Chromosomes in motion: what’s lamin got to do with it?
Meiosis is a specialized form of cell division, which occurs in all sexually reproducing organisms including animals, plants and fungi. During this process, different chromosomes exchange parts in an event called “crossing over”, leading to a new mix of maternal and paternal genomes. Additionally, the number of chromosomes is reduced by half. The resulting cells are called gametes, such as sperm or oocytes.
228.000 visitors at the Long Night of Research 2018
On April 13th, the latest edition of Austria’s largest science outreach event “Long Night of Research” took place all over the country. More than 220.000 visitors of all ages seized the opportunity to visit 265 different locations, learn more about the exciting and diverse world of research in Austria – and also broke the visitor record set two years ago.
MFPL involved in the new interdisciplinary Comammox research platform
MFPL scientist and head of the Department of Structural and Computational Biology Kristina Djinovic-Carugo, together with Michael Wagner (Head of the Research Network Chemistry Meets Microbiology and the Department of Microbiology and Ecosystem Science), Holger Daims (group leader at the Department of Microbiology and Ecosystem Science), and Andreas Richter (Head of the Terrestrial Ecosystems Unit at the Department of Microbiology and Ecosystem Science) received funding of €470.000 from the University of Vienna for their new interdisciplinary research platform focussing on comammox bacteria.
ERC Starting Grant for physicist Thomas Juffmann
Thomas Juffmann is awarded a renowned ERC Starting Grant of the European Research Council, which funds ground-breaking basic research. The funding of €1.5 million enables Juffmann to develop new microscopy methods at the interface of physics and biology. Dr. Juffmann, a member of the University Physics department, will now establish his research group at MFPL to foster interdisciplinarity and innovative collaborations.
Four FWF grants for MFPL scientists
We congratulate our researchers Andreas Bachmair, Thomas Decker, Verena Jantsch and Dea Slade on being awarded four FWF grants for their proposed research projects. The FWF will support their future work with a total of more than €1.5 million over the next three years.
Doc.Award 2018 for Iva Lučić
Congratulations to Iva Lučić on her Doc.Award from the University of Vienna! Iva recently completed her PhD in Thomas Leonard’s lab at the MFPL.
Female power at NaturTalente 2018: Now with focus on Life Sciences
The competence program of UNIPORT, “NaturTalente”, has entered its fourth round in 2018. Designed specifically for excellent students, the initiative aims at establishing a network between students from life sciences, chemistry, and the Medical University of Vienna and influential industry partners.
International FWF grant for MFPL scientist Martin Leeb
We congratulate stem cell researcher Martin Leeb on winning an International FWF grant for the research project “Systems biology of embryonic stem cell differentiation”.
A technology award for the University of Vienna and MFPL
Dr. Nadezda Sedlyarova, researcher of the University of Vienna at the Max F. Perutz Laboratories (MFPL), and Dr. Jürgen Mairhofer of enGenes Biotech GmbH, were awarded one of three prizes from START:IP 2018 for their collaborative evaluation of an innovative technology developed in the laboratory of Prof. Renée Schroeder at the MFPL.
Learning about a human genetic disease from plants
Fanconi anemia is a rare human genetic disease characterized by severe pathologies like predisposition to cancer, congenital defects and infertility. Previous studies have shown that most of the genes affected in the disorder are implicated in DNA repair. As studies on germ cells (the precursor cells of egg and sperm cells) carrying mutations in Fanconi anemia genes have proven to be extremely challenging in animal models, the Schlögelhofer group at MFPL have used the model plant Arabidopsis thaliana to investigate the role of a key protein in Fanconi anemia – Fanconi anemia D2 protein (FANCD2).
Molecule linked to antagonistic mechanisms that keep muscle proteins in shape
Scientists in Vienna discover two distinct roles for the molecule UNC-45 in keeping muscle proteins in the right shape: on its own it steers the assembly of a muscle protein; in conjunction with a partner it triggers the degradation of severely damaged muscle proteins. The findings, reported in Nature Communications, may help to better understand muscular diseases.
Collecting the right waste: insights into the molecular mechanism of p62-mediated autophagy
Waste management is a big problem, and not only for us but also for our cells. In order to remain healthy, our cells must constantly collect and degrade the waste that is produced inside them. If this harmful material accumulates cells will ultimately die, affecting the health of the entire organism. For example, many degenerative diseases such as Alzheimer’s and Parkinson’s diseases are thought to arise from the accumulation of harmful waste inside the cells.