DNA “Zippers” – the role of proteins during cell division
Meiosis is an important cell division process found in sexually reproducing species. It requires a fine-tuned machinery that re-arranges and segregates chromosomes, a process supported by proteins. In a recent paper, Nicola Silva (a senior postdoc in Verena Jantsch’s Lab at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna) provides new insight in the inner workings of this machinery, especially the role of the BRCA1-BARD1 protein complex (BCD complex). The project was supported by the INDICAR program of the University of Vienna.
Cancer Research Run 2018
This year’s 12th cancer research run took place on October 6, 2018 at the "Altes AKH Campus" in Vienna. A warm, sunny fall day proved to be the perfect backdrop for 3000 runners including more than 100 company teams.
State Award for Emmanuelle Charpentier
Congratulations to former MFPL Group Leader Emmanuelle Charpentier to the Austrian Decoration for Science and Art! The prestigious honour was awarded on 3 October 2018 in Vienna by Austrian President Alexander van der Bellen.
Three uni:docs fellowships for MFPL PhD students
We congratulate our PhD students Martina Borroni, Maria Velkova, and Theresa Zekoll to their uni:docs, a fellowship designed for highly qualified doctoral candidates of the University of Vienna.
New ways in diagnosing sepsis
During sepsis, quickly identifying the germs causing the infection is essential for patients as this condition is often lethal. Using knowledge gained at Arndt von Haeseler’s lab, MFPL Alumni Philip Stevens shows how to turn scientific expertise into a business career with social relevancy, making the diagnosis of sepsis quicker and easier.
Interfering with a greasy decoration is unhealthy for most picornaviruses
Picornaviruses are a group of pathogens that cause a variety of illnesses in humans. An interdisciplinary team of scientists of the Max F. Perutz Laboratories and other institutes, led by group leader Heinrich Kowalski, now report findings that could lead to new ways to cope with infections caused by these viruses.
Autophagy’s little helpers: How proteins mediate autophagosome-vacoule fusion
During autophagy the cell collects, degrades and recycles unwanted cellular material. This is an important process as cellular waste is ultimately harmful to the whole organism if it accumulates in the cells. Analogous to the processing of household waste, this mechanism requires certain protagonists and elements. Scientists from group leader Claudine Kraft’s Lab at Max F. Perutz Laboratories together with colleagues from the University of Freiburg have now gained new insight into the role of proteins in autophagosome-vacuole fusion.
Alwin Köhler promoted to Full Professor
Congratulations to Alwin Köhler, who recently became Professor of Mechanistic Cell Biology at the Medical University of Vienna.
Signaling in bacteria: How the cell envelope controls gene expression in bacteria
Bacteria need to be able to quickly adapt to changing environments – this is an absolute requirement for their survival. Adaptation often includes changes in the cell envelope, which protects the bacteria from their oftentimes hostile environment as it provides a barrier for harmful compounds including many antibiotics.
FWF standalone grant for Martin Leeb
MFPL group Leader Martin Leeb has been awarded a standalone grant by the FWF for his new project “Regulation of ES cell differentiation by NMD”. The grant will help the Leeb group’s effort to advance the understanding of the molecular underpinnings of early embryonic cell fate decisions via a process called differentiation.
Spotlight on the Dark Side of the Nucleus
The cell nucleus is a fascinating organelle, in which an organism’s DNA is protected, decoded and duplicated. The nucleus is surrounded by not one, but two membrane sheets: the outer and the inner nuclear membrane. These two membranes connect with each other at membrane openings occupied by nuclear pores. The outer nuclear membrane also connects to the endoplasmic reticulum (ER), an extended membrane network in the cytoplasm.
The Vienna Doctoral School (VDS) “Molecules of Life” retreat 2018
The third “Molecules of Life” retreat took place in Traunkirchen, Austria, continuing and strengthening the tradition of choosing locations next to Europe’s most beautiful lakes. The VDS’s mission of promoting research across many disciplines was reflected in the attendance of over 100 PhD students, postdocs and group leaders in disciplines ranging from Life Sciences, to Chemistry and Molecular Biology.