The biomechanics of vascular ageing
Cardiovascular Diseases (CVD) lead to atherosclerosis and heart failure and are prevalent age-related illnesses in humans. In a new study, published in the renowned journal JCI, scientists from Roland Foisner’s group at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna, together with scientists from the Ludwig Boltzmann Cluster for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna and from the BOKU, Vienna describe the molecular mechanism behind CVD in the premature ageing disease Hutchinson-Gilford progeria syndrome (HGPS). The findings could also help understand normal ageing processes in the cardiovascular system.
University of Vienna and Medical University of Vienna extend successful collaboration with Max F. Perutz Laboratories
The University of Vienna and Medical University of Vienna are extending their successful collaboration with Max F. Perutz Laboratories. Rectors Heinz W. Engl from the University of Vienna and Markus Müller from MedUni Vienna signed an agreement to extend the Joint Venture until 2025.
ERC consolidator grant for Kristin Tessmar-Raible
Congratulations to MFPL group leader Kristin Tessmar-Raible, who has been awarded an “ERC Consolidator Grant” from the European Research Council. The grant will provide around two million Euros for a period of five years and is her second ERC grant.
Making sense of chromosomal chaos
When cells divide, chromosomes must be accurately segregated. Sometimes errors occur, leading to aneuploidy, a state where cells have an incorrect number of chromosomes. This chromosomal instability is in most cases harmful for cells, yet aneuploidy and high rates of errors in chromosome segregation are frequently observed in cancers, especially those that are resistant to treatment. How can cells adapt to and thrive in such a disadvantageous state?
Vienna RNA Meeting
The Vienna RNA Meeting 2018 took place 17-19 October at the Vienna Biocenter and was a big success - both in terms of the outstanding line-up of internationally renowned RNA expert as speakers, as well as the international echo of the meeting.
DNA “Zippers” – the role of proteins during cell division
Meiosis is an important cell division process found in sexually reproducing species. It requires a fine-tuned machinery that re-arranges and segregates chromosomes, a process supported by proteins. In a recent paper, Nicola Silva (a senior postdoc in Verena Jantsch’s Lab at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna) provides new insight in the inner workings of this machinery, especially the role of the BRCA1-BARD1 protein complex (BCD complex). The project was supported by the INDICAR program of the University of Vienna.
Cancer Research Run 2018
This year’s 12th cancer research run took place on October 6, 2018 at the "Altes AKH Campus" in Vienna. A warm, sunny fall day proved to be the perfect backdrop for 3000 runners including more than 100 company teams.
State Award for Emmanuelle Charpentier
Congratulations to former MFPL Group Leader Emmanuelle Charpentier to the Austrian Decoration for Science and Art! The prestigious honour was awarded on 3 October 2018 in Vienna by Austrian President Alexander van der Bellen.
Three uni:docs fellowships for MFPL PhD students
We congratulate our PhD students Martina Borroni, Maria Velkova, and Theresa Zekoll to their uni:docs, a fellowship designed for highly qualified doctoral candidates of the University of Vienna.
New ways in diagnosing sepsis
During sepsis, quickly identifying the germs causing the infection is essential for patients as this condition is often lethal. Using knowledge gained at Arndt von Haeseler’s lab, MFPL Alumni Philip Stevens shows how to turn scientific expertise into a business career with social relevancy, making the diagnosis of sepsis quicker and easier.
Interfering with a greasy decoration is unhealthy for most picornaviruses
Picornaviruses are a group of pathogens that cause a variety of illnesses in humans. An interdisciplinary team of scientists of the Max F. Perutz Laboratories and other institutes, led by group leader Heinrich Kowalski, now report findings that could lead to new ways to cope with infections caused by these viruses.
Autophagy’s little helpers: How proteins mediate autophagosome-vacoule fusion
During autophagy the cell collects, degrades and recycles unwanted cellular material. This is an important process as cellular waste is ultimately harmful to the whole organism if it accumulates in the cells. Analogous to the processing of household waste, this mechanism requires certain protagonists and elements. Scientists from group leader Claudine Kraft’s Lab at Max F. Perutz Laboratories together with colleagues from the University of Freiburg have now gained new insight into the role of proteins in autophagosome-vacuole fusion.