New ways in diagnosing sepsis
During sepsis, quickly identifying the germs causing the infection is essential for patients as this condition is often lethal. Using knowledge gained at Arndt von Haeseler’s lab, MFPL Alumni Philip Stevens shows how to turn scientific expertise into a business career with social relevancy, making the diagnosis of sepsis quicker and easier.
Interfering with a greasy decoration is unhealthy for most picornaviruses
Picornaviruses are a group of pathogens that cause a variety of illnesses in humans. An interdisciplinary team of scientists of the Max F. Perutz Laboratories and other institutes, led by group leader Heinrich Kowalski, now report findings that could lead to new ways to cope with infections caused by these viruses.
Autophagy’s little helpers: How proteins mediate autophagosome-vacoule fusion
During autophagy the cell collects, degrades and recycles unwanted cellular material. This is an important process as cellular waste is ultimately harmful to the whole organism if it accumulates in the cells. Analogous to the processing of household waste, this mechanism requires certain protagonists and elements. Scientists from group leader Claudine Kraft’s Lab at Max F. Perutz Laboratories together with colleagues from the University of Freiburg have now gained new insight into the role of proteins in autophagosome-vacuole fusion.
Alwin Köhler promoted to Full Professor
Congratulations to Alwin Köhler, who recently became Professor of Mechanistic Cell Biology at the Medical University of Vienna.
Signaling in bacteria: How the cell envelope controls gene expression in bacteria
Bacteria need to be able to quickly adapt to changing environments – this is an absolute requirement for their survival. Adaptation often includes changes in the cell envelope, which protects the bacteria from their oftentimes hostile environment as it provides a barrier for harmful compounds including many antibiotics.
FWF standalone grant for Martin Leeb
MFPL group Leader Martin Leeb has been awarded a standalone grant by the FWF for his new project “Regulation of ES cell differentiation by NMD”. The grant will help the Leeb group’s effort to advance the understanding of the molecular underpinnings of early embryonic cell fate decisions via a process called differentiation.
Spotlight on the Dark Side of the Nucleus
The cell nucleus is a fascinating organelle, in which an organism’s DNA is protected, decoded and duplicated. The nucleus is surrounded by not one, but two membrane sheets: the outer and the inner nuclear membrane. These two membranes connect with each other at membrane openings occupied by nuclear pores. The outer nuclear membrane also connects to the endoplasmic reticulum (ER), an extended membrane network in the cytoplasm.
The Vienna Doctoral School (VDS) “Molecules of Life” retreat 2018
The third “Molecules of Life” retreat took place in Traunkirchen, Austria, continuing and strengthening the tradition of choosing locations next to Europe’s most beautiful lakes. The VDS’s mission of promoting research across many disciplines was reflected in the attendance of over 100 PhD students, postdocs and group leaders in disciplines ranging from Life Sciences, to Chemistry and Molecular Biology.
A system of check and balances in the blood
How Hematopoietic Stem Cells manage to switch between activation and dormancy
ERC Proof of Concept Grant for MFPL researcher Bojan Zagrovic
MFPL group leader Bojan Zagrovic (University of Vienna) is awarded a prestigious ERC Proof of Concept (PoC) Grant. The PoC, endowed with EUR 150.000, will support the work towards a potential commercial application based on findings from Bojan’s previously received ERC Starting Grant.
Tanja Kaufmann receives DOC Fellowship from the Austrian Academy of Sciences
We congratulate MFPL PhD student Tanja Kaufmann to securing a DOC Fellowship from the Austrian Academy of Sciences (OEAW). The fellowship will support Tanja’s research for the next three years.
Chromosomes in motion: what’s lamin got to do with it?
Meiosis is a specialized form of cell division, which occurs in all sexually reproducing organisms including animals, plants and fungi. During this process, different chromosomes exchange parts in an event called “crossing over”, leading to a new mix of maternal and paternal genomes. Additionally, the number of chromosomes is reduced by half. The resulting cells are called gametes, such as sperm or oocytes.