasiliki (Matos)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: BRUNNER Hanna (Haselbach), FRIDRICH Arie (Berger), AKULOVA Vasilina (Swarts)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: DE SANTIS Martina (Rivron), BUENDIA Daniel (Mari-Ordonez), VISANPATTANASIN Supapat (Plaschka)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: VOJTEK Matus (Stark), LEHMANN Christian (Knoblich), LEE Du-Hwa (Belkhadir)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SPICER Maximilian (Gerlich), ESTIVILL I CAPAAROS Guillem (Obenauf), MURPHY Paul (Clausen)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: JÄGER Christina (Van der Veeken), PRADHAN Saurabh (Rivron), RAFANEL Baptiste (Brennecke)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: BELACIC Katarina (Haselbach), HARVEY Zachary (Berger), MILOJKOVIC Lidija (Urban)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: GOMEZ SEGALAS Alba (Balzarotti), KOLESNIKOVA Sofia (Gerlich), HANDLER Dominik (Brennecke)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: BAUCELLS Julia (Dammermann), PANAROTTO-PERICLES Melanie (Peters), VOICHEK Maya Shinan (Brennecke)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: DMITRIEV Vladimir (Goloborodko), HISANAGA Tetsuya (Berger), KHALDIEH Nina (Ameres)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SOMMER Theresa (Rivron), SHIRZADIAN YAZD Mehrta (Balzarotti), VERTESY Abel (Knoblich)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: POLIKARPOVA Anastasia (Tanaka), CHAKRABORTY Oisorjo (Grade), CORSI Flavia (Goloborodko)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: FESSELET Jeanne (Kovarik), KHAURATOVIC Uladzislava (Matos/Golobordko), SHEN Jingyi (Obenauf)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: PERNEBRINK Mattias (Tanaka), HOHMANN Ulrich (Brennecke/Plaschka), MANOLOVA Toni (Falk)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: WU Shuangyang (Dolan), SCARAMUZZA Federico (Tessmar), KROGULL Daniel (Burga)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: HEIDARI KHOEI Heidar (Rivron), BELL Caelan (Gerlich), GALUSKA Philipp (Djinovic)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: ABDRAKHMANOV Alibek (Dagdas), WILLIAMS Thomas (Clausen), GEISMANN Maximilian (Balzarotti)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: JELENIC Stela (Saha), PACHECO FIALLOS Franics Belen (Plaschka), FONTES OLIVEIRA Tiago Manuel (Penninger)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: NAGUMO WONG Sakurako (Knoblich), LORENZO ORTS Laura (Pauli), ROSS James (Burga)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: RAFFL Gerald (Ameres), SAJTOS Bettina (Zuber), ISHIHARA Keisuke (Tanaka)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: STEINACKER Thomas (Gerlich), EDER Stephanie (Zimmer), TIKANOVA Polina (Burga)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: SCHELLHAAS Ulla (Plaschka/Ameres), RUSCH Emma (Goloborodko), CLAVEL Marion (Dagdas)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: RADHAKRISHNA PILLAI Balashankar (Saha), ADELMANN Leonie (Raible), BLAHA Andreas (Pauli)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: VULIN Milica (Obenauf), MEREITER Stefan (Penninger), BINDL Michael (Leeb)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
Monday Seminar (Internal)
Speaker: LORBEER Franziska (Stark), MULVEY Hugh (Dolan), PÜHRINGER Florian (Burga)Institute: Open only to IMP/IMBA/GMI/Max Perutz Labs
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